Researchers publish insights into transporter EmrE, utilize new method of imaging

Biochemistry Professor Katie Henzler-Wildman and her team of researchers have published findings on the structure and dynamics of EmrE, utilizing a new method to determine the protein’s structure in greater detail than had been previously available. EmrE is a membrane protein that may provide key insight into antibiotic resistance, a rising public health concern. EmrE …

Rienstra joins department, NMRFAM

Chad Rienstra’s scientific career was jumpstarted by four years of undergraduate research, where he developed a broad interest in biology, chemistry, physics, mathematics, and engineering. It’s this commitment to interdisciplinary research and education that he brings to bear years later as he joins the University of Wisconsin–Madison Department of Biochemistry as a professor. After his …

Woonghee Lee of Markley Lab earns grant to improve NMR computation

Woonghee Lee in the lab of biochemistry professor John Markley plans to improve data analysis for the burgeoning technique of solid-state nuclear magnetic resonance (NMR) spectroscopy thanks to a grant from the National Science Foundation. Lee’s work will entail a long list of software development. He and his group will develop, test, perfect, and release a full automation and visualization system.

Chasing the tail: Biochemists zone in on bacterial transporter’s tip as its secret to antibiotic resistance

Professor Henzler-Wildman and her team have found that proton and drug movements are not as strictly coupled as they thought in EmrE. This transporter can actually also move drugs and protons across the membrane in the same direction, as well as the opposite direction — introducing the option of moving molecules both into or out of the cell.