Decoding properties hidden within a protein’s 3D structure can be tricky. Scientists in the Sussman Lab identified a molecule that could unlock secrets held within proteins’ folds.
Research
Research in Brief: The What, Why, and How
Diversity is the key to survival for beneficial bacteria living in your gut. Now, scientists have new tools to explore this diversity.
Study Reveals Peculiar Movements of Cholesterol in Cellular Membranes
Much remains unknown about cholesterol. New research reveals how these lipid molecules move in cell membranes, which could have broad implications for future studies.
Cryo-EM Studies Reveal the ‘High-wire Act’ of Bacterial Replication
Researchers used Cryo-EM to precisely detail how bacterial proteins act like emergency first responders, repairing broken DNA on the fly.
When Antibiotics Deplete Our Gut Microbiome, a Human Gut Pathogen Takes Advantage
A deleterious bacterial infection can take hold when the diverse community of bacteria in the gut microbiome are killed with antibiotics.
Simcox Named HHMI Freeman Hrabowski Scholar
With funding from a new HHMI program, biochemistry professor Judith Simcox works toward more inclusive lines of scientific inquiry.
Hoskins, Hull Labs Receive Badger Challenge Award
The Hoskins and Hull Labs will be joining forces in the fight against life-threatening fungal infections common among leukemia and lymphoma patients thanks to funding from the Badger Challenge Award.
From ‘blobology’ to atomic precision: Wisconsin’s leadership on cryo-EM imaging
Cryo-electron microscopy drives a promising collaboration between the UW-Madison Department of Biochemistry and the Morgridge Institute.
Metabolism research at Wisconsin Tech Council meeting
At a meeting of the Wisconsin Tech Council (WTC), biochemistry assistant professor and Morgridge Institute for Research investigator Jason Cantor described the renaissance taking place in metabolism research.
Folds in pUG molecules turn off genes and could provide clues about human disease
Biochemistry researchers have found that, like the curlicue tails of the dogs their nickname alludes to, pUG sequences can fold tightly around themselves. This “pUG fold” is important for their ability to silence genes.