With support from the National Institutes of Health 2022 High Risk, High Reward New Innovator Awards, assistant professors Ci Ji Lim and Amy Weeks are pursuing some of their most unconventional ideas about repeating DNA sequences and the way cells reorganize proteins as they receive signals from outside their walls.
telomeres
Enzymes, proteins work together to tidy up tail ends of DNA in dividing cells
Biochemistry researchers have described the way an enzyme and proteins interact to maintain the protective caps, called telomeres, at the end of chromosomes, a new insight into how a human cell preserves the integrity of its DNA through repeated cell division.