Bill Reznikoff’s Tn5 Legacy

Photo of Bill Reznikoff

“It’s quite a story,” says Caruccio. “UW-Madison had a researcher who spent his career trying to understand this strange and unexpected phenomenon — DNA jumping from place to place inside a single cell. Eventually, Bill Reznikoff discovered the enzyme responsible for that, which would have been a landmark by itself. But then this small biotech company in Madison picked up on the enzyme, made an improvement, used it to speed up next-generation sequencing, and was sold to the maker of the fastest gene sequencers on the market.”

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