The Metabolism of Lipids: Implications in Human Diseases

34th Steenbock Symposium - May 22, 2011 to May 25, 2011
University of Wisconsin - Madison


Sunday, May 22, 2011

6:30pm - 8:00pm -  Reception and Registration 
Pick up conference materials in the Wisconsin Institutes for Discovery Atrium - 330 North Orchard Street

All the Symposium talks will be held in The Forum at the
Wisconsin Institutes for Discovery
330 North Orchard Street

Monday, May 23, 2011

7:30am - Continental Breakfast

8:00am - Welcoming Remarks
James M. Ntambi - University of Wisconsin - Madison

8:10am - Opening Remarks
Hector DeLuca - Harry Steenbock Research Professor - University of Wisconsin - Madison

8:25am - Regulation of Lipid Metabolism
(Chair: Rosalind Coleman)

8:30am - Lipid Metabolism: Location, Location, Location
Rosalind Coleman - University of North Carolina

9:00am - Metabolic Control by Lipid Droplet Proteins
Michael P. Czech - University of Massachusetts

9:30am - Perilipin Control of Lypolysis
​Dawn Brasaemle - Rutgers

10:00am-10:20am - Morning Coffee Break

10:20am - How Cells Fatten Up: Fat Synthesis and Lipid Droplets
Robert Farese - University of CA, San Francisco

10:50am - Regulation and Function of Adipose Lipolysis
Hei Sook Sul - Berkeley

11:20am - Deciphering the Roles of Lipin Family Members in Tissue Lipid Homeostasis
Karen Reue - UCLA

11:50am - Intestinal Triacylglycerol Metabolism and Energy Balance
Eric Yen - University of Wisconsin - Madison

12:20pm - 1:10pm - Lunch

12:30pm - 7:30pm - Poster on Display and Discussion - WID Atrium

1:15pm - Signaling in Adipocytes and Regulation of Body Weight
(Chair: Xiaoli Chen)

1:20pm - Role of Wnt Signaling in Adipocyte Differentiation and Metabolism
Ormond A. MacDougald - University of Michigan Medical School

1:50pm - Transcriptional Networks of Fat Cell Development
Susanne Mandrup - University of Southern Denmark

2:20pm - Adipose ChREBP, Lipogenesis, and Insulin Sensitivity
Barbara Kahn - Harvard

2:50pm - 3:10pm - First Afternoon Break

3:15pm - Lipocalin 2 as an Important Regulator of Energy Metabolism
Xiaoli Chen - University of Minnesota

3:45pm - Lipoprotein Lipase in the Brain Regulates Energy Balance and Body Weight
Robert Eckel - University of Colorado, Denver

4:15pm - How Glucose and Fructose Alter Hypothalamic Signaling and Feeding Behavior
M. Daniel Lane - Johns Hopkins School of Medicine

4:45pm - 5:05pm - Second Afternoon Break

5:10pm - Metabolism in Heart and Muscle
(Chair: Agnieszka Dobrzyn)

5:15pm - Systems Genetics Approaches to Complex Cardiovascular Traits
Aldons J. Lusis - UCLA

5:45pm - Correcting Cardiac Lipotoxicity
​Ira Goldberg - Columbia University

6:15pm - Unsaturated Fatty Acids and Regulation of Cardiac Energy Metabolism
Agnieszka Dobrzyn - Nencki Institute of Experimental Biology, Warsaw, Poland

6:45pm - Mitochondrial Stress and Metabolic Dysfunction in Skeletal Muscle
Deborah Muoio - Duke University

Tuesday, May 24th, 2011

8:00am - Continental Breakfast

8:25am - Liver and Skin Metabolism
(Chair: Sudha Biddinger)

8:30am - The Control of Lipid Metabolism in Insulin Resistant States
Sudha Biddinger - Children’s Hospital of Boston

9:00am - Molecular Mediators of Hepatic Steatosis
​Jay Horton - University of Texas Southwestern Medical Center

9:30am - Multiple Effects of Xbp1s on Hepatic Lipid Metabolism
Philipp Scherer - University of Texas Southwestern Medical Center

10:00am - A Nutrient Sensor Mechanism for Control of Lipid Oxidation
Pere Puigserver - Harvard

10:30am - 11:00am - Morning Coffee Break

11:00am - Metabolic Regulation by Immune Signaling
Chih-Hao Lee - Harvard

11:30am - Lipids in Skin Physiology, Health and Disease
Apostolos Pappas - Johnson & Johnson Skillman, NJ

12:00pm - A Role for Skin Stearoyl-CoA Desaturase-1 in Obesity and Diabetes
James M. Ntambi - University of Wisconsin - Madison

12:30pm - Investigating the Roles of Lipids in Disease and Chemical Toxicities using Metabolomics
​Frank Gonzalez - National Cancer Institute, Bethesda

1:00pm - 1:50pm - Lunch

1:55pm - Diabetes
(Chair: Alan Attie)

2:00pm - Gene Loci for Type 2 Diabetes in Mice
Alan Attie - University of Wisconsin - Madison

2:30pm - Metabolomics Used for Understanding Chronic Disease Mechanisms
Christopher Newgard - Duke University

3:00pm - α3(V) Collagen Ablation in Mice Induces Diabetes-related Symptoms via Effects on Pancreatic Islets and Peripheral Tissues
Daniel Greenspan - University of Wisconsin - Madison

3:30pm - 3:45pm - Afternoon Break

3:45pm - Lipid-sensing Transcription Factors and Beta-cell Biology
Joyce Repa - University of Texas Southwestern Medical Center

4:15pm - Inflammation and Macrophage Leukotriene Synthesis
David Bernlohr - University of Minnesota

4:45pm - Phospholipid Methylation, Diabetes and Obesity
Dennis Vance - University of Alberta

5:15pm - Blood Lipids and Body Fat – Making the Connection
Ronald Krauss - Children’s Hospital Oakland Research Institute

6:00pm - Social Time - Wisconsin Institutes for Discovery Atrium

7:00pm - Evening Banquet - Wisconsin Institutes for Discovery Atrium

Wednesday, May 25, 2011

8:00am - Continental Breakfast

8:25am - Cholesterol Metabolism; Stem Cells; Atherosclerosis
(Chair: Richard Deckelbaum)

8:30am - Bile Acid Signaling in Regulation of Atherosclerosis and Vascular Calcification
Makoto Miyazaki - University of Colorado, Denver

9:00am - Insulin, Diabetes and the Control of Brain Cholesterol Metabolism
Ronald Kahn - Harvard

9:30am - Control of Cholesterol Homeostasis by LXRs
​Peter Tontonoz - UCLA

10:00am - Sterol/Oxysterol Regulation of Macrophage Gene Expression
Christopher Glass - University of CA, San Diego

10:30am - ABC Transporters and ApoE in the Regulation of Hematopoietic Stem Cell Proliferation, Monocytosis and Atherogenesis
​Alan Tall - Columbia University

11:00am - Omega-3 Fatty Acids: Preventive and Therapeutic Molecules for Liver, Heart, and Brain
Richard Deckelbaum - Columbia University

11:30am - Closing Remarks
James M. Ntambi - University of Wisconsin - Madison