Gene Expression, Transposition, Genomic and Other Life Sciences

30th Steenbock Symposium - May 20, 2004

The Department of Biochemistry at the University of Wisconsin has been an incredible breeding place for two different routes of scientific inquiry. The first path is exemplified by an extremely focused study of one particular problem probing ever deeper into its intricacies. The second model leads to diversification in which one line of study, while continuing to dig deeply, is primarily manifested by the addition of new areas of inquiry usually through the export of shared techniques but also through the recognition of underlying commonalities.

This Steenbock Symposium will exemplify deep scientific diversification. The Reznikoff lab initiated its work studying the molecular biology of bacterial gene regulation. It diversified into genomics and to studying the transposon structures that carried genes whose expression was being analyzed. This led to the analysis of transposition that in turn linked to mechanistically similar phenomena such as retroviral integration. In addition, those who had been trained in the laboratory moved into incredibly diverse fields such as RNA metabolism, gene silencing, DNA replication, membrane embedded functions and technology development. All of these and more will be highlighted at the 30th Steenbock Symposium.

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