The Biochemistry Optical Core provides state-of-the-art instrumentation for light and fluorescence based microscopy, including epifluorescence, confocal, and super-resolution imaging. Established by a faculty-approved investment from the Department of Biochemisty Endowment, our goal is to serve the campus research community by providing access to and training on basic and advanced light microscopy techniques.  

Imaging techniques available through the core now include:

  • Standard fluorescence
  • Super- Resolution Microscopy
            -STORM/PALM
            -SIM
  • Live-cell long term imaging
  • Point Scanning Confocal
  • Deconvolution
  • 3D particle tracking
  • Fluorescence spectral detection
  • TIRF
  • FRET
  • FRAP/FLIP
  • Photoactivation/uncaging
  • Calcium imaging
  • Single molecule imaging

Available Equipment Include

Nikon A1R-Si+ Confocal Microscope

Nikon SIM (Structured Illumination Microscope)

Nikon STORM/TIRF/epifluorescence Microscope

Offline Nikon Elements Analysis Stations