BIOCHEMISTRY

Brian H. Carrick

Contact

University of Wisconsin-Madison
433 Babcock Dr.
Madison, WI 53706

bcarrick@wisc.edu

Education

2015-Present - Ph.D. Candidate, Biochemistry, University of Wisconsin-Madison, Madison, WI.
2011-2015 - B.S. with Honors, Biochemistry, University of Michigan, Ann Arbor, MI.

Research Experience

Graduate

2015-Present - UW-Madison, Department of Biochemistry

Advisors:
Judith Kimble, HHMI Investigator and Vilas Professor of Biochemistry
Marvin Wickens, Max Perutz Professor of Molecular Biology and Biochemistry

Focus:
RNA regulatory networks in the C. elegans germline.

Undergraduate

2011-2015 - University of Michigan, Department of Biological Chemistry

Advisor:
David Engelke, Professor of Biological Chemistry

Thesis:
“A Novel Recombinant DNA System for High Affinity Purification of Proteins in Saccharomyces cerevisiae.”

Focus:
Mechanisms of gene silencing near tRNA genes

Publications

Douglas F. Porter*, Aman Prasad*, Brian H. Carrick, Peggy Kroll-Conner, Marvin Wickens, & Judith Kimble. Toward Identifying Subnetworks from FBF Binding Landscapes in Caenorhabditis Spermatogenic or Oogenic Germlines. G3 (Bethesda). 2019 Jan 9.

Brian H. Carrick, Linxuan Hao, Philip J. Smaldino, and David R. Engelke. A Novel Recombinant DNA System for High Affinity Purification of Proteins in Saccharomyces cerevisiae.  G3 (Bethesda). 2015 Dec 29.

Paul D. Good, Ann Kendall, James Ignatz-Hoover, Erin L. Miller, Dave A. Pai, Sara R. Rivera, Brian Carrick, and David R. Engelke. Silencing near tRNA genes is nucleosome-mediated and distinct from boundary element function. Gene 526(1):7-15, 2013.

Fellowships, Awards, Honors

2020-Present - William H. Peterson Fellowship in Biochemistry
2020 - RNA Society Travel Award
2019 - 3rd Place Poster Prize: FASEB RNA Localization and Local Translation Conference
2019 - Wisconsin Alumni Research Foundation Travel Award
2019 - Society for Developmental Biology Early Career Trainee Award
2017 - Honorable Mention Presentation Award, 21st International C. elegans Meeting
2017 - Villas Travel Grant
2017 - Steenbock Research Award
2017-Present - NSF Graduate Research Fellow
2015 - Graduated with Honors in Biochemistry, University of Michigan
2013 - Biomedical and Life Sciences Fellowship, University of Michigan

Teaching, Mentoring

Graduate: University of Wisconsin-Madison

2015-Present - Undergraduate and Post-Baccalaureate Student Mentor

• I have mentored a post-baccalaureate student and two undergraduate students. As a mentor, I strive to guide these students towards critical and independent thinking, which allows them to approach and assess a research question. This is done through hands-on intensive instruction in many techniques ranging from PCR to manipulation of C. elegans that gradually leads to independent work that I directly supervise.

Fall 2016, Spring 2017 - Biochemistry 550 (Biochemical Methods), Teaching Assistant

• Lead laboratory section (4 hours) every week to instruct students as they perform experiments. I directed lectures beforehand to educate the students on the experimental theory and practice for techniques used in the laboratory section.

Fall 2018 - Biochemistry of Development, Instructor

• Conceived and instructed a literature-based discussion class for senior undergraduate students that focused on biochemical methods to study questions in developmental biology. Topics included patterning, germline stem cells, and neuronal development.

Selected Conference and Poster Presentations

2019 - FASEB RNA Localization and Local Translation Meeting. Snowmass Village, CO.
Carrick BH, et al. Unraveling combinatorial control of an RNA regulatory network in stem cells.
3rd Place Poster Presentation Prize.

2019 - Department of Biochemistry Poster Session. Madison, WI.
Carrick BH, et al. Unraveling combinatorial control of an RNA regulatory network in stem cells.

2018 - Integrated Program in Biochemistry Department Retreat. Madison, WI.
Carrick BH, et al. Unraveling combinatorial control of an RNA regulatory network in stem cells.

2017 - 21st International C. elegans Meeting. Los Angeles, CA.
Carrick BH, et al. Genomic analyses of interactions that govern an RNA regulatory network in stem cells.
Honorable Mention Prize Winner.

2014 - American Chemical Society Undergraduate Research Conference.  Ann Arbor, MI.
Carrick BH and Engelke DR. A Novel Recombinant DNA System for Tandem Affinity Purification of Proteins.

2014 - M Cubed Symposium.  Ann Arbor, MI.
Angevine KR, Carrick BH, Engelke DR. Sensitive Detection of Molecular Markers for Disease and Experimental Tools.

2014 - International Conference on Transcription by RNA Polymerases I, III, IV, and V: Odd Pols 2014. Ann Arbor, MI.
Carrick BH and Engelke DR. A New Recombinant DNA System for Tandem Affinity Purification of Proteins.

2012 - Michigan Research Community Symposium.  Ann Arbor, MI.
Carrick BH, Good PD, and Engelke DR. Chromatin-Medicated Silencing Near tRNA Genes.