Lab Members

Photo of Tom Record

Prof. Tom Record (Principal Investigator)

Steenbock Professor in Chemical Sciences; John D. Ferry Professor of Chemistry & Biochemistry. B.A., Yale University; Ph.D.: University of California-San Diego
Faculty page
Research Description:
Protein-nucleic acid interactions, including kinetics and mechanism of transcription initiation, characterization of DNA wrapping in protein DNA complexes, development of small molecule solutes as thermodynamic and mechanistic probes of protein and DNA conformational changes.

 

Dr. Irina Shkel (Assistant Scientist)

Department: Biochemistry, Chemistry

Research Description:

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Dr. Kate Henderson (Postdoc)

Department: Biochemistry
Subgroup: RNA polymerase
Previous Education:BS (Chemistry), PhD (Chemistry)
Research Description:
Pastime Activities/Hobbies: Running, biking, reading, playing board games

Photo of Rituparna Sengurpta

Rituparna Sengupta (Postdoc)

Program: Biophysics
Subgroup: Solutes
Previous Education: B.Tech (Biotechnology)
Research Description:
Using solutes as probes of large conformational changes in steps and transitions states of biopolymer processes.
Pastime Activities/Hobbies: Painting, Reading and Writing

Photo of Xian Cheng

Xian Cheng (Graduate, 4th year)

Program: Biophysics
Subgroup: Solutes
Previous Education: BS(Chemistry)
Research Description:
Studying interactions of amide compounds with protein and Nucleic acid functional groups and using these solutes as probes to detect biopolymer process.
Pastime Activities/Hobbies: Music, Movie

Photo of Munish Chhabra

Munish Chhabra (Graduate, 2nd year)

Program: Biophysics
Subgroup:RNA polymerase
Previous Education: B.Tech (Biotechnology)
Research Description:
Understanding the process of transcription initiation using fluorescence measurements (at both bulk and single molecule level).
Pastime Activities/Hobbies: Swimming and Running

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Kevin Lauterjung (Graduate, 1st year)

Program: Biophysics
Subgroup: RNA polymerase
Previous Education: B.A.S. (Sound Arts)
Research Description:

Pastime Activities/Hobbies:All things music, Irish dance, mushroom foraging, backpacking, brewing, puns

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Emily Zytkiewicz (Manager/Associate Research Specialist)

Subgroup: Solutes
Previous Education: B.S. (Biochemistry)
Research Description:
Quantifying chemical interactions of polyols with protein functional groups in order to develop solute probes of biopolymer processes
Pastime Activities/Hobbies: dancing, hiking, camping, gardening

Photo of Sherry Cheng

Lixue Cheng (Sherry) (Research Intern)

Personal Page | Group page maintenance

Major(s): BS in Chemistry, Math, Biochemistry, Molecular Biology and Computer Science (minor)
Subgroup: Solutes
Research Description:
Understanding the preferential interactions between different (solutes polyols, PEG and Hofmeister salts) and aromatic compounds (nucleobases, base analogs and PAH).
Past Time Activities/Hobbies: Music

photo of Yan Ma

Yan Ma (Research Intern)

Previous Education: B.S. Chemical Engineering
Subgroup: Solutes
Research Description:
Measuring and analyzing the interactions of amide compounds with protein functional groups using vapor pressure osmometry.
Past Time Activities/Hobbies: Sports, music, and traveling

 

Cristen Molzahn (Research Intern)

Major(s):
Subgroup:
Research Description:
Pastime Activities/Hobbies:

Photo of Lindsey Felth

Lindsey Felth (Research Intern)

Major(s): BA in Biochemistry and German (minor)
Subgroup: RNA Polymerase
Research Description:
Studing the kinetics of open complex formation and dissociation, the ratios of abortive/productive product ratios in trascription initiation and the effect of changing the discriminator region
Pastime Activities/Hobbies: exploring nature, reading and music

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Andrew Mcclyman (Undergraduate)

Major(s):  Biochemistry
Subgroup:  Solutes
Research Description:
Pastime Activities/Hobbies:

Sumin Yang (Undergraduate)

Major(s):  Biochemistry
Subgroup:  Solutes
Research Description:  Measuring the interactions of polyols with functional groups of proteins using Vapor Pressure Osmometry.
Pastime Activities/Hobbies:  playing tennis, watching The Daily Show

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Can Xu (Undergraduate)

Major(s): Chemical Engineering
Subgroup: Solutes
Research Description:
Pastime Activities/Hobbies: Table tennis (UW-Madison Table Tennis Women's Team Member)

photo of Claire Evensen

Claire Evensen (Undergraduate)

Major(s): Biochemistry and Mathematics
Subgroup: RNA polymerase
Research Description:  Studying free energy in scrunching and characterizing pause points in RNA polymerase transcription 
Pastime Activities/Hobbies: Music, hiking, baking, reading

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Christina McNerney (Undergraduate)

Major(s): Biochemistry
Subgroup: RNA Polymerase
Research Description:
Pastime Activities/Hobbies: Playing clarinet, reading

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Clare Kai Cimperman (Undergraduate)

Major(s): Senior, Biochemistry, Chinese
Subgroup: RNA polymerase
Research Description:
Using fluorescence effects to study conformational changes in DNA and RNAP during transcription initiation.
Pastime Activities/Hobbies: Ice skating, dancing, going to concerts, traveling

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David Lambert (Undergraduate)

Major(s): Biochemistry
Subgroup: Solutes
Research Description:
Pastime Activities/Hobbies:

photo of Ellen Restyanszki

Ellen Restyanszki (Undergraduate)

Major(s): Junior, Biomedical Engineering
Subgroup: RNA Polymerase
Research Description:
Studying the kinetics of open complex formation of RNAP with different DNA promoter sequences.
Pastime Activities/Hobbies: Volleyball, traveling, watching football

photo of Emilio

Emilio Jacobo (Undergraduate)

Major(s): Sophomore Biology
Subgroup: Solutes
Research Description:
Predicting and Interpreting the Hofmeister Effects of Different Salts and sugars with Nucleic Bases and Aromatic Compounds.
Pastime Activities/Hobbies:Video Games, Watching Old movies, Playing Guitar, Rock Climbing

Photo of Guanyu Liao

Guanyu Liao (Undergraduate)

Major(s): Biochemistry, Statistics
Subgroup: RNA Polymerase
Research Description:
The association and dissociation kinetics of RNA polymerase and the role of the discriminator region on the kinetics.
Pastime Activities/Hobbies: Volleyball, traveling, watching football

 

Photo of Jack Kalloch

Jack Kalloch (Undergraduate)

Major(s): Junior, Microbiology
Subgroup: Solutes
Research Description:
Using solutes as probes of large conformational changes in steps and transitions states of biopolymer processes.
Pastime Activities/Hobbies: Disc Golf, Longboarding, Snowboarding, Camping

Photo of Joseph Kraft

Joseph Kraft (Undergraduate)

Major(s): Biochemistry and Chemistry
Subgroup: RNA Polymerase
Research Description:
Studying mutations in RNAP to gain insight into how specific domains participate in open complex formation and transcription.
Pastime Activities/Hobbies: Any and all sports, guitar, camping

Photo of Taylor Bye

Taylor Bye (Undergraduate)

Major(s): Psychology and Criminal Justice
Subgroup: solutes
Research Description:  Measuring the interactions of polyols with functional groups of proteins using Vapor Pressure Osmometry.
Pastime Activities/Hobbies:  Basketball, soccer, pool, watching TV shows and movies, listening to music, traveling

Photo of Sarah Dyke

Sarah Dyke (Undergraduate)

Major(s): Biochemistry and French
Subgroup: RNA Polymerase
Research Description: 
Pastime Activities/Hobbies: 

 

 

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LuLu Callies (Undergraduate)

Major(s): Biology
Subgroup: RNA Polymerase
Research Description:
Pastime Activities/Hobbies: Music, reading

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Nicholas Visser (Undergraduate)

Major(s): Junior, Math and Chemistry
Subgroup: RNA Polymerase
Research Description:
Pastime Activities/Hobbies: running, basketball, and making music

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Rebecca Brodziski (Undergraduate)

Major(s): Junior, Biomedical Engineering
Subgroup: RNA Polymerase
Research Description:
Studying the kinetics of open complex formation of RNAP and different DNA promoter sequences.
Pastime Activities/Hobbies: Music

Photo of Runyu Hong

Runyu Hong (Undergraduate)

Major(s): Senior, Biochemistry
Subgroup: Solutes
Research Description:Predicting and Interpreting the Hofmeister Effects of Different Salts with Nucleic Bases and Aromatic Compounds Using Solubility Assay.

Pastime Activities/Hobbies: Playing the piano and cycling

Photo of Sami Powell

Sami Powell (Undergraduate)

Major(s): Sophomore, Biochemistry, Microbiology, and French
Subgroup: RNA Polymerase
Research Description:
Studying the forward kinetics of teh RNAP open complex with the fast mixer.
Pastime Activities/Hobbies: Volleyball, tennis, and reading

 

Yao Yao (Undergraduate)

Major(s):
Subgroup: Solutes
Research Description:
Pastime Activities/Hobbies: