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Publications


The publications on this site are being made available to the academic community for
use in teaching and research. All copyrights remain intact.

Peer-Reviewed Journal Articles (Original Research)

  1. Mechanism-based enzyme inactivation using an allyl sulfoxide–allyl sulfenate ester rearrangement. Michael Johnston, Ronald Raines, Christopher Walsh, and Raymond A. Firestone (1980). Journal of the American Chemical Society 102, 4241–4250. [PDF]
  2. Mechanistic studies on reactions of bacterial methionine γ-lyase with olefinic amino acids. Michael Johnston, Ronald Raines, Michael Chang, Nobuyoshi Esaki, Kenji Soda, and Christopher Walsh (1981). Biochemistry 20, 4325–4333. [PubMed] [PDF]
  3. Mechanistic studies on the pyridoxal phosphate enzyme 1-aminocyclopropane-1-carboxylate deaminase from Pseudomonas sp. Christopher Walsh, Robert A. Pascal, Jr., Michael Johnston, Ronald Raines, Dinesh Dikshit, Allen Krantz, and Mamoru Honma (1981). Biochemistry 20, 7509–7519. [PubMed] [PDF]
  4. The active site of triosephosphate isomerase: In vitro mutagenesis and characterization of an altered enzyme. Donald Straus, Ronald Raines, Eric Kawashima, Jeremy R. Knowles, and Walter Gilbert (1985). Proceedings of the National Academy of Sciences, U.S.A. 82, 2272–2276. [PubMed] [PDF]
  5. Reaction energetics of a mutant triosephosphate isomerase in which the active-site glutamate has been changed to aspartate. Ronald T. Raines, Eliza L. Sutton, Donald R. Straus, Walter Gilbert, and Jeremy R. Knowles (1986). Biochemistry 25, 7142–7154. [PubMed] [PDF]
  6. Enzyme relaxation in the reaction catalyzed by triosephosphate isomerase: Detection and kinetic characterization of two unliganded forms of the enzyme. Ronald T. Raines and Jeremy R. Knowles (1987). Biochemistry 26, 7014–7020. [PubMed] [PDF]
  7. Kinetics and thermodynamics of the interaction of 5-fluoro-2'-deoxyuridylate with thymidylate synthase. Daniel V. Santi, Charles S. McHenry, Ronald T. Raines, and Kathryn M. Ivanetich (1987). Biochemistry 26, 8606–8613. [PubMed] [PDF]
  8. Triosephosphate isomerase catalysis is diffusion controlled. Stephen C. Blacklow, Ronald T. Raines, Wendell A. Lim, Philip D. Zamore, and Jeremy R. Knowles (1988). Appendix: Analysis of triose phosphate equilibria in aqueous solution by 31P NMR. Wendell A. Lim, Ronald T. Raines, and Jeremy R. Knowles (1988). Biochemistry 27, 1158–1167. [PubMed] [PDF]
  9. Evolutionary optimization of the catalytic effectiveness of an enzyme. Jonathan J. Burbaum, Ronald T. Raines, W. John Albery, and Jeremy R. Knowles (1989). Biochemistry 28, 9293–9305. [PubMed] [PDF]
  10. Solvent effects on the energetics of prolyl peptide bond isomerization. Eric S. Eberhardt, Stewart N. Loh, Andrew P. Hinck, and Ronald T. Raines (1992). Journal of the American Chemical Society 114, 5437–5439. [PubMed] [PDF] [Supporting Information]
  11. Ribonuclease S-peptide as a carrier in fusion proteins. Jin-Soo Kim and Ronald T. Raines (1993). Protein Science 2, 348–356. [PubMed] [PDF]
  12. Thermodynamic origin of prolyl peptide bond isomers. Eric S. Eberhardt, Stewart N. Loh, and Ronald T. Raines (1993). Tetrahedron Letters 34, 3055–3056. [PubMed] [PDF]
  13. RNS2: A senescence-associated RNase of Arabidopsis that diverged from the S-RNases before speciation. Crispin B. Taylor, Pauline A. Bariola, Stephen B. delCardayré, Ronald T. Raines, and Pamela J. Green (1993). Proceedings of the National Academy of Sciences, U.S.A. 90, 5118–5122. [PubMed] [PDF]
  14. Bovine seminal ribonuclease produced from a synthetic gene. Jin-Soo Kim and Ronald T. Raines (1993). Journal of Biological Chemistry 268, 17392–17396. [PubMed] [PDF]
  15. Amide–amide and amide–water hydrogen bonds: Implications for protein folding and stability. Eric S. Eberhardt and Ronald T. Raines (1994). Journal of the American Chemical Society 116, 2149–2150. [PubMed] [PDF]
  16. Peptide tags for a dual affinity fusion system. Jin-Soo Kim and Ronald T. Raines (1994). Analytical Biochemistry 219, 165–166. [PubMed] [PDF]
  17. Structural determinants of enzymatic processivity. Stephen B. delCardayré and Ronald T. Raines (1994). Biochemistry 33, 6031–6037. [PubMed] [PDF]
  18. Value of general acid–base catalysis to ribonuclease A. James E. Thompson and Ronald T. Raines (1994). Journal of the American Chemical Society 116, 5467–5468. [PubMed] [PDF]
  19. Energetics of catalysis by ribonucleases: Fate of the 2',3'-cyclic phosphodiester intermediate. James E. Thompson, Fernando D. Venegas, and Ronald T. Raines (1994). Biochemistry 33, 7408–7414. [PubMed] [PDF]
  20. A misfolded but active dimer of bovine seminal ribonuclease. Jin-Soo Kim and Ronald T. Raines (1994). European Journal of Biochemistry 224, 109–114. [PubMed] [PDF]
  21. Inductive effects on the structure of proline residues. Nicholas Panasik, Jr., Eric S. Eberhardt, Arthur S. Edison, Douglas R. Powell, and Ronald T. Raines (1994). International Journal of Peptide and Protein Research 44, 262–269. [PubMed] [PDF]
  22. Dibromobimane as a fluorescent crosslinking reagent. Jin-Soo Kim and Ronald T. Raines (1995). Analytical Biochemistry 225, 174–176. [PubMed] [PDF]
  23. The extent to which ribonucleases cleave RNA. Stephen B. delCardayré and Ronald T. Raines (1995). Analytical Biochemistry 225, 176–178. [PubMed] [PDF]
  24. Structural basis for the biological activities of bovine seminal ribonuclease. Jin-Soo Kim, Josef Soucek, Josef Matousek, and Ronald T. Raines (1995). Journal of Biological Chemistry 270, 10525–10530. [PubMed] [PDF]
  25. Catalytic activity of bovine seminal ribonuclease is essential for its immunosuppressive and other biological activities. Jin-Soo Kim, Josef Soucek, Josef Matousek, and Ronald T. Raines (1995). Biochemistry Journal 308, 547–551. [PubMed] [PDF]
  26. Engineering ribonuclease A: Production, purification, and characterization of wild-type enzyme and mutants at Gln11. Stephen B. delCardayré, Marc Ribó, Erich M. Yokel, David J. Quirk, William J. Rutter, and Ronald T. Raines (1995). Protein Engineering 8, 261–273. [PubMed] [PDF]
  27. Replacing a surface loop endows ribonuclease A with angiogenic activity. Ronald T. Raines, Marian P. Toscano, David M. Nierengarten, Jeung Hoi Ha, and Robert Auerbach (1995). Journal of Biological Chemistry 270, 17180–17184. [PubMed] [PDF]
  28. Ribonuclease A: Revealing structure–function relationships with semisynthesis. June M. Messmore, Dana N. Fuchs, and Ronald T. Raines (1995). Journal of the American Chemical Society 117, 8057–8060. [PubMed] [PDF]
  29. Production of rat protein disulfide isomerase in Saccharomyces cerevisiae. Martha C. A. Laboissiere, Peter T. Chivers, and Ronald T. Raines (1995). Protein Expression and Purification 6, 700–706. [PubMed] [PDF]
  30. A residue to residue hydrogen bond mediates the nucleotide specificity of ribonuclease A. Stephen B. delCardayré and Ronald T. Raines (1995). Journal of Molecular Biology 252, 328–336. [PubMed] [PDF]
  31. Mechanism-based inactivation of ribonuclease A. Jeffrey K. Stowell, Theodore S. Widlanski, Tatiana G. Kutateladze, and Ronald T. Raines (1995). Journal of Organic Chemistry 60, 6930–6936. [PDF]
  32. The essential function of protein-disulfide isomerase is to unscramble non-native disulfide bonds. Martha C. A. Laboissiere, Stephen L. Sturley, and Ronald T. Raines (1995). Journal of Biological Chemistry 270, 28006–28009. [PubMed] [PDF]
  33. Limits to catalysis by ribonuclease A. James E. Thompson, Tatiana G. Kutateladze, Michael C. Schuster, Fernando D. Venegas, June M. Messmore, and Ronald T. Raines (1995). Bioorganic Chemistry 23, 471–481. [PDF]
  34. Mechanism of ribonuclease cytotoxicity. Jin-Soo Kim, Josef Soucek, Josef Matousek, and Ronald T. Raines (1995). Journal of Biological Chemistry 270, 31097–31102. [PubMed] [PDF]
  35. Substrate binding and turnover by the highly specific I-PpoI endonuclease. Paula K. Wittmayer and Ronald T. Raines (1996). Biochemistry 35, 1076–1083. [PubMed] [PDF]
  36. Production of human pancreatic ribonuclease in Saccharomyces cerevisiae and Escherichia coli. Marc Ribó, Stephen B. delCardayré, Ronald T. Raines, Rafael de Llorens, and Claudi M. Cuchillo (1996). Protein Expression and Purification 7, 253–261. [PubMed] [PDF]
  37. The CXXC motif: Imperatives for the formation of native disulfide bonds in the cell. Peter T. Chivers, Martha C. A. Laboissiere, and Ronald T. Raines (1996). EMBO Journal 15, 2659–2667. [PubMed] [PDF]
  38. Immunosuppressive activity of bovine seminal ribonuclease and its mode of action. Josef Soucek, Iuri Marinov, Jíri Benes, Ivan Hilbert, Josef Matousek, and Ronald T. Raines (1996). Immunobiology 195, 271–285. [PubMed] [PDF]
  39. Contribution of a tyrosine side chain to ribonuclease A catalysis and stability. Eric S. Eberhardt, Paula K. Wittmayer, Barbra M. Templer, and Ronald T. Raines (1996). Protein Science 5, 1697–1703. [PubMed] [PDF]
  40. Inductive effects on the energetics of prolyl peptide bond isomerization: Implications for collagen folding and stability. Eric S. Eberhardt, Nicholas Panasik, Jr., and Ronald T. Raines (1996). Journal of the American Chemical Society 118, 12261–12266. [PubMed] [PDF]
  41. The CXXC motif: A rheostat in the active site. Peter T. Chivers, Kenneth E. Prehoda, and Ronald T. Raines (1997). Biochemistry 36, 4061–4066. [PubMed] [PDF]
  42. Protein disulfide isomerase in spore germination and cell division. Martha C. A. Laboissiere, Stephen L. Sturley, and Ronald T. Raines (1997). Biological Chemistry 378, 431–437. [PubMed] [PDF]
  43. Green fluorescent protein as a signal for protein–protein interactions. Sang-Hyun Park and Ronald T. Raines (1997). Protein Science 6, 2344–2349. [PubMed] [PDF]
  44. Microscopic pKa Values of Escherichia coli thioredoxin. Peter T. Chivers, Kenneth E. Prehoda, Brian F. Volkman, Byung-Moon Kim, John L. Markley, and Ronald T. Raines (1997). Biochemistry 36, 14985–14991. [PubMed] [PDF]
  45. General acid/base catalysis in the active site of Escherichia coli thioredoxin. Peter T. Chivers and Ronald T. Raines (1997). Biochemistry 36, 15810–15816. [PubMed] [PDF]
  46. Ribonucleases endowed with specific toxicity for spermatogenic layers. Josef Matousek, Jin-Soo Kim, Josef Soucek, Jan Ríha, Marc Ribó, Peter A. Leland, and Ronald T. Raines (1997). Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 118, 881–888. [PubMed] [PDF]
  47. Degenerate DNA recognition by I-PpoI endonuclease. Paula K. Wittmayer, Jennifer L. McKenzie, and Ronald T. Raines (1998). Gene 206, 11–21. [PubMed] [PDF]
  48. Code for collagen's stability deciphered. Steven K. Holmgren, Kimberly M. Taylor, Lynn E. Bretscher, and Ronald T. Raines (1998). Nature 392, 666–667. [PubMed] [PDF]
  49. His···Asp catalytic dyad of ribonuclease A: Structure and function of the wild-type, D121N, and D121A enzymes. L. Wayne Schultz, David J. Quirk, and Ronald T. Raines (1998). Biochemistry 37, 8886–8898. [PubMed] [PDF]
  50. Structure and stability of the P93G variant of ribonuclease A. L. Wayne Schultz, Steven R. Hargraves, Tony A. Klink, and Ronald T. Raines (1998). Protein Science 7, 1620–1625. [PubMed] [PDF]
  51. Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments. Eric V. Shusta, Ronald T. Raines, Andreas Plückthun, and K. Dane Wittrup (1998). Nature Biotechnology 16, 773–777. [PubMed] [PDF]
  52. Coulombic forces in protein–RNA interactions: Binding and cleavage by ribonuclease A and variants at Lys7, Arg10, and Lys66. Barbra M. Fisher, Jeung-Hoi Ha, and Ronald T. Raines (1998). Biochemistry 37, 12121–12132. [PubMed] [PDF]
  53. Ribonuclease A variants with potent cytotoxic activity. Peter A. Leland, L. Wayne Schultz, Byung-Moon Kim, and Ronald T. Raines (1998). Proceedings of the National Academy of Sciences, U.S.A. 95, 10407–10412. [PubMed] [PDF]
  54. No role for pepstatin-A–sensitive proteinases in reovirus infections of L or MDCK cells. Subramanian Kothandaraman, Marcia C. Hebert, Ronald T. Raines, and Max L. Nibert (1998). Virology 251, 264–272. [PubMed] [PDF]
  55. Coulombic effects of remote subsites on the active site of ribonuclease A. Barbra M. Fisher, L. Wayne Schultz, Ronald T. Raines (1998). Biochemistry 37, 17386–17401. [PubMed] [PDF]
  56. A new remote subsite in ribonuclease A. Barbra M. Fisher, Juneko E. Grilley, Ronald T. Raines (1998). Journal of Biological Chemistry 273, 34134–34138. [PubMed] [PDF]
  57. His···Asp catalytic dyad of ribonuclease A: Conformational stability of the wild-type, D121N, D121A, and H119A enzymes. David J. Quirk, Chiwook Park, James E. Thompson, and Ronald T. Raines (1998). Biochemistry 37, 17958–17964. [PubMed] [PDF]
  58. Variants of ribonuclease inhibitor that resist oxidation. Byung-Moon Kim, L. Wayne Schultz, and Ronald T. Raines (1999). Protein Science 8, 430–434. [PubMed] [PDF]
  59. Image of CoverCOVER ARTICLE: A hyperstable collagen mimic. Steven K. Holmgren, Lynn E. Bretscher, Kimberly M. Taylor, and Ronald T. Raines (1999). Chemistry & Biology 6, 63–70. [PubMed] [PDF]
  60. His...Asp catalytic dyad of ribonuclease A: Histidine pKa values in the wild-type, D121N, and D121A enzymes. David J. Quirk and Ronald T. Raines (1999). Biophysical Journal 76, 1571–1579. [PubMed] [PDF]
  61. Extending the limits to enzymatic catalysis: Diffusion of ribonuclease A in one dimension. Bradley R. Kelemen and Ronald T. Raines (1999). Biochemistry 38, 5302–5307. [PubMed] [PDF]
  62. Structural changes to ribonuclease A and their effects on biological activity. Josef Soucek, Ronald T. Raines, Monika Haugg, Sun-Ai Raillard-Yoon, and Steven A. Benner (1999). Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 123, 103–111. [PubMed] [PDF]
  63. Hypersensitive substrate for ribonucleases. Bradley R. Kelemen, Tony A. Klink, Mark A. Behlke, Shad R. Eubanks, Peter A. Leland, and Ronald T. Raines (1999). Nucleic Acids Research 27, 3696–3701. [PubMed] [PDF]
  64. The CXXC motif: Crystal structure of an active-site variant of Escherichia coli thioredoxin. L. Wayne Schultz, Peter T. Chivers, and Ronald T. Raines (1999). Acta Crystallographica D55, 1533–1538. [PubMed] [PDF]
  65. A small-molecule catalyst of protein folding in vitro and in vivo. Kenneth J. Woycechowsky, K. Dane Wittrup, and Ronald T. Raines (1999). Chemistry & Biology 6, 871–879. [PubMed] [PDF]
  66. Chemical mechanism of DNA cleavage by the homing endonuclease I-PpoI. Stephen J. Mannino, Cara L. Jenkins, and Ronald T. Raines (1999). Biochemistry 38, 16178–16186. [PubMed] [PDF]
  67. Contribution of disulfide bonds to the conformational stability and catalytic activity of ribonuclease A. Tony A. Klink, Kenneth J. Woycechowsky, Kimberly M. Taylor, and Ronald T. Raines (2000). European Journal of Biochemistry 267, 566–572. [PubMed] [PDF]
  68. Origin of the "inactivation" of ribonuclease A at low salt concentration. Chiwook Park and Ronald T. Raines (2000). FEBS Letters 468, 199–202. [PubMed] [PDF]
  69. A ribonuclease A variant with low catalytic activity but high cytotoxicity. Lynn E. Bretscher, Richele L. Abel, and Ronald T. Raines (2000). Journal of Biological Chemistry 275, 9893-9896. [PubMed] [PDF]
  70. Prolyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegans. Lisa Friedman, Joshua J. Higgin, Gary Moulder, Robert Barstead, Ronald T. Raines, and Judith Kimble (2000). Proceedings of the National Academy of Sciences, U.S.A. 97, 4736–4741. [PubMed] [PDF]
  71. Sulfur shuffle: Modulating enzymatic activity by thiol–disulfide interchange. June M. Messmore, Steven K. Holmgren, Juneko E. Grilley, and Ronald T. Raines (2000). Bioconjugate Chemistry 11, 408–413. [PubMed] [PDF]
  72. Conformational stability is a determinant of ribonuclease A cytotoxicity. Tony A. Klink and Ronald T. Raines (2000). Journal of Biological Chemistry 275, 17463–17467. [PubMed] [PDF]
  73. Staudinger ligation: A peptide from a thioester and azide. Bradley L. Nilsson, Laura L. Kiessling, and Ronald T. Raines (2000). Organic Letters 2, 1939–1941. [PubMed] [PDF] [Supporting Information]
  74. A synapomorphic disulfide bond is critical for the conformational stability and cytotoxicity of an amphibian ribonuclease. Peter A. Leland, Kristine E. Staniszewski, Byung-Moon Kim, and Ronald T. Raines (2000). FEBS Letters 477, 203–207. [PubMed] [PDF]
  75. Genetic selection for dissociative inhibitors of designated protein–protein interactions. Sang-Hyun Park and Ronald T. Raines (2000). Nature Biotechnology 18, 847–851. [PubMed] [PDF]
  76. Decavanadate inhibits catalysis by ribonuclease A. June M. Messmore and Ronald T. Raines (2000). Archives of Biochemistry and Biophysics 381, 25–30. [PubMed] [PDF]
  77. Effect of bovine seminal ribonuclease and its various forms on bovine oocyte maturation. Tomás Slavík, Josef Matousek, Josef Fulka, and Ronald T. Raines (2000). Journal of Experimental Zoology 287, 394–399. [PubMed] [PDF]
  78. Contribution of individual disulfide bonds to the oxidative folding of ribonuclease A. Margherita Ruoppolo, Floriana Vinci, Tony A. Klink, Ronald T. Raines, and Gennaro Marino (2000). Biochemistry 39, 12033–12042. [PubMed] [PDF]
  79. Pentavalent organo-vanadates as transition state analogues for phosphoryl transfer reactions. June M. Messmore and Ronald T. Raines (2000). Journal of the American Chemical Society 122, 9911–9916. [PubMed] [PDF]
  80. A highly active immobilized ribonuclease. Rozamond Y. Sweeney, Bradley R. Kelemen, Kenneth J. Woycechowsky, and Ronald T. Raines (2000). Analytical Biochemistry 286, 312–314. [PubMed] [PDF]
  81. Image of CoverCOVER ARTICLE: Dimer formation by a "monomeric" protein. Chiwook Park and Ronald T. Raines (2000). Protein Science 9, 2026–2033. [PubMed] [PDF]
  82. Excavating an active site: The nucleobase specificity of ribonuclease A. Bradley R. Kelemen, L. Wayne Schultz, Rozamond Y. Sweeney, and Ronald T. Raines (2000). Biochemistry 39, 14,487–14,494. [PubMed] [PDF]
  83. High-yielding Staudinger ligation of a phosphinothioester and azide to form a peptide. Bradley L. Nilsson, Laura L. Kiessling, and Ronald T. Raines (2001). Organic Letters 3, 9–12. [PubMed] [PDF] [Supporting Information]
  84. Conformational stability of collagen relies on a stereoelectronic effect. Lynn E. Bretscher, Cara L. Jenkins, Kimberly M. Taylor, Michele L. DeRider, and Ronald T. Raines (2001). Journal of the American Chemical Society 123, 777–778. [PubMed] [PDF]
  85. Contribution of the active site histidine residues of ribonuclease A to nucleic acid binding. Chiwook Park, L. Wayne Schultz, and Ronald T. Raines (2001). Biochemistry 40, 4949–4956. [PubMed] [PDF]
  86. Contribution of tertiary amides to the conformational stability of collagen triple helices. Elizabeth A. Kersteen and Ronald T. Raines (2001). Biopolymers 59, 24–28. [PubMed] [PDF]
  87. Selenocysteine in native chemical ligation and expressed protein ligation. Robert J. Hondal, Bradley L. Nilsson, and Ronald T. Raines (2001). Journal of the American Chemical Society 123, 5140–5141. [PubMed] [PDF] [Supporting Information]
  88. High-level soluble production and characterization of porcine ribonuclease inhibitor. Tony A. Klink, Anna M. Vicentini, Jan Hofsteenge, and Ronald T. Raines (2001). Protein Expression and Purification 22, 174–179. [PubMed] [PDF]
  89. Cleavage of 3',5'-pyrophosphate-linked dinucleotides by ribonuclease A and angiogenin. Anwar M. Jardine, Demetres D. Leonidas, Jeremy L. Jenkins, Chiwook Park, Ronald T. Raines, K. Ravi Acharya, and Robert Shapiro (2001). Biochemistry 40, 10262–10272. [PubMed] [PDF]
  90. Quantitative analysis of the effect of salt concentration on enzymatic catalysis. Chiwook Park and Ronald T. Raines (2001). Journal of the American Chemical Society 123, 11472–11479. [PubMed] [PDF]
  91. Endowing human pancreatic ribonuclease with toxicity for cancer cells. Peter A. Leland, Kristine E. Staniszewski, Byung-Moon Kim, and Ronald T. Raines (2001). Journal of Biological Chemistry 276, 43095–43102. [PubMed] [PDF]
  92. Adjacent cysteine residues as a redox switch. Chiwook Park and Ronald T. Raines (2001). Protein Engineering 14, 939–942. [PubMed] [PDF]
  93. Translocation of a β-peptide across cell membranes. Naoki Umezawa, Michael A. Gelman, Marcia C. Haigis, Ronald T. Raines, and Samuel H. Gellman (2002). Journal of the American Chemical Society 124, 368–369. [PubMed] [PDF] [Supporting Information]
  94. The ribonucleolytic activity of angiogenin. Peter A. Leland, Kristine E. Staniszewski, Chiwook Park, Bradley R. Kelemen, and Ronald T. Raines (2002). Biochemistry 41, 1343–1350. [PubMed] [PDF]
  95. Semisynthesis of ribonuclease A using intein-mediated protein ligation. Ulrich Arnold, Matthew P. Hinderaker, and Ronald T. Raines (2002). TheScientificWorldJOURNAL 2, 1823–1827. [PubMed] [PDF]
  96. Collagen stability: Insights from NMR spectroscopic and hybrid density functional computational investigations of the effect of electronegative substituents on prolyl ring conformations. Michele L. DeRider, Steven J. Wilkens, Michael J. Waddell, Lynn E. Bretscher, Frank Weinhold, Ronald T. Raines, and John L. Markley (2002). Journal of the American Chemical Society 124, 2497–2505. [PubMed] [PDF]
  97. KFERQ sequence in ribonuclease A-mediated cytotoxicity. Marcia C. Haigis, Erin L. Kurten, Richele L. Abel, and Ronald T. Raines (2002). Journal of Biological Chemistry 277, 11576–11581. [PubMed] [PDF]
  98. Evolution of ribonuclease inhibitor by exon duplication. Marcia C. Haigis, Eric S. Haag, and Ronald T. Raines (2002). Molecular Biology and Evolution 19, 960–964. [PubMed] [PDF]
  99. Fluorescence assay for the binding of ribonuclease A to the ribonuclease inhibitor protein. Richele L. Abel, Marcia C. Haigis, Chiwook Park, and Ronald T. Raines (2002). Analytical Biochemistry 306, 100–107. [PubMed] [PDF]
  100. Staudinger ligation of α-azido acids retains stereochemistry. Matthew B. Soellner, Bradley L. Nilsson, and Ronald T. Raines (2002). Journal of Organic Chemistry 67, 4993–4996. [PubMed] [PDF] [Supporting Information]
  101. Protein prosthesis: A semisynthetic enzyme with a β-peptide reverse turn. Ulrich Arnold, Matthew P. Hinderaker, Bradley L. Nilsson, Bayard R. Huck, Samuel H. Gellman, and Ronald T. Raines (2002). Journal of the American Chemical Society 124, 8522–8523. [PubMed] [PDF] [Supporting Information]
  102. X-Ray structure of two crystalline forms of a Streptomycete ribonuclease with cytotoxic activity. Jozef Sevcik, Lubica Urbanikova, Peter A. Leland, and Ronald T. Raines (2002). Journal of Biological Chemistry 277, 47325–47330. [PubMed] [PDF]
  103. Secretory ribonucleases are internalized by a dynamin-independent endocytic pathway. Marcia C. Haigis and Ronald T. Raines (2003). Journal of Cell Science 116, 313–324. [PubMed] [PDF]
  104. Creation of a zymogen. Parit Plainkum, Stephen M. Fuchs, Suthep Wiyakrutta, and Ronald T. Raines (2003). Nature Structural Biology 10, 115–119. [PubMed] [PDF]
  105. Ribonuclease inhibitor as an intracellular sentry. Marcia C. Haigis, Erin L. Kurten, and Ronald T. Raines (2003). Nucleic Acids Research 31, 1024–1032. [PubMed] [PDF]
  106. Zinc(II)-mediated inhibition of a ribonuclease by an N-hydroxyurea nucleotide. Joshua J. Higgin, Gennady I. Yakovlev, Vladimir A. Mitkevich, Alexander A. Makarov, and Ronald T. Raines (2003). Bioorganic & Medicinal Chemistry Letters 13, 409–412. [PubMed] [PDF]
  107. Catalysis by ribonuclease A is limited by the rate of substrate association. Chiwook Park and Ronald T. Raines (2003). Biochemistry 42, 3509–3518. [PubMed] [PDF] [Supporting Information]
  108. Protein assembly by orthogonal chemical ligation methods. Bradley L. Nilsson, Robert J. Hondal, Matthew B. Soellner, and Ronald T. Raines (2003). Journal of the American Chemical Society 125, 5268–5269. [PubMed] [PDF] [Supporting Information]
  109. The CXC motif: A functional mimic of protein disulfide isomerase. Kenneth J. Woycechowsky and Ronald T. Raines (2003). Biochemistry 42, 5387–5394. [PubMed] [PDF]
  110. An electronic effect on protein structure. Matthew P. Hinderaker and Ronald T. Raines (2003). Protein Science 12, 1188–1194. [PubMed] [PDF] [Supporting Information]
  111. Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, HO-1 and NOS-2 proteins in cultured neonatal cardiomyocytes. Gary Wright, Joshua J. Higgin, Ronald T. Raines, Charles Steenbergen, and Elizabeth Murphy (2003). Journal of Biological Chemistry 278, 20235–20239. [PubMed] [PDF]
  112. Effect of 3-hydroxyproline residues on collagen stability. Cara L. Jenkins, Lynn E. Bretscher, Ilia A. Guzei, and Ronald T. Raines (2003). Journal of the American Chemical Society 125, 6422–6427. [PubMed] [PDF] [Supporting Information]
  113. Potent inhibition of ribonuclease A by oligo(vinylsulfonic acid). Bryan D. Smith, Matthew B. Soellner, and Ronald T. Raines (2003). Journal of Biological Chemistry 278, 20934–20938. [PubMed] [PDF]
  114. Protein prosthesis: A nonnatural residue accelerates folding and increases stability. Ulrich Arnold, Matthew P. Hinderaker, Jens Köditz, Ralph Golbik, Renate Ulbrich-Hofmann, and Ronald T. Raines (2003). Journal of the American Chemical Society 125, 7500–7501. [PubMed] [PDF] [Supporting Information]
  115. Image of CoverCOVER ARTICLE: Compensating effects on the cytotoxicity of ribonuclease A variants. Kimberly A. Dickson, Caroline L. Dahlberg, and Ronald T. Raines (2003). Archives of Biochemistry and Biophysics 415, 172–177. [PubMed] [PDF]
  116. Catalysis of protein folding by an immobilized small-molecule dithiol. Kenneth J. Woycechowsky, Brad A. Hook, and Ronald T. Raines (2003). Biotechnology Progress 19, 1307–1314. [PubMed] [PDF]
  117. Stereoelectroniic effects on collagen stability: The dichotomy of 4-fluoroproline diastereomers. Jonathan A. Hodges and Ronald T. Raines (2003). Journal of the American Chemical Society 125, 9263–9264. [PubMed] [PDF] [Supporting Information]
  118. Site-specific protein immobilization by Staudinger ligation. Matthew B. Soellner, Kimberly A. Dickson, Bradley L. Nilsson, and Ronald T. Raines (2003). Journal of the American Chemical Society 125, 11790–11791. [PubMed] [PDF] [Supporting Information]
  119. Contribution of active-site residues to the function of onconase, a ribonuclease with antitumoral activity. J. Eugene Lee and Ronald T. Raines (2003). Biochemistry 42, 11443–11450. [PubMed] [PDF]
  120. Comprehensive comparison of the cytotoxic activities of onconase and bovine seminal ribonuclease. J. Matousek, Josef Soucek, Tomas Slavik, Milan Tomanek, J. Eugene Lee, and Ronald T. Raines (2003). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 136, 343–356. [PubMed] [PDF]
  121. Glycosylation of onconase increases its conformational stability and toxicity for cancer cells. Byung-Moon Kim, Hana Kim, Ronald T. Raines, and Younghoon Lee (2004) Biochemical and Biophysical Research Communications 315, 976–983. [PubMed] [PDF]
  122. Pathway for polyarginine entry into mammalian cells. Stephen M. Fuchs and Ronald T. Raines (2004). Biochemistry 43, 2438–2444. [PubMed] [PDF]
  123. Identifying latent enzyme activities: Substrate ambiguity within modern bacterial sugar kinases. Brian G. Miller and Ronald T. Raines (2004). Biochemistry 43, 6387–6392. [PubMed] [PDF]
  124. Zinc(II)-mediated inhibition of ribonuclease Sa by an N-hydroxyurea nucleotide and its basis. Alexander A. Makarov, Gennady I. Yakovlev, Vladimir A. Mitkevich, Joshua J. Higgin, and Ronald T. Raines (2004). Biochemical and Biophysical Research Communications 319, 152–156. [PubMed] [PDF]
  125. Imaging the binding ability of proteins immobilized on surfaces with different orientations by using liquid crystals. Yan-Yeung Luk, Matthew L. Tingey, Kimberly A. Dickson, Ronald T. Raines, and Nicholas L. Abbott (2004). Journal of the American Chemical Society 126, 9024–9032. [PubMed] [PDF]
  126. Production of human prolyl 4-hydroxylase in Escherichia coli. Elizabeth A. Kersteen, Joshua J. Higgin, and Ronald T. Raines (2004). Protein Expression & Purification 38, 279–291. [PubMed] [PDF]
  127. Image of CoverCOVER ARTICLE: Substituted 2-azabicyclo[2.1.1]hexanes constrained proline analogs: Implications for collagen stability. Cara L. Jenkins, Guoliang Lin, Jingqi Duo, Deepa Rapolu, Ilia A. Guzei, Ronald T. Raines, and Grant R. Krow (2004). Journal of Organic Chemistry 69, 8565–8573; 71, 1754. [PubMed] [PDF] [Supporting Information]
  128. Synthetic surfaces for ribonuclease adsorption. Bryan D. Smith, Matthew B. Soellner, and Ronald T. Raines (2005). Langmuir 21, 187–190. [PubMed] [PDF]
  129. Image of CoverCOVER ARTICLE: O-Acylation of hydroxyproline residues: Effect on peptide bond isomerization and collagen stability. Cara L. Jenkins, Alexander I. McCloskey, Ilia A. Guzei, Eric S. Eberhardt, and Ronald T. Raines (2005).[ Peptide Science 80, 1–8. [PubMed] [PDF] [Supporting Information]
  130. Latent fluorophore based on the trimethyl lock. Sunil S. Chandran, Kimberly A. Dickson, and Ronald T. Raines (2005). Journal of the American Chemical Society 127, 1652–1653. [PubMed] [PDF] [Supporting Information]
  131. Binding of nonnatural 3'-nucleotides to ribonuclease A. Cara L. Jenkins, Nethaji Thiyagarajan, Rozamond Y. Sweeney, Michael P. Guy, Bradley R. Kelemen, K. Ravi Acharya, and Ronald T. Raines (2005). FEBS Journal 272, 744–755. [PubMed] [PDF]
  132. Polyarginine as a multifunctional fusion tag. Stephen M. Fuchs and Ronald T. Raines (2005). Protein Science 14, 1538–1544. [PubMed] [PDF]
  133. Peptide bond isosteres: Ester or (E)-alkene in the backbone of the collagen triple helix. Cara L. Jenkins, Melissa M. Vasbinder, Scott J. Miller, and Ronald T. Raines (2005). Organic Letters 7, 2619–2622. [PubMed] [PDF] [Supporting Information]
  134. Reconstitution of a defunct glycolytic pathway via recruitment of ambiguous sugar kinases. Brian G. Miller and Ronald T. Raines (2005). Biochemistry 44, 10776–10783. [PubMed] [PDF]
  135. Catalysis of protein disulfide bond isomerization in a homogeneous substrate. Elizabeth A. Kersteen, Seth R. Barrows, and Ronald T. Raines (2005). Biochemistry 44, 12168–12178. [PubMed] [PDF]
  136. Image of CoverCOVER ARTICLE: Disruption of shape-complementarity markers to create cytotoxic variants of ribonuclease A. Thomas J. Rutkoski, Erin L. Kurten, Julie C. Mitchell, and Ronald T. Raines (2005). Journal of Molecular Biology 354, 41–54. [PubMed] [PDF]
  137. Stereoelectronic and steric effects in the collagen triple helix: Toward a code for strand association. Jonathan A. Hodges and Ronald T. Raines (2005). Journal of the American Chemical Society 127, 15923–15932. [PubMed] [PDF] [Supporting Information]
  138. Cytotoxicity of bovine seminal ribonuclease: Monomer versus dimer. J. Eugene Lee and Ronald T. Raines (2005). Biochemistry 44, 15760–15767. [PubMed] [PDF]
  139. Image of CoverCOVER ARTICLE: Stereoelectronic effects on polyproline conformation. Jia-Cherng Horng and Ronald T. Raines (2006). Protein Science 15, 74–83. [PubMed] [PDF]
  140. Self-assembly of synthetic collagen triple helices. Frank W. Kotch and Ronald T. Raines (2006). Proceedings of the National Academy of Sciences, U.S.A. 103, 3028–3033. [PubMed] [PDF] [Supporting Information]
  141. Semisynthesis and characterization of mammalian thioredoxin reductase. Brian Eckenroth, Katharine Harris, Anton A. Turanov, Vadim N. Gladyshev, Ronald T. Raines, and Robert J. Hondal (2006). Biochemistry 45, 5158–5170. [PubMed] [PDF]
  142. Contrast agents for magnetic resonance imaging synthesized with ring-opening metathesis polymerization. Matthew J. Allen, Ronald T. Raines, and Laura L. Kiessling. Journal of the American Chemical Society 128, 6534–6535. [PubMed] [PDF] [Supporting Information]
  143. Fluorogenic label for biomolecular imaging. Luke D. Lavis, Tzu-Yuan Chao, and Ronald T. Raines (2006). ACS Chemical Biology 1, 252–260. [PubMed] [PDF] [Supporting Information] [Movie]
  144. Reciprocity of steric and stereoelectronic effects in the collagen triple helix. Matthew D. Shoulders, Jonathan A. Hodges, and Ronald T. Raines (2006). Journal of the American Chemical Society 128, 8112–8113. [PubMed] [PDF] [Supporting Information]
  145. Reaction mechanism and kinetics of the traceless Staudinger ligation. Matthew B. Soellner, Bradley L. Nilsson, and Ronald T. Raines (2006). Journal of the American Chemical Society 128, 8820–8828. [PubMed] [PDF] [Supporting Information]
  146. Latent red and blue fluorophores based on the trimethyl lock. Luke D. Lavis, Tzu-Yuan Chao, and Ronald T. Raines (2006). ChemBioChem 7, 1151–1154. [PubMed] [PDF]
  147. Genetic selection for critical residues in ribonucleases. Bryan D. Smith and Ronald T. Raines (2006). Journal of Molecular Biology 362, 459–478. [PubMed] [PDF] [SuppInfo1] [SuppInfo2] [Movie]
  148. Characterization of protein immobilization at silver surfaces by near-edge X-ray absorptive fine structure spectroscopy. Xiaosong Liu, Chang-Hyun Jang, Fan Zheng, Astrid Jürgensen, J. D. Denlinger, Kimberly A. Dickson, Ronald T. Raines, Nicholas L. Abbott, and F. J. Himpsel (2006). Langmuir 22, 7719–7725. [PubMed] [PDF]
  149. Reactivity of intein thioesters: Appending a functional group to a protein. Jeet Kalia and Ronald T. Raines (2006). ChemBioChem 7, 1375–1383. [PubMed] [PDF]
  150. Synthesis and characterization of a novel class of reducing agents that are highly neuroprotective for retinal ganglion cells. Christopher R. Schlieve, Annie Tam, Bradley L. Nilsson, Christopher J. Lieven, Ronald T. Raines, and Leonard A. Levin (2006). Experimental Eye Research 83, 1252–1259. [PubMed] [PDF]
  151. Energetics of an n->π* interaction that impacts protein structure. Jonathan A. Hodges and Ronald T. Raines (2006). Organic Letters 8, 4695–4697. [PubMed] [PDF] [Supporting Information]
  152. Macrocyclic scaffold for the collagen triple helix. Jia-Cherng Horng, Andrew J. Hawk, Qian Zhao, Eric S. Benedict, and Steven D. Burke, and Ronald T. Raines (2006). Organic Letters 8, 4735–4738. [PubMed] [PDF] [Supporting Information]
  153. A ribonuclease zymogen activated by the NS3 protease of the hepatitis C virus. R. Jeremy Johnson, Shawn R. Lin, and Ronald T. Raines (2006). FEBS Journal 273, 5457–5465. [PubMed] [PDF]
  154. Staudinger ligation of peptides at non-glycyl residues. Matthew B. Soellner, Annie Tam, and Ronald T. Raines (2006). Journal of Organic Chemistry 71, 9824–9830. [PubMed] [PDF]
  155. Is glycine a surrogate for a D-amino acid in the collagen triple helix? Jia-Cherng Horng, Frank W. Kotch, and Ronald T. Raines (2007). Protein Science 16, 208–215. [PubMed] [PDF]
  156. Salicylaldimine ruthenium alkylidene complexes: Metathesis catalysts tuned for protic solvents. Joseph B. Binder, Ilia A. Guzei, and Ronald T. Raines (2007). Advanced Synthesis & Catalysis 349, 395–404. [PubMed] [PDF]
  157. Multilayered films fabricated from an oligoarginine-conjugated protein promote efficient surface-mediated protein transduction. Christopher M. Jewell, Stephen M. Fuchs, Ryan M. Flessner, Ronald T. Raines, and David M. Lynn (2007). Biomacromolecules 8, 857–863. [PubMed] [PDF]
  158. Arginine grafting to endow cell-permeability. Stephen M. Fuchs and Ronald T. Raines (2007). ACS Chemical Biology 2, 167–170. [PubMed] [PDF] [Supporting Information]
  159. Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein. R. Jeremy Johnson, Jason G. McCoy, Craig A. Bingman, George N. Phillips, Jr., and Ronald T. Raines (2007). Journal of Molecular Biology 368, 434–449. [PubMed] [PDF]
  160. General method for site-specific protein immobilization by Staudinger ligation. Jeet Kalia, Nicholas L. Abbott, and Ronald T. Raines (2007). Bioconjugate Chemistry 18, 1064–1069. [PubMed] [PDF]
  161. Genetic selection to reveal the role of a buried, conserved polar residue. R. Jeremy Johnson, Shawn R. Lin, and Ronald T. Raines (2007). Protein Science 16, 1609–1616. [PubMed] [PDF]
  162. Tuning the pKa of fluorescein to optimize binding assays. Luke D. Lavis, Thomas J. Rutkoski, and Ronald T. Raines (2007). Analytical Chemistry 79, 6775–6782. [PubMed] [PDF] [Supporting Information]
  163. Cytotoxic ribonucleases: The dichotomy of Coulombic forces. R. Jeremy Johnson, Tzu-Yuan Chao, Luke D. Lavis, and Ronald T. Raines (2007). Biochemistry 46, 10308–10316. [PubMed] [PDF]
  164. Using measurements of anchoring energies of liquid crystals on surfaces to quantify protein capture by immobilized ligands. Thimmaiah Govindaraju, Paul J. Bertics, Ronald T. Raines, and Nicholas J. Abbott (2007). Journal of the American Chemical Society 129, 11223–11231. [PubMed] [PDF] [Supporting Information]
  165. Water-soluble phosphinothiols for traceless Staudinger ligation and integration with expressed protein ligation. Annie Tam, Matthew B. Soellner, and Ronald T. Raines (2007). Journal of the American Chemical Society 129, 11421–11430. [PubMed] [PDF] [Supporting Information]
  166. Protein prosthesis: 1,5-Disubstituted[1,2,3]triazoles as cis-peptide bond surrogates. Annie Tam, Ulrich Arnold, Matthew B. Soellner, and Ronald T. Raines (2007). Journal of the American Chemical Society 129, 12670–12671. [PubMed] [PDF] [Supporting Information]
  167. Catalysis of imido group hydrolysis in a maleimide conjugate. Jeet Kalia and Ronald T. Raines (2007). Bioorganic & Medicinal Chemistry Letters 17, 6286–6289. [PubMed] [PDF]
  168. Olefin metathesis in homogeneous aqueous media catalyzed by conventional ruthenium catalysts. Joseph B. Binder, Jacqueline J. Blank, and Ronald T. Raines (2007). Organic Letters 9, 4885–4888. [PubMed] [PDF] [Supporting Information]
  169. Intraspecies regulation of ribonucleolytic activity. R. Jeremy Johnson, Luke D. Lavis, and Ronald T. Raines (2007). Biochemistry 46, 13131–13140. [PubMed] [PDF] [Supporting Information]
  170. Image of CoverCOVER ARTICLE: Increasing the potency of a cytotoxin with an arginine graft. Stephen M. Fuchs, Thomas J. Rutkoski, Vanessa M. Kung, Ryan T. Groeschl, and Ronald T. Raines (2007). Protein Engineering, Design & Selection 20, 505–509. [PubMed] [PDF]
  171. Structural basis for catalysis by onconase. J. Eugene Lee, Euiyoung Bae, Craig A. Bingman, George N. Phillips, Jr., and Ronald T. Raines (2008). Journal of Molecular Biology. 375, 165–177. [PubMed] [PDF]
  172. Trimethyl lock: A stable chromogenic substrate for esterases. Michael N. Levine, Luke D. Lavis, and Ronald T. Raines (2008). Molecules 13, 204–211. [PubMed] [PDF]
  173. 4-Chloroprolines: Synthesis, conformational analysis, and effect on the collagen triple helix. Matthew D. Shoulders, Ilia A. Guzei, and Ronald T. Raines (2008). Biopolymers 89, 443–454. [PubMed] [PDF]
  174. Stabilization of the collagen triple helix by O-methylation of hydroxyproline residues. Frank W. Kotch, Ilia A. Guzei, and Ronald T. Raines (2008). Journal of the American Chemical Society 130, 2952–2953. [PubMed] [PDF] [Supporting Information]
  175. Electronic and steric effects on the rate of the traceless Staudinger ligation. Annie Tam, Matthew B. Soellner, and Ronald T. Raines (2008). Organic & Biomolecular Chemistry 6, 1173–1175. [PubMed] [PDF] [Supporting Information]
  176. Genetic selection for peptide inhibitors of angiogenin. Bryan D. Smith and Ronald T. Raines (2008). Protein Engineering, Design & Selection 21, 289–294. [PubMed] [PDF] [Supporting Information]
  177. Self-assembled collagen-like peptide fibers as templates for metallic nanowires. Daniel Gottlieb, Stephen A. Morin, Song Jin, and Ronald T. Raines (2008). Journal of Materials Chemistry 18, 3865–3870. [PubMed] [PDF] [Supporting Information]
  178. Practical syntheses of 4-fluoroprolines. Mukund S. Chorghade, Debendra K. Mohapatra, Gokarneswar Sahoo, Mukund K. Gurjar, Manish V. Mandlecha, Nitin Bhoite, Santosh Moghe, and Ronald T. Raines (2008). Journal of Fluorine Chemistry 129, 781–784. [PubMed] [PDF]
  179. Conformational preferences of substrates for human prolyl 4-hydroxylase. Kelly L. Gorres, Ram Edupuganti, Grant R. Krow, and Ronald T. Raines (2008). Biochemistry 47, 9447–9455. [PubMed] [PDF]
  180. Hydrolytic stability of hydrazones and oximes. Jeet Kalia and Ronald T. Raines (2008).Angewandte Chemie International Edition 47, 7523–7526. [PubMed] [PDF] [Supporting Information]
  181. A highly sensitive fluorogenic probe for cytochrome P450 activity in live cells. Melissa M. Yatzeck, Luke D. Lavis, Tzu-Yuan Chao, Sunil S. Chandran, and Ronald T. Raines (2008). Bioorganic & Medicinal Chemistry Letters 18, 5864–5866. [PubMed] [PDF] [Supporting Information]
  182. Interaction of onconase with the human ribonuclease inhibitor protein. Rebecca F. Turcotte and Ronald T. Raines (2008). Biochemical and Biophysical Research Communications 377, 512–514. [PubMed] [PDF]
  183. Design and characterization of an HIV-specific ribonuclease zymogen. Rebecca F. Turcotte and Ronald T. Raines (2008).AIDS Research and Human Retroviruses 24, 1357–1363. [PubMed] [PDF]
  184. Coulombic effects on the traceless Staudinger ligation in water. Annie Tam and Ronald T. Raines (2009). Bioorganic & Medicinal Chemistry 17, 1055–1063. [PubMed] [PDF] [Supporting Information]
  185. Simple chemical transformation of lignocellulosic biomass into furanics for fuels and chemicals. Joseph B. Binder and Ronald T. Raines (2009). Journal of the American Chemical Society 131, 1979–1985. [PubMed] [PDF] [Supporting Information]
  186. Direct and continuous assay for prolyl 4-hydroxylase. Kelly L. Gorres and Ronald T. Raines (2009). Analytical Biochemistry 386, 181–185. [PubMed] [PDF]
  187. Image of CoverCOVER ARTICLE: A phosphine-mediated conversion of azides into diazo compounds. Eddie L. Myers and Ronald T. Raines (2009). Angewandte Chemie International Edition 48, 2359–2363. [PubMed] [PDF] [ [Supporting Information]
  188. Ribonuclease inhibitor regulates neovascularization by human angiogenin. Kimberly A. Dickson, Dong-Ku Kang, Young Sam Kwon, Jae Chan Kim, Peter A. Leland, Byung-Moon Kim, Soo-Ik Chang, and Ronald T. Raines (2009). Biochemistry 48, 3804–3806. [PubMed] [PDF] [Supporting Information]
  189. Nature of amide carbonyl–carbonyl interactions in proteins. Amit Choudhary, Deepa Gandla, Grant R. Krow, and Ronald T. Raines (2009). Journal of the American Chemical Society 131, 7244–7246. [PubMed] [PDF] [Supporting Information]
  190. Silencing an inhibitor unleashes a cytotoxic enzyme. Kimberly A. Dickson and Ronald T. Raines (2009). Biochemistry 48, 5051–5053. [PubMed] [PDF] [Supporting Information]
  191. ROMP from ROMP: A new approach to graft copolymer synthesis. Matthew J. Allen, Kittikhun Wangkanont, Ronald T. Raines, and Laura L. Kiessling (2009). Macromolecules 42 , 4023–4027. [PubMed] [PDF] [Supporting Information]
  192. Onconase cytotoxicity relies on the distribution of its positive charge. Rebecca F. Turcotte, Luke D. Lavis, and Ronald T. Raines (2009). FEBS Journal 276, 4270–4281. [PubMed] [PDF] [Supporting Information]
  193. Origin of the stability conferred upon collagen by fluorination. Matthew D. Shoulders, Kimberli J. Kamer, and Ronald T. Raines (2009). Bioorganic & Medicinal Chemistry Letters 19, 3859–3862. [PubMed] [PDF] [Supporting Information]
  194. Fluorogenic affinity label for the facile, rapid imaging of proteins in live cells. Rex W. Watkins, Luke D. Lavis, Vanessa M. Kung, Georgyi V. Los, and Ronald T. Raines (2009). Organic & Biomolecular Chemistry 7, 969–975. [PubMed] [PDF] [Supporting Information]
  195. Structure and function of Bacillus subtilis YphP, a prokaryotic disulfide isomerase with a CXC catalytic motif. Urszula Derewenda, Tomasz Boczek, Kelly L. Gorres, Minmin Yu, Li-wei Hung, David Cooper, Andrzej Joachimiak, Ronald T. Raines, and Zygmunt S. Derewenda (2009). Biochemistry 48, 8664–8671. [PubMed] [PDF]
  196. 5(6)-anti-Substituted-2-azabicyclo[2.1.1]hexanes: A nucleophilic displacement route. Grant R. Krow, Ram Edupuganti, Deepa Gandla, Amit Choudhary, Guoliang Lin, Philip E. Sonnet, Charles DeBrosse, Charles W. Ross, III, Kevin C. Cannon, and Ronald T. Raines (2009). Journal of Organic Chemistry 74, 8232–8242. [PubMed] [PDF]
  197. Stringency of the 2-His–1-Asp active-site motif in prolyl 4-hydroxylase. Kelly L. Gorres, Khian Hong Pua, and Ronald T. Raines (2009). PLoS ONE 4, e7635. [PubMed] [PDF]
  198. 1,9-Bis(2-pyridyl)-1,2,8,9-tetrathia-5-oxanonane. Jeet Kalia and Ronald T. Raines (2009). Molbank, M642. [PubMed] [PDF]
  199. Stereoelectronic and steric effects in side chains preorganize a protein main chain. Matthew D. Shoulders, Kenneth A. Satyshur, Katrina T. Forest, and Ronald T. Raines (2010). Proceedings of the National Academy of Sciences, U.S.A. 107, 559–564. [PubMed] [PDF] [Supporting Information]
  200. Fermentable sugars by chemical hydrolysis of biomass. Joseph B. Binder and Ronald T. Raines (2010). Proceedings of the National Academy of Sciences, U.S.A. 107, 4516–4521. [PubMed] [PDF] [Supporting Information]
  201. n→π* Interaction and n)(π Pauli repulsion are antagonistic for protein stability. Charles E. Jakobsche, Amit Choudhary, Scott J. Miller, and Ronald T. Raines (2010). Journal of the American Chemical Society 132, 6651–6653. [PubMed] [PDF] [Supporting Information]
  202. Image of CoverCOVER ARTICLE: Mechanistic insights on the conversion of sugars into 5-hydroxymethylfurfural. Joseph B. Binder, Anthony V. Cefali, Jacqueline J. Blank, and Ronald T. Raines (2010). Energy & Environmental Science 3, 765–771. [PDF]
  203. A stereoelectronic effect in prebiotic nucleotide synthesis. Amit Choudhary, Kimberli J. Kamer, Matthew W. Powner, John D. Sutherland, and Ronald T. Raines (2010). ACS Chemical Biology 5, 655–657. [PubMed] [PDF]
  204. n→π* Interactions in proteins. Gail J. Bartlett, Amit Choudhary, Ronald T. Raines, and Derek N. Woolfson (2010). Nature Chemical Biology 6, 615–620. [PubMed] [PDF] [Supporting Information]
  205. Modulation of an n→π* interaction with α-fluoro groups. Amit Choudhary, Charles G. Fry, and Ronald T. Raines (2010). ARKIVOC 251–262. [PDF]
  206. The aberrance of the 4S diastereomer of 4-hydroxyproline. Matthew D. Shoulders, Frank W. Kotch, Amit Choudhary, Ilia A. Guzei, and Ronald T. Raines (2010). Journal of the American Chemical Society 132, 10857–10865. [PubMed] [PDF] [Supporting Information]
  207. Antitumor activity of ribonuclease multimers created by site-specific covalent tethering. Thomas J. Rutkoski, John A. Kink, Laura E. Strong, Christine I. Schilling, and Ronald T. Raines (2010). Bioconjugate Chemistry 21, 1691–1702. [PubMed] [PDF] [Supporting Information]
  208. Image of CoverCOVER ARTICLE: Synthesis of furfural from xylose and xylan. Joseph B. Binder, Jacqueline J. Blank, Anthony V. Cefali, and Ronald T. Raines (2010). ChemSusChem 3, 1268–1272. [PubMed] [PDF]
  209. Oligomers of a 5-carboxy-methanopyrrolidine β-amino acid. A search for order. Grant R. Krow, Nian Liu, Matthew Sender, Guoliang Lin, Ryan Centafont, Philip E. Sonnet, Charles DeBrosse, Charles W. Ross, III, Patrick J. Carroll, Matthew D. Shoulders, and Ronald T. Raines (2010). Organic Letters 12, 5438–5441. [PubMed] [PDF] [Supporting Information]
  210. Cellular uptake of ribonuclease A relies on anionic glycans. Tzu-Yuan Chao, Luke D. Lavis, and Ronald T. Raines (2010). Biochemistry 49, 10666–10673. [PubMed] [PDF]
  211. Ribonuclease S redux. Rex W. Watkins, Ulrich Arnold, and Ronald T. Raines (2011). Chemical Communications 47, 973–975. [PubMed] [ [PDF] [Supporting Information]
  212. Functional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of bovine pancreatic ribonuclease. Nethaji Thiyagarajan, Bryan D. Smith, Ronald T. Raines, and K. Ravi Acharya (2011). FEBS Journal 278, 541–549. [PubMed] [PDF] [Supporting Information]
  213. Disruption and formation of surface salt bridges are coupled to DNA binding by integration host factor (IHF): A computational analysis. Liang Ma, Nadia K. Sundlass, Ronald T. Raines, and Qiang Cui (2011). Biochemistry 50, 266–275. [PubMed] [PDF]
  214. Synthesis and utility of fluorogenic acetoxymethyl ethers. Luke D. Lavis, Tzu-Yuan Chao, and Ronald T. Raines (2011). Chemical Science 2, 521–530. [PubMed] [PDF] [Supporting Information]
  215. Conversion of fructose into 5-(hydroxymethyl)furfural in sulfolane. Benjamin R. Caes and Ronald T. Raines (2011). ChemSusChem 4, 353–356. [PubMed] [PDF] [Supporting Information]
  216. Tunable, post-translational hydroxylation of collagen domains in Escherichia coli. Daniel M. Pinkus, Sheng Ding, Ronald T. Raines, and Annelise E. Barron (2011). ACS Chemical Biology 6, 320–324. [PubMed] [PDF] [Supporting Information]
  217. Potentiation of ribonuclease cytotoxicity by a poly(amidoamine) dendrimer. Gregory A. Ellis, Megan L. Hornung, and Ronald T. Raines (2011). Bioorganic & Medicinal Chemistry Letters 21, 2756–2758. [PubMed] [PDF] [Supporting Information]
  218. Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides. Amit Choudhary, Khian Hong Pua, and Ronald T. Raines (2011). Amino Acids 41, 181–186. [PubMed] [PDF]
  219. Synthesis of conformationally constrained 5-fluoro- and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche- and anti-3-fluoro- and 3-hydroxypyrrolidines. Grant R. Krow, Matthew D. Shoulders, Ram Edupuganit, Deepa Gandla, Fang Yu, Matthew Sender, Philip E. Sonnet, Michael J. Zdilia, Charles DeBrosse, Kevin C. Cannon, Charles W. Ross, III, Amit Choudhary, and Ronald T. Raines (2011). Journal of Organic Chemistry 76, 3626–3634. [PubMed] [PDF] [Supporting Information]
  220. Image of CoverCOVER ARTICLE: Signature of n→π* interactions in α-helices. Amit Choudhary and Ronald T. Raines (2011). Protein Science 20, 1077–1081. [PubMed] [PDF] [Supporting Information]
  221. Interstrand dipole–dipole interactions can stabilize the collagen triple helix. Matthew D. Shoulders and Ronald T. Raines (2011). Journal of Biological Chemistry 286, 22905–22912. [PubMed] [PDF] [Supporting Information]
  222. Site-specific PEGylation endows a mammalian ribonuclease with antitumor activity. Thomas J. Rutkoski, John A. Kink, Laura E. Strong, and Ronald T. Raines (2011). Cancer Biology & Therapy 12, 208–214. [PubMed] [PDF] [Supporting Information]
  223. Site-specific folate conjugation to a cytotoxic protein. Bryan D. Smith, Joshua J. Higgin, and Ronald T. Raines (2011). Bioorganic & Medicinal Chemistry Letters 21, 5029–5032. [PubMed] [PDF] [Supporting Information]
  224. Sensitive fluorogenic substrate for alkaline phosphatase. Michael N. Levine and Ronald T. Raines (2011). Analytical Biochemistry 418, 247–252. [PubMed] [PDF]
  225. Mechanism of ribonuclease A endocytosis: Analogies to cell-penetrating peptides. Tzu-Yuan Chao and Ronald T. Raines (2011). Biochemistry 50, 7835–7841. [PubMed] [PDF]
  226. An n→π* interaction in aspirin: Implications for structure and reactivity. Amit Choudhary, Kimberli J. Kamer, and Ronald T. Raines (2011). Journal of Organic Chemistry 76, 7933–7937. [PubMed] [PDF] [Supporting Information]
  227. Separable fluorous ionic liquids for the dissolution and saccharification of cellulose. Benjamin R. Caes, Joseph B. Binder, Jacqueline J. Blank, and Ronald T. Raines (2011). Green Chemistry 13, 2719–2722. [PDF] [Supporting Information]
  228. Arginine residues are more effective than lysine residues in eliciting the cellular uptake of onconase. Nadia K. Sundlass and Ronald T. Raines (2011). Biochemistry 50, 10293–10299. [PubMed] [PDF]
  229. A conserved interaction with the chromophore of fluorescent proteins. Amit Choudhary, Kimberli J. Kamer, and Ronald T. Raines (2012). Protein Science 21, 171–177. [PubMed] [PDF] [Supporting Information]
  230. tRNA Ligase catalyzes the GTP-dependent ligation of RNA with 3′-phosphate and 5′-hydroxyl termini. Kevin K. Desai and Ronald T. Raines (2012). Biochemistry 51, 1333–1335. [PubMed] [PDF] [Supporting Information]
  231. Boronate-mediated biologic delivery. Gregory A. Ellis, Michael J. Palte, and Ronald T. Raines (2012). Journal of the American Chemical Society 134, 3631–3634. [PubMed] [PDF] [Supporting Information]
  232. A potent, versatile disulfide-reducing agent from aspartic acid. John C. Lukesh, III, Michael J. Palte, and Ronald T. Raines (2012). Journal of the American Chemical Society 134, 4057–4059. [PubMed] [PDF] [Supporting Information]
  233. Interaction of nucleic acids with the glycocalyx. Michael J. Palte and Ronald T. Raines (2012). Journal of the American Chemical Society 134, 6218–6223. [PubMed] [PDF] [Supporting Information]
  234. Ribonuclease-activated cancer prodrug. Gregory A. Ellis, Nicholas A. McGrath, Michael J. Palte, and Ronald T. Raines (2012). ACS Medicinal Chemistry Letters 3, 268–272. [PubMed] [PDF] [Supporting Information]
  235. Synthesis of 5-fluoro- and 5-hydroxymethanoprolines via lithiation of N-BLOC-methanopyrrolidines. Constrained Cγ-exo and Cγ-endo Flp and Hyp conformer mimics. Grant R. Krow, Matthew D. Shoulders, Ram Edupuganti, Deepa Gandla, Fang Yu, Philip E. Sonnet, Matthew Sender, Amit Choudhary, Charles DeBrosse, Charles W. Ross, III, Patrick Carroll, and Ronald T. Raines (2012). Journal of Organic Chemistry 77, 5331–5344. [PubMed] [PDF] [Supporting Information
  236. Conversion of biomass to sugars via ionic liquid hydrolysis: Process synthesis and economic evaluation. S. Murat Sen, Joseph B. Binder, Ronald T. Raines, and Christos T. Maravelias (2012). Biofuels, Bioproducts & Biorefining 6, 444–452. [PDF]
  237. Peptides that anneal to natural collagen in vitro and ex vivo. Sayani Chattopadhyay, Christopher J. Murphy, Jonathan F. McAnulty, and Ronald T. Raines (2012). Organic & Biomolecular Chemistry 10, 5892–5897. [PubMed] [PDF]
  238. Image of CoverCOVER ARTICLE: Ribonucleoside 3′-phosphates as pro-moieties for an orally administrated drug. Michael J. Palte, Amy K. F. Davis, Nicholas A. McGrath, and Ronald T. Raines (2012). ChemMedChem 7, 1361–1364. [PubMed] [PDF] [Supporting Information]
  239. Diazo-compounds as highly tunable reactants in 1,3-dipolar cycloaddition reactions with cycloalkynes. Nicholas A. McGrath and Ronald T. Raines (2012). Chemical Science 3, 3237–3240. [PubMed] [PDF] [Supporting Information]
  240. Organocatalytic conversion of cellulose into a platform chemical. Benjamin R. Caes, Michael J. Palte, and Ronald T. Raines (2013). Chemical Science 4, 196–199. PubMed [PDF] [Supporting Information]
  241. Fluorogenic label to quantify the cytosolic delivery of macromolecules. Tzu-Yuan Chao and Ronald T. Raines (2013). Molecular BioSystems 9, 339–342. [PubMed] [PDF]
  242. A novel fully human antitumor immunoRNase resistant to the RNase inhibitor. Gennaro Riccio, Chiara D'Avino, Ronald T. Raines, and Claudia De Lorenzo (2013). Protein Engineering, Design & Selection 26, 243–248. [PubMed] [PDF]
  243. Protein prosthesis: β-Peptides as reverse-turn surrogates. Ulrich Arnold, Bayard R. Huck, Samuel H. Gellman, and Ronald T. Raines (2013). Protein Science 22, 274–279. [PubMed] [PDF] [ Supporting Information]
  244. Intimate interactions with carbonyl groups: Dipole–dipole or nπ*? Kimberli J. Kamer, Amit Choudhary, and Ronald T. Raines (2013). Journal of Organic Chemistry 78, 2099–2103. [PubMed] [PDF] [Supporting Information]
  245. Structures of the noncanonical RNA ligase RtcB reveal the mechanism of histidine guanylylation. Kevin K. Desai, Craig A. Bingman, George N. Phillips, Jr., and Ronald T. Raines (2013). Biochemistry 52, 2518–2525. [PubMed] [PDF] [Supporting Information]
  246. Fluorogenic probe for constitutive cellular endocytosis. Michael N. Levine, Trish T. Hoang, and Ronald T. Raines (2013). Chemistry & Biology 20, 614–618. [PDF] [Supporting Information]
  247. Pyramidalization of a carbonyl C atom in (2S)-N-(selenoacteyl)proline methyl ester. Ilia A. Guzei, Amit Choudhary, and Ronald T. Raines (2013). Acta Crystallographica E69, o805–o806. [PubMed] [PDF]
  248. nπ Interactions of amides and thioamides: Implications for protein stability. Robert W. Newberry, Brett VanVeller, and Ronald T. Raines (2013). Journal of the American Chemical Society 135, 7843–7846. [PubMed]
  249. Bioavailable affinity label for collagen prolyl 4-hydroxylase. James D. Vasta, Joshua J. Higgin, Elizabeth A. Kersteen, and Ronald T. Raines (2013). Bioorganic & Medicinal Chemistry 21, 3597–3601. [PubMed]
  250. Human ribonuclease with a pendant poly(ethylene glycol) inhibits tumor growth in mice. Thomas J. Rutkoski, John A. Kink, Laura E. Strong, and Ronald T. Raines (2013). Translational Oncology 6, 392–397. [PubMed] [PDF]
  251. nπ Interactions in poly(lactic acid) suggest a role in protein folding. Robert W. Newberry and Ronald T. Raines (2013). Chemical Communications 49, 7699–7701. [PubMed] [PDF]
  252. An nπ* interaction reduces the electrophilicity of the acceptor carbonyl group. Amit Choudhary, Charles G. Fry, Kimberli J. Kamer, and Ronald T. Raines (2013). Chemical Communications 49, 8166–8168. [PubMed] [PDF] [Supporting Information]
  253. Contribution of electrostatics to the binding of pancreatic-type ribonucleases to membranes. Nadia K. Sundlass, Chelcie H. Eller, Qiang Cui, and Ronald T. Raines (2013). Biochemistry 52, 6304–6312. [PubMed] [PDF]
  254. Facile chemical functionalization of proteins through intein-linked yeast display. Carrie J. Marshall, Nitin Agarwal, Jeet Kalia, Vanessa A. Grosskopf, Nicholas A. McGrath, Ronald T. Raines, and Eric V. Shusta (2013). Bioconjugate Chemistry 24, 1634–1644. [PubMed] [PDF] [Supporting Information]
  255. Conversion of azides into diazo compounds in water. Ho-Hsuan Chou and Ronald T. Raines (2013). Journal of the American Chemical Society 135, 14936–14939. [PubMed] [PDF] [Supporting Information]
  256. A divalent protecting group for benzoxaboroles. Brett VanVeller, Matthew R. Aronoff, and Ronald T. Raines (2013). RSC Advances 3, 21331–21333. [PubMed] [PDF] [Supporting Information]
  257. Simulated moving bed chromatography: Separation and recovery of sugars and ionic liquid from biomass hydrolysates. Benjamin R. Caes, Thomas R. Van Oosbree, Fachuang Lu, John Ralph, Christos T. Maravelias, and Ronald T. Raines (2013). ChemSusChem 6, 2083–2089. [PubMed] [PDF] [Supporting Information]
  258. Image of CoverCOVER ARTICLE: Thiols and selenols as electron-relay catalysts for disulfide-bond reduction. John C. Lukesh, III, Brett VanVeller, and Ronald T. Raines (2013). Angewandte Chemie International Edition 52, 12901–12904. [PubMed] [PDF] [Supporting Information]
  259. Detection of boronic acids through excited-state intramolecular proton-transfer fluorescence. Matthew R. Aronoff, Brett VanVeller, and Ronald T. Raines (2013). Organic Letters 15, 5382–5385. [PubMed] [PDF] [Supporting Information]
  260. Interplay of hydrogen bonds and nπ* interactions in proteins. Gail J. Bartlett, Robert W. Newberry, Brett VanVeller, Ronald T. Raines, and Derek N. Woolfson (2013). Journal of the American Chemical Society 135, 18682–18688. [PubMed] [PDF] [Supporting Information]
  261. Effects of a second-generation human anti-ErbB2 immunoRNase on trastuzumab-resistant tumors and cardiac cells. Chiara D'Avino, Rolando Paciello, Gennaro Riccio, Melina Coppola, Paolo Laccetti, Nicola Maurea, Ronald T. Raines, and Claudia De Lorenzo (2014). Protein Engineering, Design & Selection 27, 83–88. [PubMed] [PDF]
  262. Signatures of nπ* interactions in proteins. Robert W. Newberry, Gail J. Bartlett, Brett VanVeller, Derek N. Woolfson, and Ronald T. Raines (2014). Protein Science 23, 284–288. [PubMed] [PDF] [Supporting Information]
  263. A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation. Kevin K. Desai, Chin L. Cheng, Craig A. Bingman, George N. Phillips, Jr., and Ronald T. Raines (2014). Nucleic Acids Research 42, 3931–3942. [PubMed[PDF] [Supporting Information]
  264. Image of CoverCOVER ARTICLE: Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles. Lauren M. Zasadil, Kristen A. Andersen, Dabin Yeum, Gabrielle B. Rocque, Lee G. Wilke, Amye J. Tevaarwerk, Ronald T. Raines, Mark E. Burkard, and Beth A. Weaver (2014). Science Translational Medicine 6, 229ra43. [PubMed] [PDF] [Supporting Information]
  265. A key nπ* interaction in N-acyl homoserine lactones. Robert W. Newberry and Ronald T. Raines (2014). ACS Chemical Biology 9, 880–883. [PubMed] [PDF] [Supporting Information]
  266. nπ* Interactions engender chirality in carbonyl groups. Amit Choudhary, Robert W. Newberry, and Ronald T. Raines (2014). Organic Letters 16, 3421–3423. [PubMed] [PDF] [Supporting Information]
  267. Pyrazine-derived disulfide-reducing agent for chemical biology. John C. Lukesh, III, Kelly K. Wallin, and Ronald T. Raines (2014). Chemical Communications 50, 9591–9594. [PubMed] [PDF] [Supporting Information]
  268. Functional evolution of ribonuclease inhibitor: Insights from birds and reptiles. Jo E. Lomax, Christopher M. Bianchetti, Aram Chang, George N. Phillips, Jr., Brian G. Fox, and Ronald T. Raines (2014). Journal of Molecular Biology 426, 3041–3056. [PubMed] [PDF] [Supporting Information]
  269. Bovine brain ribonuclease is the functional homolog of human ribonuclease 1. Chelcie H. Eller, Jo E. Lomax, and Ronald T. Raines (2014). Journal of Biological Chemistry, 25996–26006. [PubMed][PDF]
  270. Structure of RNA-phosphate cyclase bound to substrate RNA. Kevin K. Desai, Craig A. Bingman, Chin L. Cheng, George N. Phillips, Jr., and Ronald T. Raines (2014). RNA 20, 1560–1566. [PubMed] [PDF] [Supporting Information]
  271. Affinity of monoclonal antibodies for Globo-series glycans. Chelcie H. Eller, Guangbin Yang, Ouathek Ouerfelli, and Ronald T. Raines (2014). Carbohydrate Research 397, 1–6. [PubMed] [PDF] [Supporting Information]
  272. Optimal interstrand bridges for collagen-like biomaterials. I. Caglar Tanrikulu and Ronald T. Raines (2014). Journal of the American Chemical Society 136, 13490–13493.[PubMed] [PDF] [Supporting Information]
  273. Organocatalysts of oxidative protein folding inspired by protein disulfide isomerase. John C. Lukesh, III, Kristen A. Andersen, Kelly K. Wallin, and Ronald T. Raines (2014). Organic & Biomolecular Chemistry 12, 8598–8602. [PubMed] [PDF] [Supporting Information]
  274. Diazo compounds for the bioreversible esterification of proteins. Nicholas A. McGrath, Kristen A. Andersen, Amy K. F. Davis, Jo E. Lomax, and Ronald T. Raines (2015). Chemical Science 6, 752–755. [PubMed] [PDF] [Supporting Information]
  275. ​Intrinsic site-selectivity of ubiquitin dimer formation. Kristen A. Andersen, Langdon J. Martin, Joel M. Prince, and Ronald T. Raines (2015) Protein Science 24, 182–189. [PubMed] [PDF] [Supporting Information]
  276. Catalysis by the tumor-suppressor enzymes PTEN and PTEN-L. Sean B. Johnston and Ronald T. Raines (2015). PLoS ONE 10, e01168098. [PubMed] [PDF]
  277. ​An evolved Mxe GyrA intein for enhanced production of fusion proteins. Carrie J. Marshall, Vanessa A. Grosskopf, Taylor J. Moehling, Benjamin J. Tillotson, Gregory J. Wiepz, Nicholas L. Abbott, Ronald T. Raines, and Eric V. Shusta (2015) ACS Chemical Biology 10, 527–538. [PubMed] [PDF] [Supporting Information]
  278. Conformational stability and catalytic activity of PTEN variants linked to cancers and autism spectrum disorders. Sean B. Johnston and Ronald T. Raines (2015). Biochemistry 54, 55–65. [PubMed] [PDF] [Supporting Information]
  279. Diazo groups endure metabolism and enable chemoselectivity in cellulo. Kristen A. Andersen, Matthew R. Aronoff, Nicholas A. McGrath, and Ronald T. Raines (2015). Journal of the American Chemical Society 137, 2412–2415. [PubMed] [PDF] [Supporting Information]
  280. ​Assignments of RNase A by ADAPT-NMR and Enhancer. Marco Tonelli, Chelcie H. Eller, Kiran K. Singarapu, Woonghee Lee, Arash Bahrami, William M. Westler, Ronald T. Raines, and John L. Markley (2015). Biomolecular NMR Assignments 9, 81–88. [PubMed] [PDF]
  281. 4-Ketoproline: An electrophilic proline analog for bioconjugation. Amit Choudhary, Kimberli J. Kamer, Matthew D. Shoulders, and Ronald T. Raines (2015) Peptide Science 104, 110–115. [PubMed] [PDF] [Supporting Information]
  282. Separation of lignin from corn stover hydrolysate with quantitative recovery of ionic liquid. Kaylee A. Underkofler, Rodrigo E. Teixeira, Stephen A. Pietsch, Kurtis G. Knapp, and Ronald T. Raines (2015) ACS Sustainable Chemistry & Engineering 3, 606–613. [PubMed] [PDF]
  283. Optimized diazo scaffold for protein esterification. Kalie A. Mix and Ronald T. Raines (2015). Organic Letters 17, 2359–2361. [PubMed] [PDF} [Supporting Information]
  284. Thioamides in the collagen triple helix. Robert W. Newberry, Brett VanVeller, and Ronald T. Raines (2015). Chemical Communications 51, 9624–9627. [PubMed] [PDF] [Supporting Information]
  285. Selective inhibition of prolyl 4-hydroxylases by bipyridinedicarboxylates. James D. Vasta and Ronald T. Raines (2105). Bioorganic & Medicinal Chemistry 23, 3081–3090. [PubMed] [PDF] [Suppporting Information]
  286. CartoonFEATURED ARTICLE: Human cancer antigen Globo H is a cell-surface ligand for human ribonuclease 1. Chelcie H. Eller, Tzu-Yuan Chao, Kiran K. Singarapu, Ouathek Ouerfelli, Guangbin Yang, John L. Markley, Samuel J. Danishefsky, and Ronald T. Raines (2015). ACS Central Science 1, 181–190. [PubMed] [PDF] [Supporting Information]
  287. Fluorogenic assay for inhibitors of HIV-1 protease with sub-picomolar affinity. Ian W. Windsor and Ronald T. Raines (2015). Scientific Reports 5, 11286. [PubMed] [PDF]
  288. α/β-Peptide foldamers targeting intracellular protein–protein interactions with activity in living cells. James W. Checco, Erinna F. Lee, Marco Evangelista, Nerida Sleebs, Kelly Rodgers, Anne Pettikiriarachchi, Nadia Kershaw, Geoffrey A. Eddinger, David G. Belair, Julia L. Wilson, Chelcie H. Eller, Ronald T. Raines, William L. Murphy, Brian J. Smith, Samuel H. Gellman, and W. Douglas Fairlie (2015). Journal of the American Chemical Society 137, 11365–11375. [PubMed] [PDF] [Suppporting Information]
  289. Coevolution of RtcB and Archease created a multiple-turnover RNA ligase. Kevin K. Desai, Amanda L. Beltrame, and Ronald T. Raines (2015). RNA 21, 1866–1872. [PubMed] [PDF]
  290. Target selection by natural and redesigned PUF proteins. Douglas F. Porter, Yvonne Y. Koh, Brett VanVeller, Ronald T. Raines, and Marvin Wickens (2015). Proceedings of the National Academy of Sciences, U.S.A. [PubMed] [PDF] [Suppporting Information]
  291. Convenient synthesis of collagen-related peptides for segment condensation. Aubrey J. Ellison, Brett VanVeller, and Ronald T. Raines (2015). Peptide Science 104, 674–681. [PubMed] [PDF] [Suppporting Information]
  292. Crystal structure of N-(3-oxobutanoyl)-L-homoserine lactone. Robert W. Newberry and Ronald T. Raines (2016). Acta Crystallographica E72, 136–139. [PubMed] [PDF]
  293. Selective inhibition of collagen prolyl 4-hydroxylase in human cells. James D. Vasta, Kristen A. Andersen, Kathryn M. Deck, Christopher P. Nizzi, Richard S. Eisenstein, and Ronald T. Raines (2016). ACS Chemical Biology 11, 193–199. [PudMed] [PDF] [Suppporting Information]
  294. Boronate for the traceless delivery of proteins into cells. Kristen A. Andersen, Thomas P. Smith, Jo E. Lomax, and Ronald T. Raines (2016). ACS Chemical Biology 11, 319–323. [PubMed] [PDF] [Suppporting Information]
  295. 1,3-Dipolar cycloadditions of diazo compounds in the presence of azides. Matthew R. Aronoff, Brian Gold, and Ronald T. Raines (2016). Organic Letters 18, 1538–1541. [PubMed] [PDF] [Suppporting Information]
  296. Rapid cycloaddition of a diazo compound with an unstrained dipolarophile. Matthew R. Aronoff, Brian Gold, and Ronald T. Raines (2016). Tetrahedron Letters 57, 2347–2350. [PubMed] [PDF] [Suppporting Information]
  297. Human collagen prolyl 4-hydroxylase is activated by ligands for its iron center. James D. Vasta and Ronald T. Raines (2016). Biochemistry 55, 3224–3233. [PubMed] [PDF] [Suppporting Information]
  298. Replacing a single atom accelerates the folding of a protein and increases its thermostability. Ulrich Arnold and Ronald T. Raines (2016). Organic & Biomolecular Chemistry 14, 6780–6785. [PubMed] [PDF] [Supporting Information]
  299. Decreasing distortion energies without strain: Diazo-selective 1,3-dipolar cycloadditions. Brian Gold, Matthew R. Aronoff, and Ronald T. Raines (2016). Journal of Organic Chemistry 81, 5998–6006. [PubMed] [PDF] [Supporting Information]
  300. nπ* Interactions are competitive with hydrogen bonds. Robert W. Newberry, Samuel J. Orke, and Ronald T. Raines (2016). Organic Letters 18, 3614–3617. [PubMed] [PDF] [Supporting Information]
  301. 1,3-Dipolar cycloaddition with diazo groups: Noncovalent interactions overwhelm strain. Brian Gold, Matthew R. Aronoff, and Ronald T. Raines (2016). Organic Letters 18, 4466–4469. [PubMed] [PDF] [Supporting Information]
  302. Image of CoverCOVER ARTICLE: Peptide tessellation yields micrometre-scale collagen triple helices. I. Caglar Tanrikulu, Audrey Forticaux, Song Jin, and Ronald T. Raines (2016). Nature Chemistry 8, 1008–1014. [PubMed] [PDF] [Supporting Information]
  303. A prevalent intraresidue hydrogen bond stabilizes proteins. Robert W. Newberry and Ronald T. Raines (2016). Nature Chemical Biology 12, 1084–0188. [PubMed] [PDF] [Supporting Information] [Supporting Information]
  304. PTENpred: A designer protein impact predictor for PTEN-related disorders. Sean B. Johnston and Ronald T. Raines (2016). Journal of Computational Biology 23, 969–975. [PubMed] [PDF] [Supporting Information]
  305. Knockout of the ribonuclease inhibitor gene leaves human cells vulnerable to secretory ribonucleases. Sydney P. Thomas, Eunji Kim, Jin-Soo Kim, and Ronald T. Raines (2016). Biochemistry 55, 6359–6362. [PubMed] [PDF] [Supporting Information]
  306. Image of CoverCOVER ARTICLE: Anchoring a cytoactive factor in a wound bed promotes healing. Sayani Chattopadhyay, Kathleen M. Gutherie, Leandro Teixeira, Christopher J. Murphy, Richard R. Dubielzig, Jonathan F. McAnulty, and Ronald T. Raines (2016). Journal of Tissue Engineering and Regenerative Medicine 10, 1012–1020. [PubMed] [PDF]
  307. Prolyl 4-hydroxylase: Substrate isosteres in which an (E)- or (Z)-alkene replaces the prolyl peptide bond. James D. Vasta, Amit Choudhary, Katrina H. Jensen, Nicholas A. McGrath, and Ronald T. Raines (2017). Biochemistry 56, 219–291. [PubMed] [PDF] [Supporting Information]
  308. Molecular basis for the autonomous promotion of cell proliferation by angiogenin. Trish T. Hoang and Ronald T. Raines (2017). Nucleic Acids Research 45, 818–831. [PubMed] [PDF] [Supporting Information]
  309. A boronic acid conjugate of angiogenin that shows ROS-responsive neuroprotective activity. Trish T. Hoang, Thomas P. Smith, and Ronald T. Raines (2017). Angewandte Chemie International Edition, In Press. [PubMed] [PDF] [Supporting Information]

Peer-Reviewed Journal Articles (Education)

  1. An intuitive approach to steady-state kinetics. Ronald T. Raines and David E. Hansen (1988). Journal of Chemical Education 65, 757–759. [PDF]
  2. Binding energy and enzymatic catalysis. David E. Hansen and Ronald T. Raines (1990). Journal of Chemical Education 67, 483–489. [PDF]
  3. Image of CoverCOVER ARTICLE: Analysis of receptor–ligand interactions. Alan D. Attie and Ronald T. Raines (1995). Journal of Chemical Education 72, 119–124. [PDF]

Peer-Reviewed Journal Articles (Reviews)

  1. Ribonuclease A. Ronald T. Raines (1998). Chemical Reviews 98, 1045–1065. [PubMed] [PDF]
  2. Native disulfide bond formation in proteins. Kenneth J. Woycechowsky and Ronald T. Raines (2000). Current Opinion in Chemical Biology 4, 533–539. [PubMed] [PDF]
  3. Cancer chemotherapy--ribonucleases to the rescue. Peter A. Leland and Ronald T. Raines (2001). Chemistry & Biology 8, 405–413. [PubMed] [PDF]
  4. Insights on the conformational stability of collagen. Cara L. Jenkins and Ronald T. Raines (2002). Natural Product Reports 19, 49–59. [PubMed] [PDF]
  5. Catalysis of disulfide bond formation by protein disulfide isomerase and small-molecule mimics. Elizabeth A. Kersteen and Ronald T. Raines (2003). Antioxidants & Redox Signalling 5, 414–424. [PubMed] [PDF]
  6. Chemical synthesis of proteins. Bradley L. Nilsson, Matthew B. Soellner, and Ronald T. Raines (2005). Annual Review of Biophysics and Biomolecular Structure 34, 91–118. [PubMed] [PDF]
  7. Ribonuclease inhibitor: Structure and function. Kimberly A. Dickson, Marcia C. Haigis, and Ronald T. Raines (2005). Progress in Nucleic Acid Research and Molecular Biology 80, 349–374. [PubMed] [PDF]
  8. 2005 Emil Thomas Kaiser award. Ronald T. Raines (2006). Protein Science 15, 1219–1225. [PubMed] [PDF]
  9. Internalization of cationic peptides: The road less (or more?) traveled. Stephen M. Fuchs and Ronald T. Raines (2006). Cellular and Molecular Life Sciences 63, 1819–1822. [PubMed] [PDF]
  10. Symbiosis: Chemical biology at Wisconsin. Laura L. Kiessling, Sally Garbo Wedde, and Ronald T. Raines (2006). ACS Chemical Biology 1, 481–484; 601. [PubMed] [PDF]
  11. Liquid crystal-based analytic technology: Enabling a molecular view of cancer. Paul J. Bertics, Byram H. Ozer, Gregory J. Wiepz, Arturo G. Guadarrama, Nicholas L. Abbott, Aaron M. Lowe, Yiqun Bai, Eric V. Shusta, Nitin Agarwal, Ronald T. Raines, and Jeet Kalia (2007). BIOforum Europe 11, 42–45. [PDF]
  12. Ribonucleases as novel chemotherapeutics: The ranpirnase example. J. Eugene Lee and Ronald T. Raines (2008). BioDrugs 22, 53–58. [PubMed] [PDF]
  13. Bright ideas for chemical biology. Luke D. Lavis and Ronald T. Raines (2008). ACS Chemical Biology 3, 142–155. [PubMed] [PDF] [Poster]
  14. Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity. Thomas J. Rutkoski and Ronald T. Raines (2008). Current Pharmaceutical Biotechnology 9, 185–199. [PubMed] [PDF]
  15. Olefin metathesis for chemical biology. Joseph B. Binder and Ronald T. Raines (2008). Current Opinion in Chemical Biology 12, 767–773. [PubMed] [PDF]
  16. Collagen structure and stability. Matthew D. Shoulders and Ronald T. Raines (2009). Annual Review of Biochemistry 78, 929–958. [PubMed] [PDF]
  17. Advances in bioconjugation. Jeet Kalia and Ronald T. Raines (2010). Current Organic Chemistry 14, 138–147. [PubMed] [PDF]
  18. Prolyl 4-hydroxylase. Kelly L. Gorres and Ronald T. Raines (2010). Critical Reviews in Biochemistry and Molecular Biology 45, 106–124. [PubMed] [PDF]
  19. An evaluation of peptide-bond isosteres. Amit Choudhary and Ronald T. Raines (2011). ChemBioChem 12, 1801–1807. [PubMed] [PDF]
  20. Chemoselectivity in chemical biology: Acyl transfer reactions with sulfur and selenium. Nicholas A. McGrath and Ronald T. Raines (2011). Accounts of Chemical Research 44, 752–761. [PubMed] [PDF]
  21. Bovine pancreatic ribonuclease: Fifty years of the first enzymatic reaction mechanism. Claudi M. Cuchillo, M. Victòria Nogués, and Ronald T. Raines (2011). Biochemistry 50, 7835–7841. [PubMed] [PDF]
  22. Trimethyl lock: A trigger for molecular release in chemistry, biology, and pharmacology. Michael N. Levine and Ronald T. Raines (2012). Chemical Science 3, 2412–2420. [PubMed] [PDF]
  23. Bright building blocks for chemical biology. Luke D. Lavis and Ronald T. Raines (2014). ACS Chemical Biology 9, 855–866. [PubMed] [PDF]
  24. Collagen-based biomaterials for wound healing. Sayani Chattopadhyay and Ronald T. Raines (2014). Biopolymers 101, 821–833. [PubMed] [PDF]
  25. Biomass to furanics: Renewable routes to chemicals and fuels. Benjamin R. Caes, Rodrigo E. Teixeira, Kurtis G. Knapp, and Ronald T. Raines (2015). ACS Sustainable Chemistry & Engineering 3, 2591–2605. [PDF]
  26. Diazo compounds: Versatile tools for chemical biology. Kalie A. Mix, Matthew R. Aronoff, and Ronald T. Raines (2016). ACS Chemical Biology, In Press.
  27. 4-Fluoroprolines: Conformational analysis and effects on the stability and folding of peptides and proteins. Robert W. Newberry and Ronald T. Raines (2017). Topics in Heterocyclic Chemistry. In Press.

Invited Journal Articles

  1. The S-Tag fusion system for protein purification. Ronald T. Raines, Mark McCormick, Thomas R. Van Oosbree, and Robert C. Mierendorf (2000). Methods in Enzymology 326, 362–376. [PubMed] [PDF]
  2. Green fluorescent protein chimeras to probe protein–protein interactions. Sang-Hyun Park and Ronald T. Raines (2000). Methods in Enzymology 328, 251–261. [PubMed] [PDF]
  3. Fast, facile, hypersensitive assays for ribonucleolytic activity. Chiwook Park, Bradley R. Kelemen, Tony A. Klink, Rozamond Y. Sweeney, Mark A. Behlke, Shad R. Eubanks, and Ronald T. Raines (2001). Methods in Enzymology 341, 81–94. [PubMed] [PDF]
  4. Semisynthesis of proteins containing selenocysteine. Robert J. Hondal and Ronald T. Raines (2002). Methods in Enzymology 347, 70–83. [PubMed] [PDF]
  5. Genetic screen to dissect protein–protein interactions: Ribonuclease inhibitor–ribonuclease A as a model system. Sang-Hyun Park and Ronald T. Raines (2002). Methods 28, 346–352. [PubMed] [PDF]
  6. Fluorescence gel retardation assay to detect protein–protein interactions. Sang-Hyun Park and Ronald T. Raines (2004). Methods in Molecular Biology 261, 155–160. [PubMed] [PDF]
  7. Fluorescence polarization assay to quantify protein–protein interactions. Sang-Hyun Park and Ronald T. Raines (2004). Methods in Molecular Biology 261, 161–165. [PubMed] [PDF]
  8. Protein engineering with the traceless Staudinger ligation. Annie Tam and Ronald T. Raines (2009). Methods in Enzymology 462, 25–44. [PubMed] [PDF]
  9. Rational design and evaluation of mammalian ribonuclease cytotoxins. Jo E. Lomax, Chelcie H. Eller, and Ronald T. Raines (2012). Methods in Enzymology 502, 273–290. [PubMed] [PDF]
  10. Creating site-specific isopeptide linkages between proteins with the traceless Staudinger ligation. Kristen A. Andersen and Ronald T. Raines (2015). Methods in Molecular Biology 1248, 55–65. [PubMed] [PDF]
  11. Fluorescence polarization assay to quantify protein–protein interactions–an update. Ronald T. Raines (2015). Methods in Molecular Biology 1278, 323–327. [PubMed] [PDF]
  12. 1-[3-(Diphenylphosphino)-propanoyl]-2,5-pyrrolidindione, First Update. Lindsey R. Orgren and Ronald T. Raines (2017). e-EROS Encyclopedia of Reagents for Organic Synthesis, In Press.

Conference Proceedings

  1. The mechanistic pathway of a mutant triosephosphate isomerase. Ronald T. Raines and Jeremy R. Knowles (1986). In Annals of the New York Academy of Sciences 471: International Symposium on Bioorganic Chemistry (Ronald Breslow, Ed.) pp. 266–272, New York Academy of Sciences, New York. [PubMed] [PDF]
  2. The kinetic consequences of altering the catalytic residues of triosephosphate isomerase. Ronald T. Raines, Donald R. Straus, Walter Gilbert, and Jeremy R. Knowles (1986). In Philosophical Transactions of the Royal Society London A 317: Design, Construction and Properties of Novel Protein Molecules (David M. Blow, Alan R. Fersht, and Greg Winter, Eds.) pp. 371–380, The Royal Society, London. [PDF]
  3. Protein engineering of ribonuclease A. Ronald T. Raines and William J. Rutter (1989). In Structure and Chemistry of Ribonucleases: Proceedings of the First International Meeting (Alexander Pavlovsky and Kostya Polyakov, Eds.), pp. 95–100, Academy of Sciences of the USSR, Moscow. [PDF]
  4. Altering the residues of ribonuclease A. Ronald T. Raines (1991). In Metabolism and Enzymology of Nucleic Acids Including Gene and Protein Engineering: Proceedings of the Seventh International Symposium (Jozef Balan, Ed.), pp. 47–53, Slovak Academy of Sciences, Bratislava. [PDF]
  5. Altering the residues of ribonuclease A. Ronald T. Raines (1991). In Structure, Mechanism and Function of Ribonucleases: Proceedings of the Second International Meeting (Claudi M. Cuchillo, Rafael de Llorens, M. Victòria Nogués, and Xavier Parés, Eds.), pp. 139–143, Universitat Autonòma de Barcelona, Bellaterra, Spain. [PDF]
  6. Ribonuclease A: From model system to cancer chemotherapeutic. Ronald T. Raines (1999). In Enzymatic Mechanisms: Proceedings of the 26th Steenbock Symposium (P. A. Frey and D. B. Northrop, Eds.), pp. 235–249, IOS Press, Washington, DC. [PDF]
  7. The stereoelectronic basis of collagen stability. Ronald T. Raines, Lynn E. Bretscher, Steven K. Holmgren, and Kimberly M. Taylor (2000). In Peptides for the New Millennium: Proceedings of the 16th American Peptide Symposium (Gregg B. Fields, James P. Tam, and Geroge Barany, Eds.), pp. 344–346, Kluwer Academic, Dordrecht, The Netherlands. [PDF]
  8. Contribution of mainchain–mainchain hydrogen bonds to the conformational stability of triple-helical collagen. Mark A. Danielson and Ronald T. Raines (2000). In Peptides for the New Millennium: Proceedings of the 16th American Peptide Symposium (Gregg B. Fields, James P. Tam, and Geroge Barany, Eds.), pp. 347–348, Kluwer Academic, Dordrecht, The Netherlands. [PDF]
  9. Effect of fluoro-substituted proline residues on the conformational stability of triple-helical collagen mimics. Lynn E. Bretscher, Kimberly M. Taylor, and Ronald T. Raines (2000). In Peptides for the New Millennium: Proceedings of the 16th American Peptide Symposium (Gregg B. Fields, James P. Tam, and Geroge Barany, Eds.), pp. 355–356, Kluwer Academic, Dordrecht, The Netherlands. [PDF]
  10. Modulating the conformational stability of triple-helical collagen by chemical modification. Cara L. Jenkins, Kimberly M. Taylor, and Ronald T. Raines (2000). In Peptides for the New Millennium: Proceedings of the Sixteenth American Peptide Symposium (Gregg B. Fields, James P. Tam, and Geroge Barany, Eds.), pp. 357–358, Kluwer Academic, Dordrecht, The Netherlands. [PDF]
  11. Protein assembly using the Staudinger ligation. Bradley L. Nilsson, Matthew B. Soellner, and Ronald T. Raines (2004). In Peptide Revolution: Genomics, Proteomics & Therapeutics: Proceedings of the 18th American Peptide Symposium (Michael Chorev and Tomi K. Sawyer, Eds.), pp. 278–279, Kluwer Academic, Norwell, MA. [PDF]
  12. Effect of 4-fluoroproline in the X-position on the stability of the collagen triple helix. Jonathan A. Hodges and Ronald T. Raines (2004). In Peptide Revolution: Genomics, Proteomics & Therapeutics: Proceedings of the 18th American Peptide Symposium (Michael Chorev and Tomi K. Sawyer, Eds.), pp. 472–473, Kluwer Academic, Norwell, MA. [PDF]
  13. Towards synthetic collagen. Ronald T. Raines (2005). In Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), pp. 181–182, American Chemical Society, New York, NY.
  14. Self-assembly of collagen mimetic peptides. Frank W. Kotch and Ronald T. Raines (2006). In Understanding Biology Using Peptides: Proceedings of the 19th American Peptide Symposium (Sylvie E. Blondelle, Ed.), pp. 688–689, Springer, New York, NY.
  15. Hyperstable collagen based on 4-fluoroproline residues. Ronald T. Raines (2007). In Current Fluoroorganic Chemistry: New Synthetic Directions, Technologies, Materials, and Biological Applications. ACS Symposium Series No. 949 (Vadim Anatol’evich Soloshonok, Koichi Mikami, Takashi Yamazaki, John T. Welch, and John F. Honek, Eds.), pp. 477–486, American Chemical Society, Washington, DC.
  16. Stronger and (now) longer synthetic collagen. Ronald T. Raines (2009). In Peptides for Youth: Proceedings of the 20th American Peptide Symposium (Emanuel Escher, William D. Lubell, and Susan Del Valle, Eds.), pp. xci–xcviii, Kluwer Academic, Norwell, MA. [PubMed] [PDF]
  17. Modulating collagen triple helix stability with 4-chloro-, 4-fluoro-, and 4-methylprolines. Matthew D. Shoulders and Ronald T. Raines (2009). In Peptides for Youth: Proceedings of the 20th American Peptide Symposium (Emanuel Escher, William D. Lubell, and Susan Del Valle, Eds.), pp. 251–252, Kluwer Academic, Norwell, MA. [PubMed] [PDF]
  18. A donor–acceptor perspective on carbonyl–carbonyl interactions in proteins. Amit Choudhary and Ronald T. Raines (2009). In Breaking Away: The Proceedings of the 21stAmerican Peptide Symposium (Michal Lebl, Ed.), pp. 347–349, Prompt Scientific Publishing, San Diego, CA. [PDF]
  19. nπ* Interactions in the molecules of life. Amit Choudhary and Ronald T. Raines (2010). In Peptides 2010: Tales of Peptides. Proceedings of the 31st European Peptide Symposium (Michal Lebl, Morten Meldal, Knud J. Jensen, and Thomas Hoeg-Jensen, Eds.), pp. 2–3, Prompt Scientific Publishing, San Diego, [PDF]
  20. Enzymes as chemotherapeutic agents. Ronald T. Raines (2013). In Chembiomolecular Science: At the Frontier of Chemistry and Biology. Proceedings of the Uehara Memorial Foundation Symposium 2011 (Masakatsu Shibasaki, Masamitsu Iino, and Hiroyuki Osada, Eds.), pp. 281–291, Springer Japan, Tokyo, Japan. [PDF]
  21. nπ* Interactions in helices. Ronald T. Raines (2013). In Peptides Across the Pacific: The Proceedings of the 23rd American Peptide Symposium and the 6th International Peptide Symposium (Michal Lebl, Ed.), pp. 28–29, Prompt Scientific Publishing, San Diego, CA. [PDF]
  22. The main-chain oxygen: Unappreciated effects on peptide and protein structure. Robert W. Newberry and Ronald T. Raines (2015). In Enabling Peptide Research from Basic Science to Drug Discovery: The Proceedings of the 24th American Peptide Symposium (Ved Srivastava, Andrei Yudin, and Michal Lebl, Eds.), pp. 20–21, Prompt Scientific Publishing, San Diego, CA. [PDF]

Book Chapters

  1. Triosephosphate isomerase and proline racemase: Revelation of reaction energetics. Ronald T. Raines (1991). In Enzyme Mechanism from Isotope Effects (Paul F. Cook, Ed.), pp. 431–455, CRC Press, Boca Raton, FL. [PDF]
  2. Altering substrate specificity and detecting processivity in nucleases. Stephen B. del Cardayré, James E. Thompson, and Ronald T. Raines (1994). In Techniques in Protein Chemistry V (John W. Crabb, Ed.), pp. 313–320. Academic Press, New York. [PDF]
  3. One-dimensional diffusion of a protein along a single-stranded nucleic acid. Bradley R. Kelemen and Ronald T. Raines (1997). In Techniques in Protein Chemistry VIII (Daniel R. Marshak, Ed.), pp. 565–572, Academic Press, New York. [PDF]
  4. Protein disulfide isomerase: Cellular enzymology of the CXXC motif. Peter T. Chivers, Martha C. A. Laboissiere, and Ronald T. Raines (1998). In Prolyl Hydroxylase, Protein Disulfide Isomerase, and Other Structurally Related Proteins (Norberto A. Guzman, Ed.), pp. 487–505. Marcel Dekker, New York. [PDF]
  5. Ribonuclease A: From model system to cancer chemotherapeutic. Ronald T. Raines (1999). In Enzymatic Mechanisms (Perry A. Frey and Dexter B. Northrop, Eds.), pp. 235–249, IOS Press, Washington, DC. [PDF]
  6. Monitoring protein–protein interactions with GFP chimeras. Sang-Hyun Park and Ronald T. Raines (2003). In Protein Analysis: A Laboratory Manual (Richard Simpson, Ed.), pp. 766–771, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. [PDF]
  7. Protein assembly to mine the human genome. Bradley L. Nilsson, Matthew B. Soellner, and Ronald T. Raines (2003). In Chemical Probes in Biology, NATO ASI Series (Manfred P. Schneider, Ed.), pp. 359–369, Kluwer Academic Publishers, Dordrecht, The Netherlands. [PDF]
  8. Active site of ribonuclease A. Ronald T. Raines (2004). In Artificial Nucleases (Marina A. Zenkova, Ed.), pp. 19–32, Springer–Verlag, Heidelberg, Germany. [PDF]
  9. Knowles, Jeremy Randall (1935–2008). Ronald T. Raines (2012). In Oxford Dictionary of National Biography (Lawrence Goldman, Ed.), article 99981, Oxford University Press, Oxford, UK. [PDF]

Book Reviews

  1. Book Review. Ribonucleases: Structures and Functions (Giuseppe D'Alessio and James F. Riordan, Eds.). Ronald T. Raines (1998). Protein Science 7, 804–805. [PDF]
  2. Book Review. Biocalorimetry: Applications of Calorimetry in the Biological Sciences (John E. Ladbury and Babur Z. Chowdhry, Eds.) Kimberly M. Taylor and Ronald T. Raines (1999). FEBS Letters 459, 470–471. [PDF]

Commentary

  1. S-Peptide in protein fusion systems: History and significance. Jin-Soo Kim and Ronald T. Raines (1994). inNovations 1, 5–6. [PDF]
  2. Nature's transitory covalent bond. Ronald T. Raines (1997). Nature Structural Biology 4, 424–427. [PubMed] [PDF]
  3. This year's model. Samuel H. Gellman and Ronald T. Raines (2002). Current Opinion in Chemical Biology 6, 727–728. [PDF]
  4. Jeremy R. Knowles (1935–2008). Ronald T. Raines (2008). ACS Chemical Biology 3, 262–264. [PubMed] [PDF]
  5. Peptides and peptidomimetics as prototypes. Helma Wennemers and Ronald T. Raines (2008). Current Opinion in Chemical Biology 12, 690–691. [PubMed] [PDF]
  6. Carpe diubiquitin. Langdon J. Martin and Ronald T. Raines (2010). Angewandte Chemie International Edition 49, 9042–9044. [PubMed] [PDF]

Meeting Abstracts

  1. Triose phosphate isomerase mutants and mechanism–computation vs experiment. Dagmar Ringe, Paul Bash, Martin Karplus, Robert C. Davenport, D. A. Giamonna, Shigetoshi Sugio, Zhidong Zhang, Gregory A. Petsko, Ronald T. Raines, Kathleen D. Liu, Elizabeth A. Komives, Patricia J. Lodi, and Jeremy R. Knowles (1991). FASEB Journal 5(5), Part 2, A1148.
  2. Effect of electron withdrawal on prolyl peptide-bonds. Nicholas Panasik, Eric S. Eberhardt, and Ronald T. Raines (1993). Abstracts of Papers of the American Chemical Society 206, Organic Chemistry, Part 2, 294.
  3. Energies of amide–amide and water–amide hydrogen bonds. Eric S. Eberhardt and Ronald T. Raines (1993). Abstracts of Papers of the American Chemical Society 206, Organic Chemistry, Part 2, 295.
  4. Electronic structure effects on cis/trans peptide bond isomerizations of 4(S)-substituted prolyl derivatives. Michele L. DeRider, Steven J. Wilkens, Zeljko Dzakula, Ronald T. Raines, and John L. Markley (1998). Abstracts of Papers of the American Chemical Society 216, Computational Chemistry, Part 1, 117.
  5. Ribonuclease A: From model system to cancer chemotherapeutic. Ronald T. Raines (2000). Italian Journal of Biochemistry 49(1), 13.
  6. Chemical genetics for the discovery of bioavailable ligands. Joshua J. Higgin, Lisa Friedman, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 221, Medicinal Chemistry, Part 2, 245.
  7. Selenocysteine in native chemical ligation and expressed protein ligation. Robert J. Hondal, Bradley L. Nilsson, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 9. Also as Biochemistry 40(29), 9.
  8. New assay for protein disulfide bond isomerization. Elizabeth A. Kersteen, Seth R. Barrows, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 34. Also as Biochemistry 40(29), 34.
  9. Contribution of individual modules of a leucine-rich repeat protein to its affinity for other proteins. Sunil S. Chandran, Kimberly A. Dickson, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 42. Also as Biochemistry 40(29), 42.
  10. Cytotoxic folate-targeted ribonuclease variants. Bryan D. Smith, Joshua J. Higgin, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 45. Also as Biochemistry 40(29), 45.
  11. Mechanism of ribonuclease cytotoxicity. Kimberly A. Dickson and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 71. Also as Biochemistry 40(29), 71.
  12. Ribonuclease A zymogen as a chemotherapeutic for malaria. Parit Plainkum, Stephen M. Fuchs, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 92. Also as Biochemistry 40(29), 92.
  13. Ribonuclease internalization. Marcia C. Haigis and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 93. Also as Biochemistry 40(29), 93.
  14. Role of lysine residues in the active site of onconase. J. H. Eugene Lee and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 94. Also as Biochemistry 40(29), 94.
  15. Semisynthesis of proteins containing non-natural modules. Ulrich Arnold, Matthew P. Hinderaker, Bradley L. Nilsson, Bayard R. Huck, Samuel H. Gellman, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 97. Also as Biochemistry 40(29), 97.
  16. Semisynthesis of proteins with novel covalent crosslinks. Matthew P. Hinderaker, Ulrich Arnold, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 98. Also as Biochemistry 40(29), 98.
  17. Stereochemical consequences of catalysis by ribonuclease A: Non-natural variants and phosphorothioate substrates. Robert J. Hondal, Richele L. Abel, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 172. Also as Biochemistry 40(29), 172.
  18. Active-site variants of ribonuclease A. Richele L. Abel, Robert J. Hondal, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 181. Also as Biochemistry 40(29), 181.
  19. Effect of guanidinium display on the translocation of molecules through membranes. Stephen M. Fuchs and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 213. Also as Biochemistry 40(29), 215.
  20. Effect of fluoroproline in the X-position on the triple-helical stability of collagen. Jonathan A. Hodges and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 224. Also as Biochemistry 40(29), 226.
  21. Factors affecting the conformational stability of collagen. Cara L. Jenkins, Lynn E. Bretscher, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Biological Chemistry, Part 1, 230. Also as Biochemistry 40(29), 232.
  22. Chemical genetics for the discovery of bioavailable prolyl 4-hydroxylase inhibitors. Joshua J. Higgin, Lisa Friedman, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Medicinal Chemistry, Part 1, 278.
  23. Peptide assembly by the Staudinger ligation. Bradley L. Nilsson, Laura L. Kiessling, and Ronald T. Raines (2001). Abstracts of Papers of the American Chemical Society 222, Organic Chemistry, Part 2, 484.
  24. Semisynthesis of protein variants using intein-mediated protein ligation. Ulrich Arnold, Matthew P. Hinderaker, and Ronald T. Raines (2001). TheScientificWorldJOURNAL 1(S3), 117SR.
  25. Active-site variants of ribonuclease A. Richele L. Abel and Ronald T. Raines (2001). Biophysical Journal 80(1), Part 2, 1144.
  26. A ribonuclease zymogen as a chemotherapeutic for malaria. Parit Plainkum, Stephen M. Fuchs, and Ronald T. Raines (2001). FASEB Journal 15(4), Part 1, A538.
  27. Ribonuclease A: From model system to cancer chemotherapeutic. Ronald T. Raines (2002). Abstracts of Papers of the American Chemical Society 222, Physical Chemistry, Part 2, 124.
  28. Exploring the role of the ribonuclease inhibitor protein in angiogenesis. Kimberly A. Dickson, Peter A. Leland, and Ronald T. Raines (2003). Biochemistry 42(28), 28.
  29. Protein assembly using the Staudinger ligation. Bradley L. Nilsson, Matthew B. Soellner, and Ronald T. Raines (2003). Biopolymers 71(3), P002.
  30. Effect of fluoroproline in the X-position on the stability of the collagen triple helix. Jonathan A. Hodges and Ronald T. Raines (2003). Biopolymers 71(3), P032.
  31. Protein assembly using the Staudinger ligation. Bradley L. Nilsson, Matthew B. Soellner, and Ronald T. Raines (2003). Biopolymers 71(3), P159.
  32. Bioavailable inhibitors of prolyl 4-hydroxylase discovered by chemical genetics. Joshua J. Higgin, Lisa Friedman, and Ronald T. Raines (2003). Abstracts of Papers of the American Chemical Society 225, Medicinal Chemistry, Part 2, 137.
  33. Staudinger ligation: Kinetics and thermodynamics. Matthew B. Soellner, Bradley L. Nilsson, and Ronald T. Raines (2003). Abstracts of Papers of the American Chemical Society 225, Medicinal Chemistry, Part 2, 283.
  34. Comparison of the binding activity of randomly oriented and uniformly oriented proteins immobilized by chemoselective coupling to a self-assembled monolayer. Yan-Yeung Luk, Nicholas L. Abbott, Ronald T. Raines, Matthew L. Tingey, and Kimberly A. Dickson (2003). Abstracts of Papers of the American Chemical Society 226, Biological Chemistry, Part 1, 247. Also as Biochemistry 42(28), 247.
  35. Chemical and biological engineering of enzymes. Ronald T. Raines (2004). Abstracts of Papers of the American Chemical Society 227, Medicinal Chemistry, Part 2, 214.
  36. Hypersensitive probes for in vitro and in vivo fluorescence assays of enzymatic activity. Sunil S. Chandran and Ronald T. Raines (2004). Abstracts of Papers of the American Chemical Society 227, Organic Chemistry, Part 2, 490.
  37. Staudinger ligation: Mechanistic studies and peptide immobilization. Matthew B. Soellner, Bradley L. Nilsson, Kimberly A. Dickson, and Ronald T. Raines (2004). Abstracts of Papers of the American Chemical Society 227, Organic Chemistry, Part 2, 493.
  38. RI evasion is a key factor in BS-RNase cytotoxicity. J. Eugene Lee and Ronald T. Raines (2004). Abstracts of Papers of the American Chemical Society 228, Biological Chemistry, Part 1, 106.
  39. Stereoelectronic effects on protein conformation. Ronald T. Raines (2004). Abstracts of Papers of the American Chemical Society 228, Organic Chemistry, Part 2, 275.
  40. Neuroprotective effect of tris(2-carboxyethyl)phosphine (TCEP) in an optic nerve crush model in the rat. Kyle I. Swanson, Christopher R. Schlieve, Bradley L. Nilsson, Ronald T. Raines, and Leonard A. Levin (2004). Investigative Opthalmology & Visual Science 45, Supplement 1, 849.
  41. Synthesis and characterization of a novel class of thiol reducing agents which are highly neuroprotective for retinal ganglion cells. Christopher R. Schlieve, Bradley L. Nilsson, Ronald T. Raines, and Leonard A. Levin (2005). Investigative Opthamology & Visual Science 46, Supplement S, 188.
  42. Self-assembly of collagen mimetic peptides. Frank W. Kotch and Ronald T. Raines (2005). Biopolymers 80(4), P377.
  43. Chemical and biological engineering of proteins. Ronald T. Raines (2005). Abstracts of Papers of the American Chemical Society 229, Organic Chemistry, Part 2, 1.
  44. Towards synthetic collagen. Ronald T. Raines (2005). Abstracts of Papers of the American Chemical Society 229, Polymer Chemistry, Part 2, 155.
  45. Assembly and fibrillogenesis of collagen mimetic peptides. Frank W. Kotch and Ronald T. Raines (2005). Abstracts of Papers of the American Chemical Society 230, Organic Chemistry, 563.
  46. Impact of charge on the cytotoxicity of human pancreatic ribonucleases. Jeremy R. Johnson, Tzu-Yuan Chao, Luke D. Lavis, Jason G. McCoy, George N. Phillips, Jr., and Ronald T. Raines (2006). Abstracts of Papers of the American Chemical Society 232, Biological Chemistry, 33.
  47. Fluorogenic label for biomolecular imaging. Luke D. Lavis, Tzu-Yuan Chao, and Ronald T. Raines (2006). Abstracts of Papers of the American Chemical Society 232, Biological Chemistry, 117.
  48. Hydroxypyridonate-based Gd(III)-chelates incorporated into ring-opening metathesis polymerization-derived polymers as sensitive imaging agents. Matthew J. Allen, Ronald T. Raines, and Laura L. Kiessling (2006). Abstracts of Papers of the American Chemical Society 232, Inorganic Chemistry, 695.
  49. Novel water-soluble aminophosphinothiol for traceless Staudinger ligation. Annie Tam, Matthew B. Soellner, and Ronald T. Raines (2006). Abstracts of Papers of the American Chemical Society 232, Organic Chemistry, 477.
  50. Human RNase I variants are effective anti-cancer agents. Laura E. Strong, John A. Kink, Mark Shahan, K. Ervin, and Ronald T. Raines (2006). European Journal of Cancer Supplements 4, 125.
  51. Gd(III)-conjugates of ribonuclease A for in vivo transport studies. Matthew J. Allen, Thomas J. Rutkoski, Walter F. Block, Laura L. Kiessling, and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Inorganic Chemistry, 201.
  52. Salicylaldimine ruthenium alkylidene complexes: Metathesis catalysts tuned for protic solvents. Joseph B. Binder, Ilia A. Guzei, and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Inorganic Chemistry, 380.
  53. Polymer-bound Gd(III)-chelates as contrast agents for magnetic resonance imaging. Matthew J. Allen, Walter F. Block, Ronald T. Raines, and Laura L. Kiessling (2007). Abstracts of Papers of the American Chemical Society 233, Inorganic Chemistry, 882.
  54. Net charge is not the primary determinant of onconase cytotoxicity. Rebecca F. Turcotte and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Medicinal Chemistry, 164.
  55. 1,5-Triazoles as cis peptide bond mimics. Annie Tam, Ulrich Arnold, Matthew B. Soellner, and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Organic Chemistry, 52.
  56. Toward synthetic collagen. Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Organic Chemistry, 53–54.
  57. Azido-proteins: Semisynthesis and applications. Jeet Kalia and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Organic Chemistry, 647.
  58. Nanomaterials from self-assembling collagen building blocks. Daniel Gottlieb and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Organic Chemistry, 648.
  59. Synthetic probes for elucidating the mechanism of prolyl 4-hydroxylase. Kelly L. Gorres and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Organic Chemistry, 649.
  60. Contribution of a highly conserved serine residue to ribonuclease activity and stability. R. Jeremy Johnson, Shwan R. Lin, and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Organic Chemistry, 650.
  61. Tuning the pKa of fluorescein: Implications for binding assays. Luke D. Lavis , Thomas J. Rutkoski, and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Organic Chemistry, 651.
  62. Synthesis and characterization of diamino analog of dithiothreitol. Nicole M. McElfresh and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Organic Chemistry, 652.
  63. Effects of hydroxyl-group alkylation on hydroxyproline-containing collagen triple helices. Frank W. Kotch and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Organic Chemistry, 653.
  64. Synthesis of superbly hyperstable collagen triple helices via integration of steric and stereoelectronic effects. Matthew D. Shoulders and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 233, Organic Chemistry, 654.
  65. Intrinsic stability of common linkages used for bioconjugation. Jeet Kalia and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 234, Biological Chemistry, 53.
  66. Chemistry and biology of collagen. Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 234, Biological Chemistry, 112.
  67. Endowing ribonuclease with sequence specificity. Rex Watkins and Ronald T. Raines (2007). Abstracts of Papers of the American Chemical Society 234, Biological Chemistry, 122.
  68. Modulating collagen triple helix stability with 4-chloro, 4-fluoro, and 4-methylprolines. Matthew D. Shoulders and Ronald T. Raines (2007). Biopolymers 88(4), 593.
  69. Toxicology of a potent human RNase variant. Laura E. Strong, John A. Kink, Mark N. Shahan, Beigen Mei, Kerry M. Ervin, and Ronald T. Raines (2007). Molecular Cancer Therapeutics 6, 3359S–3360S.
  70. Design of Phase 1 trial of a human ribonuclease variant. Laura Strong, John A. Kink, Mark N. Shahan, Baigen Mei, and Ronald T. Raines (2008). Journal of Clinical Oncology 26 (May 20 Supplement), 14646.
  71. Latent fluorophores for biomolecular imaging. Ronald T. Raines (2008). FASEB Journal 22, 117.3.
  72. Substrate specificity and conformational preferences of prolyl 4-hydroxylase. Kelly L. Gorres and Ronald T. Raines (2008). FASEB Journal 22, 609.1.
  73. Antagonists of ribonuclease inhibior: Small molecules, dendrimers, and peptides. Gregory A. Ellis, Luke D. Lavis, R. Jeremy Johnson, and Ronald T. Raines (2008). FASEB Journal 22, 651.1.
  74. Prenylation dependant localization of peptides and proteins in vivo. James W. Wollack, Nicholette A. Zeliadt, Margie T. Borra, Jinhwa A. Chung, Daniel G. Mullen, Stephen M. Fuchs, Ronald T. Raines, T. Andrew Taton, Elizabeth V. Wattenberg, Mark D. Distefano (2008). Abstracts of Papers of the American Chemical Society 236, Biological Chemistry, 85.
  75. Fluorinated collagen as a biomaterial and in nanotechnology. Ronald T. Raines (2008). Abstracts of Papers of the American Chemical Society 236, Fluorine Chemistry, 18.
  76. Forces that stabilize the collagen triple helix. Matthew D. Shoulders and Ronald T. Raines (2008). Abstracts of Papers of the American Chemical Society 236, Medicinal Chemistry, 6.
  77. QBI-139, a human RNase variant in a Phase I trial, has broad in vivo efficacy. Laura E. Strong, John A. Kink, Baigen Mei, Mark N. Shahan, Dan Pensinger, and Ronald T. Raines (2009). Molecular Cancer Therapeutics 8(12), Supplement 1, C42.
  78. Simple chemical transformation of lignocellulosic biomass into fuels and chemicals. Joseph B. Binder and Ronald T. Raines (2009). Abstracts of Papers of the American Chemical Society 237, Carbohydrates, 61.
  79. Production of 5-hydroxymethylfurfural from carbohydrates in switchable solvent systems. Benjamin R. Caes, Joseph B. Binder, and Ronald T. Raines (2009). Abstracts of Papers of the American Chemical Society 237, Organic Chemistry, 539.
  80. Determinants of collagen triple-helix stability in the Xaa position. Matthew D. Shoulders, Frank W. Kotch, and Ronald T. Raines (2009). Abstracts of Papers of the American Chemical Society 238, Organic Chemistry, 451.
  81. QBI-139, a human RNase variant in a Phase I trial, works in combination. Laura E. Strong, John A. Kink, Baigen Mei, Mark N. Shahan, and Ronald T. Raines (2010). Proceedings of the 101st Annual Meeting of the American Association for Cancer Research, 5390.
  82. Relationship of QBI-139, a human ribonuclease variant, and RNA in cancer cells. Laura E. Strong, John A. Kink, Baigen Mei, Mark N. Shahan, D. Pensinger, and Ronald T. Raines (2010). Journal of Clinical Oncology 28 (Supplement), e13650.
  83. Use of a human ribonuclease variant, QBI-139, for the treatment of cancer. Laura E. Strong, John A. Kink, Baigen Mei, Mark N. Shahan, and Ronald T. Raines (2010). Journal of Clinical Oncology 28:15s (Supplement), TPS162.
  84. Ribonuclease: From model system to the clinic. Ronald T. Raines (2010). Abstracts of Papers of the American Chemical Society 240, Biological Chemistry, 133.
  85. Fermentable sugars by chemical hydrolysis of biomass in an ionic liquid. Ronald T. Raines (2010). Abstracts of Papers of the American Chemical Society 240, Fuel Chemistry, 64.
  86. Combinations of QBI-139, a clinical stage ribonuclease drug. Laura E. Strong, John A. Kink, Daniel Pensinger, Baigen Mei, Mark N. Shahan, and Ronald T. Raines (2011). Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research, 2573.
  87. A Phase I clinical trial of QBI-130, a human ribonuclease variant, in solid tumors. Laura E. Strong, John A. Kink, Baigen Mei, Mark N. Shahan, and Ronald T. Raines (2011). Journal of Clinical Oncology 29 (Supplement), TPS146.
  88. Chemical transformation of lignocellulosic biomass into furanics and sugars. Ronald T. Raines (2011). Abstracts of Papers of the American Chemical Society 241, Cellulose and Renewable Materials Chemistry, 261.
  89. Electronic effects on protein structure. Ronald T. Raines (2011). Abstracts of Papers of the American Chemical Society 241, Organic Chemistry, 376.
  90. Collagen mimetic peptides enable cutaneous wound assessment and expedite healing. Sayani Chattopadhyay, Kathy M. Guthrie, Leandro Teixeira, Lingyin Li, Laura L. Kiessling, Richard R. Dubeizig, Christopher J. Murphy, Jonathan F. McAnulty, and Ronald T. Raines (2011). Biopolymers 96(4), 427.
  91. Efficacy of ribonuclease QBI-139 in combination with standard of care therapies. Laura E. Strong, John A. Kink, Daniel Pensinger, Baigen Mei, Mark Shahan, and Ronald T. Raines (2012). Cancer Research 72(8), Supplement 1, 1838.
  92. First-in-human phase I clinical trial of QBI-139, a human ribonuclease variant, in solid tumors. Laura E. Strong, John A. Kink, Baigen Mei, Mark N. Shahan, and Ronald T. Raines (2012). Journal of Clinical Oncology 30 (Supplement), TPS3113.
  93. Organocatalytic conversion of cellulose to furans for fuels and chemicals. Benjamin R. Caes, Michael J. Palte, and Ronald T. Raines (2012). Abstracts of Papers of the American Chemical Society 243, Cellulose, 70.
  94. Interaction of nucleic acids with the glycocalyx. Michael J. Palte and Ronald T. Raines (2012). Abstracts of Papers of the American Chemical Society 243, Medicinal Chemistry, 439.
  95. Electronic effects on protein structure. Ronald T. Raines (2012). Abstracts of Papers of the American Chemical Society 243, Organic Chemistry, 1.
  96. Development of a yeast surface display platform for site-specific protein modifications. Carrie Marshall, Nitin Agarwal, Jeet Kalia, Nicholas A. McGrath, Ronald T. Raines, and Eric V. Shusta (2013). Abstracts of Papers of the American Chemical Society 245, Biotechnology, 417.
  97. Electronic effects within the protein backbone. Ronald T. Raines (2012). Abstracts of Papers of the American Chemical Society 244, Organic Chemistry, 66.
  98. Modulation of collagen stability with fluoro groups. Ronald T. Raines (2013). Abstracts of Papers of the American Chemical Society 245, Fluorine Chemistry, 24.
  99. nπ* Interactions in proteins and small molecules. Ronald T. Raines (2013). Abstracts of Papers of the American Chemical Society 245, Medicinal Chemistry, 6.
  100. Diazo compounds as highly tunable 1,3-dipoles for cycloaddition reactions with cyclooctynes. Nicholas A. McGrath and Ronald T. Raines (2013). Abstracts of Papers of the American Chemical Society 245, Organic Chemistry, 221.
  101. Construction of a potent, versatile disulfide-reducing agent from aspartic acid. John C. Lukesh, Michael J. Palte, and Ronald T. Raines (2013). Abstracts of Papers of the American Chemical Society 245, Organic Chemistry, 222.
  102. Longer, stronger synthetic collagens for nanotechnology and biomedicine. Ronald T. Raines (2013). Abstracts of Papers of the American Chemical Society 245, Organic Chemistry, 763
  103. RNases: Approaching RNA as a target for cancer therapy. Laura E. Strong, John Kink, Baigen Mei, Mark Shahan and Ronald T. Raines (2013). Cancer Research 73(8), Supplement 1, 4405.
  104. nπ* Interactions in peptides and proteins. Ronald T. Raines (2013). Biopolymers 100(3), 232.
  105. Protection and detection of boronic acids. Matthew Aronoff, Brett VanVeller, and Ronald T. Raines (2014). Abstracts of Papers of the American Chemical Society 247, Organic Chemistry 662.
  106. Selective and bioavailable inhibitors of collagen prolyl 4-hydroxylase. James D. Vasta, Kristen A. Andersen, and Ronald T. Raines (2014). Abstracts of Papers of the American Chemical Society 248, Biological Chemistry 182.
  107. Convergent semisynthetic route to authentic ubiquitin chains. Kristen A. Andersen and Ronald T. Raines (2014). Abstracts of Papers of the American Chemical Society 248, Biological Chemistry 203.
  108. Bovine brain ribonuclease is the functional homolog of human ribonuclease 1. Chelcie H. Eller, Jo E. Lomax, and Ronald T. Raines (2014). Protein Science 23, Supplement 1, 102–103.
  109. nπ* Interactions in protein structure and folding. Robert W. Newberry and Ronald T. Raines (2014). Protein Science 23, Supplement 1, 238.