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Published Data Sets for Download

Meyer MB, Lee SM, Carlson AH, Benkusky NA, Kaufmann M, Jones G, Pike JW. A chromatin-based mechanism controls differential regulation of the cytochrome P450 gene Cyp24a1 in renal and non-renal tissues. J Biol Chem. 2019 Aug 22. pii: jbc.RA119.010173. doi: 10.1074/jbc.RA119.010173. [PubMed]

Meyer MB, Benkusky NA, Kaufmann M, Lee SM, Redfield RR, Jones G, Pike JW. Employing targeted genomic deletions to identify enhancer function and generate a kidney-specific, endocrine-deficient Cyp27b1 pseudo-null mouse. J Biol Chem. 2019 Jun 14;294(24):9518-9535. [PubMed]

Meyer MB, Benkusky NA, Kaufmann M, Lee SM, Onal M, Jones G, Pike JW. A kidney-specific genetic control module in mice governs endrocrine regulation of the cytochrome P450 gene Cyp27b1 essential for vitamin D3 activation. 2017 June 14. pii: jbc.M117.806901. doi: 10.1074/jbc.M117.806901. [PubMed]

Meyer MB, Benkusky NA, Sen B, Rubin J, Pike JW. Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-Derived Mesenchymal Stem Cells. J Biol Chem. 2016 July 11  doi:10.1074/jbc.M116.736538 [JBC early release] [PubMed]

  • GEO Data Accession Link -> GSE79815
  • To display the ChIP-seq overlaid data track HUBs in the UCSC genome browser:
    • Go to UCSC Genome Browser (mm9)
    • Search Public Hubs for GSE79815 (near the bottom of the list)
    • Click "connect", then on the next screen enter your genomic region of interest and hit "Go"

Lee SM, Riley EM, Meyer MB, Benkusky NA, Plum LA, DeLuca HF, Pike JW. 1,25-Dihydroxyvitamin D3 Controls a Cohort of Vitamin D Receptor Target Genes in the Proximal Intestine that is Enriched for Calcium Regulating Components. J Biol Chem 2015 Jun 3 doi: jbc.M115.665794. [PubMed]

Meyer MB, Benkusky NA, Pike JW.  Selective Distal Enhancer Control of the Mmp13 Gene Identified through CRISPR Genomic Deletions. J Biol Chem. 2015 Apr 24;290(17):11093-107. [PubMed]

St John HC, Meyer MB, Benkusky NA, Carlson AH, Prideaux M, Bonewald LF, Pike JW. The parathyroid hormone-regulated transcriptome in osteocytes: Parallel actions with 1,25-dihydroxyvitamin D3 to oppose gene expression changes during differentiation and to promote mature cell function. Bone 2014 Nov 22;72C:81-91. [PubMed]

St John HC, Bishop KA, Meyer MB, Benkusky NA, Pike JW. The osteoblast to osteocyte transition: epigenetic changes and response to the vitamin D3 hormone. Mol Endocrinol 2014 Jul;28(7):1150-65. [PubMed]

Meyer MB, Benkusky NA, Lee CH, Pike JW.  Genomic Determinants of Gene Regulation by 1,25-Dihydroxyvitamin D3 During Osteoblast-Lineage Cell Differentiation.  J Biol Chem. 2014 Jul 11;289(28):19539-54. [PubMed]

Meyer MB, Benkusky NA, Pike JW. The RUNX2 Cistrome in Osteoblasts: Characterization, Downregulation Following Differentiation and Relationship to Gene Expression. JBC. 2014 Jun 6;289(23):16016-31. [PubMed]

Meyer MB, Pike JW. Corepressors (NCoR and SMRT) as well as Coactivators are Recruited to PositivelyRegulated 1α,25-Dihydroxyvitamin D3-Responsive Genes. J Steroid Biochem Mol Biol. 2012 Aug 25. doi:pii: S0960-0760(12)00149-5. 10.1016/j.jsbmb.2012.08.006. [ PubMed]

Meyer MB, Goetsch PD, Pike JW. VDR/RXR and TCF4/β-Catenin Cistromes in Colonic Cells of ColorectalTumor Origin: Impact on c-FOS and c-MYC Gene Expression. Mol Endocrinol. 2012 Jan;26(1):37-51. [PubMed]