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Information for Prospective Post-doctoral Scholars


Lab Profile
Our laboratory has a nice mix of Assistant Scientists, post-doctoral scholars, graduate students, technicians, and undergraduate students. Some of the projects are team efforts while others are being pursued by individuals. We enjoy having scholars from diverse scientific backgrounds.


The laboratory uses the most current methods in mouse genetics to map and positionally clone genes relevant to obesity and diabetes. Recent technological advances have greatly accelerated the pace of discovery.

Our group was among the first to apply microarray technology to the study of obesity and diabetes. We have advanced far beyond the original applications to now merge this technology with genetics and metabolomics.

We have a very strong collaboration with two prominent statisticians, Brian Yandell and Christina Kendziorski. They are developing new approaches to the analysis of genetic and genomic data. Examples of their research include: better methods for determining differential gene expression, the development of networks from the correlation structures of gene expression, and ways to study epistasis.

Physiology and biochemistry
Our mantra is that genetics is only as good as the phenotype. For much of our genetics work, the genetics approaches are mere tools and the creative and intellectually challenging components are the physiological and biochemical phenotypes. Thus, we welcome scholars with a strong background in biochemistry and physiology; we can teach anyone genetics.

Teaching opportunities
Many post-doctoral scholars wish to pursue university careers that include teaching. Many also have a special passion for teaching. Alan Attie has an interest in educational reform and has worked with many post-docs and graduate students to develop alternatives to classic monologue-based teaching. Alan sees the classroom as a laboratory where one can do creative experimentation.
Post-docs may gain teaching experience by assisting in teaching of existing courses or by developing new experimental courses in cooperation with other trainees and under Alan's supervision and guidance.

Supervision of undergraduate students
Our Department has a large pool of talented undergraduate majors who seek laboratory research opportunities. Post-docs who wish to gain experience as research mentors can recruit excellent students from this pool.

Future Employment opportunities
Past post-docs are now employed in research universities running labs and teaching, at undergraduate colleges teaching, and in pharmaceutical and biotechnology companies. Presently, there is a big demand for people with combined skills in genetics and physiology and with a research interest in metabolic diseases. Because of the worldwide obesity and diabetes epidemic, there is presently a shortage of researchers with expertise in these areas, both in academia and in industry.

To apply for a post-doctoral position
We welcome applications from scholars interested in pursuing research in diabetes. We have projects in genetics, genomics, and physiology/biochemistry of insulin resistance and (-cell proliferation and function.

Applicants should have a strong research background in biochemistry, physiology and/or in genetics/genomics. Scholars with a strong interest and background in metabolism would fit very well into our laboratory. Please send a CV, a cover letter, and the names of at least three references (with email and telephone numbers) to Alan Attie (Email: