James M. Ntambi

Photo of James M. Ntambi
Katherine Berns Von Donk Steenbock Professor (also Nutritional Sciences)
BSc. and MSc., Makerere University, Kampala, Uganda
Ph.D., Johns Hopkins University School of Medicine, Baltimore, MD
Phone: (608) 265-3700
Email: ntambi@biochem.wisc.edu

Publications

191. ALJohani AM, Syed DN, Ntambi JM. (2017 Insights into Stearoyl-CoA Desaturase-1 Regulation of Systemic Metabolism. Trends Endocrinol Metab. (Epub) PMID: 29089222 [PubMed]

190. Forney LA, Stone KP, Wanders D, Ntambi JM, Gettys TW. (2017) The role of suppression of hepatic SCD1 expression in the metabolic effects of dietary methionine restriction. Appl Physiol Nutr Metab. (Epub) PMID: 28982014 [PubMed]

189. Lounis MA, Bergeron KF, Burhans MS, Ntambi JM, Mounier C. (2017) Oleate increases SREBP-1 signaling activity in SCD1 deficient hepatocytes. Am J Physiol Endocrinol Metab. (Epub) PMID: 28851735 [PubMed]

188. Christoph MJ, Grigsby-Toussaint DS, Baingana R, Ntambi JM. (2017) Physical Activity, Sleep, and BMI Percentile in Rural and Urban Ugandan Youth. Ann of Glob Health 83 (2) 311-319. PMID: 28619406 [PubMed]

187. Ansari IH, Longacre MJ, Stoker SW, Kendrick MA, O'Neill LM, Zitur LJ, Fernandez LA, Ntambi JM, MacDonald MJ. (2017) Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion. Arch Biochem Biophys. 618:32-43. PMID: 28193492 [PubMed]

186. Miller KN, Burhans MS, Clark JP, Howell PR, Polewski MA, DeMuth TM, Eliceiri KW, Lindstrom MJ, Ntambi JM, Anderson RM. (2017) Aging and caloric restriction impact adipose tissue, adiponectin, and circulating lipids. Aging Cell. Feb 03. doi: 10.1111/acel.12575. PMID: 28156058 PMCID: PMC5418198 [PubMed]

185. Lai KKY, Kweon SM, Chi F, Hwang E, Kabe Y, Higashiyama R, Qin L, Yan R, Wu RP, Lai K, Fujii N, French S, Xu J, Wang JY, Murali R, Mishra L, Lee JS, Ntambi JM, Tsukamoto H. (2017) Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via Wnt Signaling and Stabilization of Low Density Lipoprotein Receptor-related Proteins 5 and 6.  Gastroenterology. 152(6):1477-1491. PMID: 28143772 [PubMed]

184. Bednarski T, Olichwier A, Opasinska A, Pyrkowska A, Gan AM, Ntambi JM, Dobrzyn P. (2016) Stearoyl-CoA desaturase 1 deficiency reduces lipid accumulation in the heart by activating lipolysis independently of peroxisome proliferator-activated receptor alpha. Biochim Biophys Acta 1861 (12), 2029-2037. PMID: 27751891 [PubMed]

183. Sawin EA, Stroup BM, Murali SG, O'Neill LM, Ntambi JM, Ney DM. (2016) Differential Effects of Dietary Fat Content and Protein Source on Bone Phenotype and Fatty Acid Oxidation in Female C57Bl/6 Mice. PLoS One Oct 03. PMID: 27695036 PMCID: PMC5047596 [PubMed]

182. Lounis MA, Escoula Q, Veillette C, Bergeron KF, Ntambi JM, Mounier C. (2016) SCD1 deficiency protects mice against ethanol-induced liver injury. Biochim Biophys Acta. 1861(11) 1662-1670. PMID: 27477676 [EPublish PubMed]

181. Xueqing Liu, Maggie S. Burhans, Matthew T. Flowers, James M. Ntambi (2016) Hepatic oleate regulates liver stress response partially through PGC-1α during high-carbohydrate feeding. J Hepatology 65, 103-112. PMID:26976120. PMCID: PMC4939798 [PubMed]

180. James M. Ntambi (2016) miRNAs Caught Up in Metabolic Organ Crosstalk to Combat Obesity. EBioMedicine  5, 10-11. PMID: 27077099 PMCID: PMC4816838 [PubMed]

179. Guo, C-A, Bond LM, and Ntambi JM. Metabolic Regulation of Inflammation. (2016) In: Frontiers in Inflammation
Vol. 1, 83-105.

178. Maggie S. Burhans and James M. Ntambi (2016) Monounsaturated Fatty Acid Mediated Liver-Adipose Tissue Crosstalk and Metabolic Regulation. In: Hepatic De Novo Lipogenesis and Regulation of Metabolism J. M. Ntambi Editor Springer. pages 255-266.

177. Mohamed Amine, Lounis Sabri Rial, James M. Ntambi Catherine Mounier (2016) Role of Lipogenesis and Lipid Desaturases in Non-alcoholic Fatty Liver Disease. In: Hepatic De Novo Lipogenesis and Regulation of Metabolism J. M. Ntambi Editor Springer. pages 189-210.

176. Vishal Singh, Beng San Yeoh, James M. Ntambi, Matam Vijay-Kumar (2016) Influence of Gut Microbiota on Hepatic Lipogenesis and Disease Pathogenesis. In: Hepatic De Novo Lipogenesis and Regulation of Metabolism J. M. Ntambi Editor Springer. pages 143-164.

175. James M. Ntambi Editor (2016) Hepatic De Novo Lipogenesis and Regulation of Metabolism. Springer.

174. Masuda M, Miyazaki-Anzai S, Keenan AL, Okamura K, Kendrick J, Chonchol M, Offermanns S, Ntambi JM, Kuro-O M, Miyazaki M (2015) Saturated phosphatidic acids mediate saturated fatty acid-induced vascular calcification and lipotoxicity. J Clin Invest. 125(12):4544-4558. PMID: 26517697 [PubMed]

173. Vishal Singh, Benoit Chassaing, Limin Zhang, Beng San Yeoh, Xia Xiao Manish Kumar, Mark T Baker, Kevin Harvatine, James M Ntambi, Andrew D. Patterson, Andrew Gewirtz, Matam Vijay-Kumar (2015) Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase (SCD-1) Determines Metabolic Syndrome in TLR5-Deficient Mice. Cell Metabolism 22(6):983-96. PMID: 26525535 [PubMed]

172. Laura M. Bond, Makoto Miyazaki, Lucas M. O’Neill, Fang Ding, James M. Ntambi (2015) Fatty Acid Desaturation and Elongation in Mammals. In: Biochemistry of Lipids, Lipoproteins and Membranes. 6th edition D. E. Vance and J. E. Vance Editors

171. Polewski MA, Burhans MS, Zhao M, Colman RJ, Shanmuganayagam D, Lindstrom MJ, Ntambi JM, Anderson RM (2015) Plasma diacylglycerol composition is a biomarker of metabolic syndrome onset in rhesus monkeys. J. Lipid Res. 2015, 56: 1461-1470. PMID: 26063458 [PubMed]

170. Marty AJ, Broman AT, Zarnowski R, Dwyer TG, Bond LM, Lounes-Hadj Sahraoui A, Fontaine J, Ntambi JM, Keleş S, Kendziorski C, Gauthier GM. (2015) Fungal morphology, iron homeostasis, and lipid metabolism regulated by a GATA transcription factor in Blastomyces dermatitidis. PLoS Pathog 11(6): e1004959. doi:10.1371/journal.ppat.1004959.   PMID: 26114571 [PubMed]

169. MacDonald MJ, Ade L, Ntambi JM, Stoker SW. (2015) Characterization of Phospholipids in Insulin Secretory Granules and Mitochondria in Pancreatic Beta Cells and Their Changes with Glucose Stimulation. J Biol Chem. 290 11075-11092. PMID: 25762724 [PubMed]

168. Burhans MS, Flowers MT, Harrington KR, Bond LM, Guo CA, Anderson RM, Ntambi JM (2015) Hepatic oleate regulates adipose tissue lipogenesis and fatty acid oxidation. J. Lipid Res. 56:(2) 304-318.  PMID: 25555387 [PubMed]

167. Ntambi JM (2014) Stearoyl-CoA desaturases are regulators of lipid metabolism in skin. Chapter 15, “Lipids and Skin Health” Pappas Editor Springer.

166. Chang-An Guo, Lucas M O’Neill, and 
 James M Ntambi (2014) Gene Inactivation Strategies: An Update. In: eLS. John Wiley & Sons, Ltd: Chichester. [Wiley] [doi: 10.1002/9780470015902.a0021020.pub2]

165. Mandrup S, MacDougald OA, Moss J, Ntambi J, Pekala P, Tang QQ, Wolfgang M, Bernlohr DA. (2014) In memoriam: M. Daniel Lane, 1930-2014. Trends Endocrinol Metab. S1043-2760(14)00124-6. [PubMed]

164. Zarnowski R, Westler WM, Lacmbouh GA, Marita JM, Bothe JR, Bernhardt J, Lounes-Hadj Sahraoui A, Fontaine J, Sanchez H, Hatfield RD, Ntambi JM, Nett JE, Mitchell AP, Andes DR (2014) Novel entries in a fungal biofilm matrix encyclopedia. mBio 5(4):e01333-14. PMID: 25096878 [PubMed]

163. Elizabeth A. Berkley, Scott D. Peckham, Harini Sampath, Joseph Bodewes, James M. Ntambi and Tomothy R. Deelen (2014) Ingestion of Fat Tissue From Wolf Prey Species and Its Influence on Fatty-Acid Composition in Sled Dogs. Wildlife Society Bulletin 38(1):51–59. [WileyOnline]

162. Nicholas J Friedlander; Maggie S Burhans, Ph.D.; Lacmbouh Ade; Lucas M O'Neill; Xiaoli Chen, M.D., Ph.D. James M Ntambi PhD (2014) Global deletion of lipocalin 2 does not reverse high-fat diet-induced obesity resistance in stearoyl-CoA desaturase-1 skin-specific knockout mice. BBRC 445(3):578-583. PMID: 24548407 [PubMed]

161. Harini Sampath and James M. Ntambi. (2014) Role of Stearoyl-CoA Desaturase-1 in Skin Integrity and Whole Body Energy Balance. J. Biol. Chem. 289: 2482-2488. PMID: 24356954 [PubMed]

160. James M. Ntambi. (2013) Stearoyl-CoA Desaturase-1 is a regulator of Energy Homeostasis. In: Stearoyl-CoA Desaturase Genes in Lipid Metabolism. J. M. Ntambi Editor Springer pp. 27-35.

159. Jie Liu, Resat Cinar, Keming Xiong, Grzegorz Godlewski, Tony Jourdan, Yuhong Lin, James M. Ntambi, and George Kunos (2013) Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase. PNAS 110 (47) 18832-18837. PMID: 24191036 [PubMed]

158. Michael P. Rogowski, Matthew T. Flowers, Alexis D. Stamatikos, James M. Ntambi, and Chad M. Paton (2013) SCD1 activity in muscle increases triglyceride PUFA content, exercise capacity, and PPARδ expression in mice. J. Lipid Res. Oct;54(10):2636-46. PMID: 23918045 [PubMed]

157. Laura Bond and James M. Ntambi (2013) Stearoyl-CoA Desaturase Genes 3 and 4: Avenues for Tissue Specific D9 Desaturase Activity. In: Stearoyl-CoA Desaturase Genes In Lipid Metabolism. J. M. Ntambi Editor Springer pp 131.

156. Jennifer L. Cantley, Lucas M. O’Neil, James M. Ntambi and Michael P. Czech (2013) The Cellular Function of Stearoyl-CoA Desaturase-2 in Development and Differentiation. In: Stearoyl-CoA desaturase Genes in Lipid Metabolism. J. M. Ntambi Editor Springer pp 119.

155. James M. Ntambi (2013) Stearoyl-CoA Desaturase-1 is a regulator of Energy Homeostasis. In: Stearoyl-CoA Desaturase Genes in Lipid Metabolism. J. M. Ntambi Editor Springer pp 27.

154. Macdonald MJ, Hasan NM, Dobrzyn A, Stoker SW, Ntambi JM, Liu X, Sampath H. (2013) Knockdown of pyruvate carboxylase or fatty acid synthase lowers numerous lipids and glucose-stimulated insulin release in insulinoma cells. Arch Biochem Biophys. 532(1): 23-31. PMID: 23357280 [PubMed]

153. Anna Dziewulska, Pawel Dobrzyn, Magdalena Jazurek, Aleksandra Pyrkowska, James M. Ntambi and Agnieszka Dobrzyn (2012) Monounsaturated fatty acids are required for membrane translocation of protein kinase C-theta induced by lipid overload in skeletal muscle Mol. Mem. Biol 29(7): 309–320. PMID: 22881371 [PubMed]

152. Lisa Krugner-Higby, Richard Brown, Matthew Rassette, Melissa Behr, Ogi Okwumabua, Mark Cook, Cynthia Bell, Matthew T Flowers, James M. Ntambi and Annette Gendron (2012) Ulcerative Dermatitis in C57BL/6 Mice Lacking Stearoyl CoA Desaturase. Comp Med 2012. 62: 257-263. [CompMed]

151. Flowers MT, Ade L, Strable MS, Ntambi JM (2012) Combined deletion of SCD1 from adipose tissue and liver does not protect mice from obesity. J Lipid Res. Aug;53(8):1646-53. Epub 2012 Jun 5. PMID: 22669918 [PubMed]

150. Scott KE, Wheeler FB, Davis AL, Thomas MJ, Ntambi JM, Seals DF, Kridel SJ (2012) Metabolic regulation of invadopodia and invasion by acetyl-CoA carboxylase 1 and de novo lipogenesis. PLoS One.;7(1):e29761. PMID: 22238651 [PubMed]

149. Sampath H and Ntambi JM (2011) The role of stearoyl-CoA desaturase in obesity, insulin resistance, and inflammation. Ann N Y Acad Sci. Dec;1243:47-53. doi: 10.1111/j.1749-6632.2011.06303.x. Review.PMID: 22211892 [PubMed]

148. Kim E, Lee JH, Ntambi JM, Hyun CK (2011) Inhibition of stearoyl-CoA desaturase1 activates AMPK and exhibits beneficial lipid metabolic effects in vitro. Eur J Pharmacol. Dec 15;672(1-3):38-44. PMID: 21970804[PubMed]

147. Deckelbaum RJ, Ntambi JM, Wolgemuth DJ (2011)  Basic science research and education: a priority for training and capacity building in developing countries. Infect Dis Clin North Am. Sep;25(3):669-676. PMID: 21896366 [PubMed]

146. James M. Ntambi (2011) Obesity in Africa highlights this global epidemic ASBMB today 36.

145. Flowers MT, Paton CM, O'Byrne SM, Schiesser K, Dawson JA, Blaner WS, Kendziorski C, Ntambi JM. (2011) Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism. PLoS One. May 9;6(5):e19734. PMID: 21573029 [PubMed]

144. Sampath H, Ntambi JM. (2011) The role of fatty acid desaturases in epidermal metabolism. Dermatoendocrinol. Apr;3(2):62-4. PMID: 21695013 [PubMed]

143. Xueqing Liu, Maggie S. Strable, and James M. Ntambi (2011) Stearoyl CoA desaturase 1: role in cellular inflammation and stress. Adv Nutr. Jan;2(1):15-22. doi: 10.3945/an.110.000125. Review. PMID: 22211186 [PubMed]

142. Liu S, Hatano B, Zhao M, Yen CC, Kang K, Reilly SM, Gangl MR, Gorgun C, Balschi JA, Ntambi JM, Lee CH. (2011) Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation. J Biol Chem. Jan 14;286(2):1237-47. PMID: 21059653 [PubMed]

141. Paton CM, Ntambi JM. (2010) Loss of stearoyl-CoA desaturase activity leads to free cholesterol synthesis through increased Xbp-1 splicing. Am J Physiol Endocrinol Metab. Dec;299(6):E1066-75. PMID: 20923962 [PubMed]

140. Hyun CK, Kim ED, Flowers MT, Liu X, Kim E, Strable M, Ntambi JM. (2010) Adipose-specific deletion of stearoyl-CoA desaturase 1 up-regulates the glucose transporter GLUT1 in adipose tissue. Biochem Biophys Res Commun. Sep 3;399(4):480-486. PMID: 20655875 [PubMed]

139. James M. Ntambi (2010) Role of Stearoyl-CoA desaturase in Regulating Obesity. ASBMB today May 2010 32.

138. Dobrzyn, P., Dobrzyn, A., Miyazaki, M., Ntambi, J.M. (2010) Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin deficient mice. J Lipid Res. Aug;51(8):2202-10. PMID: 20363835 [PubMed]

137. Strable, M.S., Ntambi, J.M. (2010) Genetic control of de novo lipogenesis: role in diet-induced obesity. Crit Rev Biochem Mol Biol. Jun;45(3):199-214. PMID: 20218765 [PubMed]

136. Liu, X., Miyazak,i M., Flowers, M.T., Sampath, H., Zhao, M., Chu, K., Paton, C.M., Joo, D.S., Ntambi, J.M. (2010)
Loss of Stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate. Arterioscler Thromb Vasc Biol. 30(1):31-8. PMID: 19910642 [PubMed]

135. Liu, X. and Ntambi, J.M. (2009) Atherosclerosis: keep your macrophages in shape. Nat Med.15(12):1357-8.
[PubMed]

134. Sampath, H., Flowers, M.T., Liu, X., Paton, C.M., Sullivan, R., Chu, K., Zhao, M., Ntambi, J.M. (2009)
Skin-specific deletion of stearoyl-CoA desaturase-1 alters skin lipid composition and protects mice from high fat diet-induced obesity. JBC 284(30):19961-73. [PubMed]

133. Florence Isabirye Muranga, Miriam Kanyago, Fabian Nabugoomu and James M. Ntambi (2009) Investigation of the potential of fortified instant Matooke flour (ITF) in rehabilitation of malnourished children (Part 2): Testing potential of ITF as a vehicle food for malnutrition intervention African Journal of Food Science Vol. 3(10). pp. 279-287. [JournalLink]

132. Florence Isabirye Muranga, Miriam Kanyago, Fabian Nabugoomu and James M. Ntambi (2009) Investigation of the potential of fortified instant Matooke flour (ITF) in rehabilitation of malnourished children (Part 1): Optimal level of fortification of instant Matooke flour porridge and its nutritional quality attributes. African Journal of Food Science Vol. 3(10) pp. 273-278. [JournalLink]

131. Miyazaki, M., Sampath, H., Liu, X., Flowers, M.T., Chu, K., Dobrzyn, A., Ntambi, J.M. (2009) Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice. Biochem Biophys Res Commun. 380(4):818-22. [PubMed]

130.  Flowers, M.T. and Ntambi, J.M. (2009) Stearoyl-CoA Desaturase and its Relation to High-Carbohydrate Diets and Obesity. Biochim Biophys Acta 1791 (2):85-91. [PubMed]

129. Paton, C.M., Ntambi, J.M. (2009) Biochemical and Physiological Function of Stearoyl-CoA Desaturase. Am J Physiol Endocrinol Metab. 297:28-37. [PubMed]

128. Flowers, M.T. and Ntambi, J.M. Gene Inactivation and Tissue-specific Metabolism. In: Encyclopedia of life sciences. John Wiley & Sons,Ltd: Chichester. http://www.els.net/

127. Miyazaki, M.,and Ntambi, J.M. (2008) Fatty acid desaturation and elongation in mammals. In: Biochemistry of Lipids, Lipoproteins and Membranes, 5th edition. Chapter 7. D.E. Vance and J.E. Vance ed. 191-211. [Science Direct]

126. Zarnowski, R., Dobrzyn, A., Ntambi, J.M., and Woods, J.P. (2008) Ferrous, but not Ferric, Iron Maintains Homeostasis in Histoplasma capsulatum triacylglycerides. Curr Microbiol. 57(2):153-7. [PubMed]

125. Zarnowski, R., Dobrzyn, A., Ntambi, J.M., and Woods, J.P. (2008) Neutral Storage Lipids of Histoplasma capsulatum : Effect of Culture Age. Curr Microbiol. Feb;56(2):110-4. [PubMed]

124. Dobrzyn, P., Sampath, H., Dobrzyn, A., Miyazaki, M., Ntambi, J.M. (2008) Loss of stearoyl-CoA desaturase 1 inhibits fatty acid oxidation and increases glucose utilization in the heart. Am J Physiol Endocrinol Metab. 294(2):E357-64.[PubMed]

123. MacDonald, M.J., Dobrzyn, A., Ntambi, J.M., Stoker, S.W. (2008) The role of rapid lipogenesis in insulin secretion: Insulin secretagogues acutely alter lipid composition of INS-1 832/13 cells. Archives of Biochemistry and Biophysics, Volume 470, Issue 2, 153-162. [ScienceDirect]

122. Flowers, M.T., Keller, M.P., Choi, Y., Lan, H., Kendziorski, C., Ntambi, J.M., Attie, A.D. (2008) Liver gene expression analysis reveals endoplasmic reticulum stress and metabolic dysfunction in SCD1-deficient mice fed a very low-fat diet. Physiol Genomics. 33:361-372 [PubMed]

121. Mar-Heyming, R., Miyazaki, M., Weissglas-Volkov, D., Kolaitis, N.A., Sadaat, N., Plaisier, C., Pajukanta, P., Cantor, R.M., de Bruin, T.W., Ntambi, J.M., Lusis, A.J. (2008) Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 28:1193-1199 [PubMed]

120. Flowers, M.T., and Ntambi, J.M. (2008) Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism. Curr Opin Lipidol. 19:248-256. Review [PubMed]

119. Sampath, H., and Ntambi, J.M. (2008) Role of stearoyl-CoA desaturase in human metabolic disease. Future Lipidology, Vol. 3, No. 2, 163-173. [JournalLink]

118. Dobrzyn, P., Ntambi, J.M., Dobrzyn, A. (2008) Stearoyl-CoA desaturase: A novel control point of lipid metabolism and insulin sensitivity. Eur. J. Lipid Sci. Technol, 110, 93-100. [WileyOnline]

117. Chen, C., Shah, Y.M., Morimura, K., Krausz, K.W., Miyazaki, M., Richardson, T.A., Morgan, E.T., Ntambi, J.M., Idle, J.R., Gonzalez, F.J. (2008) Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis. Cell Metab. 7:135-47 [PubMed]

116. Miyazaki, M., Flowers, M.T., Sampath, H., Chu, K., Otzelberger, C., Liu, X., Ntambi, J.M. (2007) Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. Cell Metab. 6:484-96 [PubMed]

115. McGinnis, J.M., Birt, D.F., Brannon, P.M., Carroll, R.J., Gibbons, R.D., Hazzard, W.R., Kamerow, D.B., Levin, B., Ntambi, J.M., Paneth, N., Rogers, D., Saftlas, A.F., Vaughan, W. (2007) Letters to the Editor: Reply to BN Ames et al. Am. J. Clinical Nutrition, 86:522-524. [JournalLink]

114. Mulanga, F.I., Sampath, H., Marlett, J.A., Ntambi, J.M. (2007) Impact of processing technique on apparent bioavaibility of cooking  banana (matooke) starch. African Journal of Biochemistry Research. 1(5), 72-77. [JournalLink]

113. Zarnowski, R., Miyazaki, M., Dobrzyn, A., Ntambi, J.M., Woods, J.P. (2007) Typing of Histoplasma capsulatum strains by fatty acid profile analysis. J Med Microbiol. 56:788-97. [PubMed]

112. Attie, A.D., Flowers, M.T., Flowers, J.B., Groen, A.K., Kuipers, F., Ntambi, J.M. (2007) Stearoyl-CoA desaturase deficiency, hypercholesterolemia, cholestasis, and diabetes. Nutr Rev. 65:S35-8. Review. [PubMed]

111. Flowers, J.B., Rabaglia, M.E., Schueler, K.L., Flowers, M.T., Lan, H., Keller, M.P., Ntambi J.M., Attie, A.D. (2007) Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice. Diabetes. 56(5):1228-39. [PubMed]

110. Thomson, B., Ahrens, J.M., Ntambi, J.M., DeLuca, H.F., Clagett-Dame, M. (2007) 2-Methylene-19-nor-1alpha-hydroxyvitamin D3 analogs inhibit adipocyte differentiation and PPARgamma2 gene transcription.
Arch Biochem Biophys. 460(2):192-201. [PubMed]

109. Sampath, H. and Ntambi, J. M. (2007) Polyunsaturated fatty acids and regulation of gene expression. In: Fatty Acids in Foods and Their Health Implications, Third Edition C. K. Chow, ed., CRC Press. 727-739

108. Sampath, H., Miyazaki, M., Dobrzyn, A., Ntambi, J.M. (2007) Stearoyl CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat. J Biol Chem. 282: 2483-93. [PubMed]

107. Marwah, A., Gomez, F. E., Marwah, P, Ntambi, J. M., Fox, B. G. and Lardy, H. (2007) Redox reactions of dehydroepiandrosterone and its metabolites in differentiating 3T3-L1 adipocytes. A liquid chromatographic-mass spectrometric study. Arch. Biochem. Biophys 456, 1-7. [PubMed]

106. Flowers, M. T., Groen, A. K., Oler, A., Keller, M. P., Choi, Y., Schueler, K. L., Richards, O. C., Lan, H., Miyazaki, M., Kuipers, F., Kendziorski, C., Ntambi, J. M. and Attie, A. D. (2006) Cholesterol and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet. J Lipid Res. Dec;47(12):2668-80. [PubMed]

105. Chu, K., Miyazaki, M., Man, W. C. and Ntambi, J. M. (2006) Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation. Mol. Cell. Biol. 26, 6786-6798. [PubMed]

104. McGinnis, J. M., Birt, D. F., Brannon, P. M., Carroll, R. J., Gibbons, R. D., Hazzard, W. R., Kamerow, D. B., Levin, B., Ntambi, J. M., Paneth, N., Rogers, D., Saftlas, A. F. and Vaughan, W. (2006) National Institutes of Health State-of-the-Science Conference Statement: Multivitamin/Mineral Supplements and Chronic Disease Prevention. Annals of Internal Medicine, Vol. 145, Issue No. 5, pp. 364-371.

103. Man, W. C., Miyazaki, M., Chu, K. and Ntambi, J. M. (2006) Co-localization of SCD1 and DGAT2: implying preference for endogenous monounsaturated fatty acids in triglyceride synthesis. J. Lipid Res. 47, 1928-1939. [JournalLink]

102. Sampath, H. and Ntambi, J. M. (2006) Regulation of gene expression by polyunsaturated fatty acids. Heart and Metabolism, 32:32-35. [Journal pdf]

101. Biddinger, S. B., Miyazaki, M., Boucher, J., Ntambi, J. M. and Kahn, C. R. (2006) Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c. Diabetes 55, 2032-2041. [PubMed]

100. Flowers, M. T., Miyazaki, M., Liu, X. and Ntambi, J. M. (2006) Probing the role of stearoyl-CoA desaturase-1 in hepatic insulin resistance. J. Clin. Invest. 116, 1478-1481. [PubMed]

99. Ntambi, J. M. (2006) Lipids, genes, and health.Book review. Science 312, 698. [ScienceLink]

98. Miyazaki, M., Bruggink, S. M. and Ntambi, J. M. (2006) Identification of mouse palmitoyl-coenzyme A Delta9-desaturase. J. Lipid Res. 47, 700-704. [PubMed]

97. Sampath, H. and Ntambi, J. M. (2006) Stearoyl-coenzyme A desaturase 1, sterol regulatory element binding protein-1c and peroxisome proliferators-activated receptor-alpha: Independent and interactive roles in the regulation of lipid metabolism. Curr. Opin. Clin. Nutr. Metab. Care 9, 84-88. [PubMed]

96. Weng Chi Man, Makoto Miyazaki, Kiki Chu and James M. Ntambi (2006) Membrane topology of mouse stearoyl-CoA desaturase 1. J. Biol. Chem. Jan 13; 281(2): 1251-1260. [PubMed]

95. Sampath H, Ntambi JM. (2005)The fate and intermediary metabolism of stearic acid. Lipids. Dec;40(12):1187-91. Review. [PubMed]

94. Ntambi JM, Sampth H. (2005) Dietary Regulation of Stearoyl-CoA Desaturase-1 expression. Proceedings of the 18th International Congress of Nutrition 19-23 September, 2005 Durban South Africa.

93. Matthew Hulver, Jason R. Berggren, Michael J. Carper, Makoto Miyazaki, James M. Ntambi, Eric P. Hoffman, G. Lynis Dohm, Joseph A. Houmard and Deborah M. Muoio (2005) Elevated Stearoyl-CoA Desaturase-1 Expression in Skeletal Muscle Contributes to Abnormal Fatty Acid Partitioning in Obese Humans. Cell Metab. Oct; 2(4): 251-261. [PubMed]

92. Makoto Miyazaki, Agnieszka Dobrzyn, Peter M. Elias and James M. Ntambi (2005) Stearoyl-CoA desaturse-2 gene expression is required for lipid synthesis during early skin and liver development. Proc. Natl. Acad. Sci. USA. Aug 30; 102(35): 12501-12506. [PubMed]

91. Agnieszka Dobrzyn, Pawel Dobrzyn, Makoto Miyazaki, James M. Ntambi (2005) Polyunsaturated fatty acids do not activate AMP-activated protein kinase in mouse tissues. Biochem. Biophys. Res. Commun. Jul 8; 332(3): 892-6. [PubMed]

90. Agnieszka Dobrzyn and James M. Ntambi (2005) Stearoyl-CoA desaturase as a new drug target for obesity. Obesity Reviews. May;6(2):169-74. [PubMed]

89. Dobrzyn, A. and Ntambi, J. M. (2005) The role of stearoyl-CoA desaturase in the control of metabolism. Prostaglandins, Leukot. Essent. Fatty Acids 73, 35-41. [PubMed]

88. Agnieszka Dobrzyn, Pawel Dobrzyn, Makoto Miyazaki, Harini Sampath, Kiki Chu, and James M. Ntambi (2005) Stearoyl-CoA desaturase 1 deficiency increases CTP: choline cytidylyltransferase translocation into the membrane and enhances phosphatidylcholine synthesis in liver. J. Biol. Chem. Jun 17; 280(24): 23356-23362. [PubMed]

87. Agnieszka Dobrzyn and James Ntambi (2005) Stearoyl-CoA desaturase: a therapeutic target of insulin resistance and diabetes. Drug Discovery Today: Therapeutic Strategies. 2(2): 125-128. [ScienceDirect]

86. Sudha B. Biddinger, Katrine Almind, Makoto Miyazaki, Efi Kokkotou, James M. Ntambi, and C. Ronald Kahn (2005) Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome.Diabetes May; 54(5): 1314-1323. [PubMed]

85. Harini Sampath and James M. Ntambi (2005) Polyunsaturated fatty acid regulation of genes of lipid metabolism. Annu Rev Nutr. 25: 317-340. [PubMed]

84. Dobrzyn, A. and Ntambi, J. M.  (2005) Stearoyl-CoA desaturase as a new drug target for obesity treatment. Obesity Reviews. May; 6(2): 169-174. [PubMed]

83. Dobrzyn, A., Dobrzyn, P., Lee, S. H., Miyazaki, M., Cohen, P., Asilmaz, E., Hardie, D. G., Friedman, J. M. and Ntambi, J. M.  (2005) Stearoyl-CoA desaturase 1 deficiency reduces ceramide synthesis by down-regulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle. Am J. Physiol. Endocrinol. Metab. Mar; 288(3): 599-607. [PubMed]

82. Rahman, S. M., Dobrzyn, A., Lee, S. H., Dobrzyn, P., Miyazaki, M. and Ntambi, J. M. (2005) Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue. Am J. Physiol. Endocrinol. Metab. Feb; 288(2): 381-387. [PubMed]

81. Ntambi, J. M., Miyazaki, M. and Dobrzyn, A.  (2004) Regulation of Stearoyl-CoA Desaturase Expression. Lipids. Nov; 39(11): 1061-1065. [SpringerLink]

80. Sampath, H. and Ntambi, J. M.  (2004) Polyunsaturated Fatty Acid Regulation of Gene expression (2004) Nutrition Reviews. Sep; 62(9): 333-339. [WileyOnline]

79. SLee, S. H., Dobrzyn, A., Dobrzyn, P., Rahman, S. M., Miyazaki, M. and Ntambi, J. M. (2004) Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis, but causes hypothermia in cold environment J. Lipid. Res. Sep 45(9): 1674-1682. [PubMed]

78. Miyazaki, M., Dobrzyn, A., Sampath, H., Lee, S. H., Man, W. C., Chu, K., Peters, J. M., Gonzalez, F. J. and Ntambi, J. M.  (2004) Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha. J. Biol. Chem. Aug 13; 279(33): 35017-35024. [PubMed]

77. Miyazaki, M., Dobrzyn, A., Man, W. C., Chu, K., Sampath, H., Kim, H. J. and Ntambi, J. M. (2004) Stearoyl-CoA desaturase gene 1 expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element binding protein-1c-dependent and independent mechanisms J. Biol. Chem. June 11; 279(24): 25164-25171. [ PubMed]

76. Dobrzyn, P., Dobrzyn, A., Miyazaki, M., Cohen, P., Asilmaz, E., Hardie, G. D., Friedman, J. M. and Ntambi, J. M.  (2004)  Stearoyl-CoA desaturase-1 (SCD1) deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver.  Proc. Natl. Acad. Sci. USA. April; 101(17): 6409-6414. [PubMed]

75. Wilson, R. A., Chang, P.-K., Dobrzyn, A, Ntambi, J. M. and Keller, N. O. (2004). Two Delta9-stearic acid desaturases are required for Aspergillus nidulans growth and development. Fungal Genetics and Biology May; 41(5): 501-50. [PubMed]

74. Ntambi, J. M. and Georgieff, M. (2004) Testing Ingredients with Preclinical Studies Infant formula: Evaluating the Safety of New Ingredients, Institute of Medicine, National Research Council of the National Academies.

73. Dobrzyn, A. and Ntambi, J. M. (2004) The role of stearoyl-CoA desaturase in body weight regulation. Trends in Cardiovascular Medicine, 14, 77-81. [PubMed]

72. Asilmaz, E., Cohen, P., Miyazaki, M., Dobrzyn, P., Ueki, K., Fayzikhodjaeva, G., Soukas, A. A., Kahn, C. R., Ntambi, J. M., Socci, N. D. and Friedman, J. M. (2004) Site and mechanism of leptin action in a rodent form of congenital lipodystrophy. Journal of CIinical Investigation. Feb; 113(3): 414-24. [PubMed]

71. Kang, K., Miyazaki, M., Ntambi, J. M. and Pariza, M. W. (2004) Evidence that the anti-obesity effect of conjugated linoleic acid is independent of effects on stearoyl-CoA desaturase 1 expression and enzyme activity. Biochem. Biophys. Res. Commun. 315, 532-537 (2004). [PubMed]

70. Ntambi, J. M. and Miyazaki, M.  (2004) Regulation of Stearoyl-CoA Desaturases and Role in Metabolism. Prog Lipid Res. 2004 Mar; 43(2): 91-104. [PubMed]

69. Cohen P., Ntambi J.M., and Friedman J.M. (2003) Stearoyl-CoA Desaturase-1 and the Metabolic Syndrome. Current Drug Targets - Immune, Endocrine & Metabolic Disorders, vol. 3, no. 4, pp. 271-280(10). [PubMed]

68. Rahman, S. M., Dobrzyn, A., Dobrzyn, P., Lee, S. H., Miyazaki, M. and Ntambi, J. M. (2003) Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle. Proc Natl Acad Sci U S A. Sep 16; 100(19): 11110-5. [PubMed]

67. Miyazaki, M., Jacobson, M. J., Man, W. C., Cohen, P., Asilmaz, E., Friedman, J. M. and Ntambi, J. M. (2003) Identification and characterization of murine SCD4: a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors. J Biol Chem. Sep 5; 278(36): 33904-11. [PubMed]

66. Ntambi, J. M. and Miyazaki, M.  (2003) Recent insights into Stearoyl-CoA Desaturase-1. Curr Opin. Lipidol 14, 255-261. [PubMed]

65. Miyazaki, M., Gomez, F. E. and Ntambi, J. M. (2003). Presence of a palmitoyl-CoA desaturase in the preputial gland of the mouse. Advance Research on Plant Lipids: Proceedings of the 15th International Symposium on Plant Lipids, Okazaki, Japan. 95-99.

64. Gomez, F. E., Bauman, D. E., Ntambi, J. M. and Fox, B. G.  (2003) Effects of Sterculic Acid on Stearoyl-CoA Desaturase (SCD) in Differentiating 3T3-L1 Adipocytes. BBRC 300, 316-326. [PubMed]

63. Pariza, M. W., Park, Y., Xu, X., Ntambi, J. and Kang, K. (2003) Speculation on the mechanisms of action of conjugated linoleic acid. In: Advances in Conjugated Linoleic Acid Research, Vol. 2, J. L. Sebedio, ed., AOCS Press, Champaign, IL.

62. Miyazaki, M and Ntambi, J. M. (2003) Role of stearoyl-coenzyme A desaturase in lipid metabolism. Prostaglandins Leukot. Essent. Fatty Acids 68, 113-121. [PubMed]

61. Laviano, A., Meguid, M. M., Rossi-Fanelli, F., Cohen, P., Miyazaki, M., Hudgins, L. C., Socci, N. D., Ntambi, J. M., Hagge-Greenberg, A., Liedtke, W., Soukas, A. A., Sharma, R. and Friedman, J. M. (2002) Energy expenditure and treating obesity. Science 298, 539-541. [ScienceLink]

60. Miyazaki, M., Gomez, F. E. and Ntambi, J. M. (2002) Lack of Stearoyl-CoA desaturase-1 function induces a palmitoyl-CoA Delta6 desaturase and represses the stearoyl-CoA desaturase-3 gene in the preputial gland of the mouse. J. Lipid Res. 43, 2146-2154. [PubMed]

59. Attie, A. D., Krauss, R. M., Gray-Keller, M. P., Brownlie, A., Miyazaki, M., Kastelein, J. J., Lusis, A. J., Stalenhoef, A. F. H., Stoehr, J. P., Hayden, M. R. and Ntambi, J. M. (2002) Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia.  J. Lipid Res 43, 1899-1907. [PubMed]

58. Kim, H.-J., Miyazaki, M. and Ntambi, J. M.  (2002) Dietary cholesterol opposes PUFA-mediated repression of the stearoyl-CoA desaturase 1 gene by Sterol Regulatory Element-binding Protein-1 independent mechanism J. Lipid Res. 43, 1750-1757. [PubMed]

57. Ntambi, J. M., Choi, Y., Park, Y., Peters, J. M. and Pariza, M. W. (2002). Effects of conjugated linoleic acid (CLA) on immune responses, body composition and stearoyl-CoA desaturase. CJAP, 27, 617-627. [PubMed]

56. Cohen, P., Miyazaki, M., Hudgins, L. C., Socci, N D, Ntambi, J. M., Hagge-Greenberg, A., Liedtke, W., Soukas, A. A., Sharma, R. and Friedman, J. M. (2002). Energy expenditure and treating obesity. Science 298, 539-541. [ScienceLink]

55. Ntambi, J. M., Miyazaki, M., Stoehr, J. P., Lan, H., Kendziorski, C. M., Yandell, B. S., Cohen, P, Friedman, J. and Attie, A. D.  (2002) Loss of Stearoyl CoA Desaturase-1 Function Protects Mice Against Adiposity. Pro. Nat. Acad. Sci 99, 11482-11486. [PubMed]

54. Cohen, P., Miyazaki, M., Socci, N D, Hagge-Greenberg, A., Liedtke, W., Soukas, A. A., Sharma, R., Hudgins, L. C., Ntambi, J. M. and Friedman, J. M.  (2002) Role for stearoyl-CoA desaturase-1 in leptin mediated weight loss. Science 297, 240-243. [PubMed]

53. Choi, Y., Parka, Y., Storkson, J. M., Pariza, M. and Ntambi, J. M.  (2002) Inhibition of stearoyl-CoA Desaturase activity by the cis-9, trans-11 isomer and the trans-10, cis-12 isomer of conjugated linoleic acid in MDA-MB-231 and MCF-7 human breast cancer cells. BBRC 294, 785-790. [PubMed]

52. Kim, H.-J., Miyazaki, M., Man, W. C. and Ntambi, J. M. (2002). Sterol Regulatory Element Binding proteins (SREBPs) as Regulators of Lipid Metabolism: Polyunsaturate Fatty Acids Oppose Cholesterol-Mediated Induction of SREBP-1c Maturation. Annals of the New York Academy of Sciences 967, 34-42. [PubMed]

51. Gomez, E.F., Miyazaki, M., Marwah, P., Lardy, H.A., Ntambi, J.M. and Fox, B.G. (2002). Molecular Differences Caused by Differentiation of 3T3-L1 Preadipocytes in the Presence of either Dehydroepiandosterone (DHEA) or 7-Oxo-DHEA. Biochemistry, 41, 5473-5482. [PubMed]

50. Lasky, D., Becerra, E., Boto, W., Otim, M.,and Ntambi, J. M. (2002). Obesity and gender differences in the risk of type 2 diabetes mellitus in Uganda. Nutrition 18 (5) 417-421. [PubMed]

49. Miyazaki, M., Kim, H.-J., Man, W.C. and Ntambi, J. M (2001) Oleoyl-CoA is the Major De novo Product of Stearoyl-CoA Desaturase 1 Gene Isoform and Substrate for the Biosynthesis of the Harderian Gland 1-Alkyl-2,3-Diacylglycerol. J. Biol. Chem. 276, 39455-39461. [PubMed]

48. Miyazaki, M., Man, W.C. and Ntambi, J. M. (2001) Targeted Disruption of Stearoyl-CoA Desaturase1 Gene in Mice Causes Atrophy of Sebaceous and Meibomian Glands and Depletion of Wax Esters in the Eyelid. J. Nutr. 131, 2260-2268. [PubMed]

47. Bene, H., Lasky, D. and Ntambi, J. M. (2001). The cloning and characterization of the human stearoyl-CoA desaturase gene promoter: Transcriptional activation by sterol regulatory element binding protein and repression by polyunsaturated fatty acids and cholesterol. Biochem. Biophys. Res. Commun. 284, 1194-1198. [PubMed]

46. Choi, Y., Park, Y., Pariza, M. W. and Ntambi, J. M. (2001). Regulation of stearoyl-CoA desaturase activity by the trans-10, cis-12 isomer of conjugated linoleic acid in HepG2 cells. Biochem. Biophys. Res. Commun. 284, 689-693. [PubMed]

45. Ntambi, J. M. and Kim, Y.-C. (2001). Regulation of stearoyl-CoA desaturase gene expression: Role of polyunsaturated fatty acids. In: Nutrition and Gene Expression, CRS Press, pp. 49-61. 

44. Miyazaki, M., Kim, Y.-C. and Ntambi, J. M. (2001). A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis. J. Lipid Res. 42, 1018-1024. [JournalLink

43. Ntambi, J. M. and Bene, H. (2001). Polyunsaturated fatty acid regulation of gene expression. J. Mol. Neurosci. 16, 273-278. [SpringerLink]

42. Ntambi, J. M. and Kim, Y.-C. (2000). Adipocyte differentiation and gene expression. J. Nutr. 130, 3122S-3126S. [PubMed]

41. Miyazaki, M., Kim, Y.-C., Gray-Keller, M. P., Attie, A. D. and Ntambi, J. M. (2000). The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption in the gene for stearoyl-CoA desaturase 1. J. Biol. Chem. 275, 30132-30138. [PubMed]

40. Park, Y., Storkson, J. M., Ntambi, J. M., Cook, M. E., Sih, C. J. and Pariza, M. (2000). Inhibition of hepatic stearoyl-CoA desaturase activity by trans-10, cis-12 conjugated linoleic acid and its derivatives. Biochim. Biophys. Acta 1486, 285-292. [PubMed]

39. Kim, Y.-C., Gomez, E., Fox, B. G. and Ntambi, J. M. (2000). Differential regulation of the stearoyl-CoA desaturase genes by thiazolidinediones in 3T3-L1 adipocytes. J. Lipid Res. 41, 1310-1316. [PubMed]

38. Choi, Y., Kim, Y.-C., Han, Y.-B., Park, Y., Pariza, M. W. and Ntambi, J. M. (2000). The trans-10, cis-12 isomer of conjugated linoleic acid downregulates stearoyl-CoA desaturase gene expression in 3T3-L1 adipocytes. J. Nutr. 130, 1920-1924. [PubMed]

37. Kim, Y.-C., Gomez, E., Fox, B. G. and Ntambi, J. M. (2000). Regulation of stearoyl-CoA desaturase 1 gene expression in preadipocyte differentiation, diabetes and obesity. In: Adipocyte Biology and Hormone Signaling, 27th Steenbock Symposium, Madison, WI, June, 1999 (J. M. Ntambi, ed.), IOS Press, The Netherlands, pp. 69-78.

36. Ntambi, J. M. and Sessler, A. M. (1999). Fatty acid regulation of gene expressions and fat cell differentiation. In: Fatty Acids in Foods and Their Health Implications, Chapter 28 (C. K. Chow, ed.), Marcel Dekker Inc., New York, pp. 597-606.

35. Kim, Y.-C. and Ntambi, J. M. (1999). Regulation of stearoyl-CoA desaturase genes: Role in cellular metabolism and preadipocyte differentiation. Biochem. Biophys. Res. Commun. 266, 1-4. [PubMed]

34. Ntambi, J. M. (1999). Regulation of stearoyl-CoA desaturase in preadipocyte differentiation and metabolism. Chem. Phys. Lipids 101, 142.

33. Ntambi, J. M. (1999). Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol. J. Lipid Res. 40, 1549-1558. [PubMed]

32. Ntambi, J. M., Choi, Y. and Kim, Y.-C. (1999). Regulation of stearoyl-CoA desaturase by conjugated linoleic acid AOCS. In: Conjugated Linoleic Acid: Biochemical, Nutritional, Clinical, Cancer and Methodological Aspects, Vol. 26, pp. 340-347.

31. Miller, C. C. and Ntambi, J. M. (1998). The role of prostaglandin F2a in the inhibition of fat cell differentiation. Recent Res. Develop. in Lipids Res. 2, 11-19.

30. Lee, K. N., Pariza M. W. and Ntambi, J. M. (1998). Conjugated linoleic acid decreases hepatic stearoyl-CoA desaturase mRNA expression. Biochem. Biophys. Res. Commun. 248, 817-821 [PubMed]

29. Singh, M. and Ntambi, J. M. (1998). Nuclear Factor 1 is essential for expression of stearoyl-CoA desaturase 1 gene during preadipocyte differentiation. Biochim. Biophys. Acta 1398, 148-156. [PubMed]

28. Sessler, N. and Ntambi, J. M. (1998). Polyunsaturated fatty acid regulation of gene expression. J. Nutr. 128, 923-926. [PubMed]

27. Waters, K. M., Miller, C. W. and Ntambi, J. M. (1997). Localization of a polyunsaturated fatty acid response region in stearoyl-CoA desaturase gene 1. Biochim. Biophys. Acta 1349, 33-42. [PubMed]

26. Ntambi, J. M. (1997). Fat cell differentiation blocked by prostaglandin F2a stimulation of the prostanoid FP2 receptor. Emerging Therapeutic Targets 1, 237-240.

25. Waters, K. M., Miller, C.W. and Ntambi, J. M. (1997). Localization of a negative thyroid hormone-response element in hepatic stearoyl-CoA desaturase gene 1. Biochem. Biophys. Res. Commun. 233, 838-843. [PubMed]

24. Miller, C. W., Waters, K. M. and Ntambi, J. M. (1997). Regulation of hepatic stearoyl-CoA desaturase gene 1 by vitamin A. Biochem. Biophys. Res. Comm. 231, 206-210. [PubMed]

23. Lee, K. N., Pariza, M. and Ntambi, J. M. (1996). Differential expression of hepatic stearoyl-CoA desaturase gene 1 in male and female mice. Biochim. Biophys. Acta 1304, 85-88. [PubMed]

22. Miller, C. W., Casimir, D. A. and Ntambi, J. M. (1996). The mechanism of inhibition of 3T3-L1 preadipocyte differentiation by prostaglindin F2alpha. Endocrinology 137, 5641-5650. [PubMed]

21. Sessler, A., Kaur, N., Palta, J.P. and Ntambi, J. M. (1996). Regulation of stearoyl-CoA desaturase1 mRNA stability by polyunsaturated fatty acids in 3T3-L1 adipocyes. J. Biol. Chem. 271, 29854-29858. [PubMed]

20. Casimir, D. A. and Ntambi, J. M. (1996). cAMP activates the expression of stearoyl-CoA desaturase gene 1 during early preadipocyte differentiation. J. Biol. Chem. 271, 29847-29853. [PubMed]

19. Casimir, D. A., Miller, C. W. and Ntambi, J. M. (1996). Preadipocyte differentiation blocked by prostaglandin stimulation of FP receptor. South African J. Sci. 92, Abs., p. 563.

18. Miller, C. W. and Ntambi, J. M. (1996). Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression. Proc. Natl. Acad. Sci. USA 93, 9443-9448. [PubMed]

17. Casimir, D. A., Miller, C. W. and Ntambi, J. M (1996). Preadipocyte differentiation blocked by prostaglandin stimulation of prostanoid FP2 receptor in murine 3T3-L1 cells. Differentiation 60, 203-210. [PubMed]

16. Ntambi, J. M. and Takova, T. (1996). Role of Ca2+ in the early stages of murine adipocyte differentiation as evidenced by calcium mobilizing agents. Differentiation 60, 151-158. [PubMed]

15. Waters, K. and Ntambi, J. M. (1996). Polyunsaturated fatty acids inhibit hepatic stearoyl-CoA desaturase 1 gene in diabetic mice. Lipids 31, S-33-S-36. [PubMed]

14. Ntambi, J. M., Sessler, A. M. and Takova, T. (1996). A model cell line to study regulation of stearoyl-CoA desaturase gene 1 expression by insulin and polyunsaturated fatty acids. Biochem. Biophys. Res. Commun. 220, 990-995. [PubMed]

13. Smulson, M. E., Kang, V. H., Ntambi, J. M., Rosenthal, D. S., Ding, R. and Simbulan, C. M. (1995). Requirement for the expression of poly (ADP-ribose) polymerase during the early stages of differentiation of 3T3-L1 preadiopcytes as studied by antisense RNA induction. J. Biol. Chem. 270, 119-127. [PubMed]

12. Ntambi, J. M. (1995) The regulation of stearoyl-CoA desaturase (SCD). Prog. Lipid Res. 34, 139-150. [PubMed]

11. Ntambi, J. M. (1995) Cellular differentiation and dietary regulation of gene expression. Prostaglandins Leukotrienes and Essential Fatty Acids 52, 117-120. [ScienceDirect]

10. Waters, K. and Ntambi, J. M. (1994) Insulin and dietary fructose induce stearoyl-CoA desaturase 1 gene expression in liver of diabetic mice. J. Biol. Chem. 269, 27773-27777. [PubMed]

9. Pastano, G., Prince, A., Guyden, J., Ntambi, J. M., Atkin, A. and Boto, W. O. (1993) Independent divergence in the CD4 binding site and V3 loop encoded in two seroprevalent Ugandan HIV-1 clinical isolates. J. Acq. Immune Def. Syndromes 6, 872-80. [PubMed]

8. Ntambi, J. M. (1992) Dietary regulation of stearoyl-CoA desaturase 1 gene expression in mouse liver. J. Biol. Chem. 267, 10925-10930. [PubMed]

7. Christy, R. J., Young, V. W., Ntambi, J. M., Geiman, D. E., Landschulz, W. H., Friedman, A. D., Nakabeppu, Y., Kelly, T. J. and Lane, M. D. (1989) Differentiation-induced gene expression in 3T3-L1 preadipocytes: C/EBP interacts with and activates the promoters of two adipocyte-specific genes. Genes and Development 9, 1323-1335. [PubMed]

6. Kaestner, K. H., Ntambi, J. M., Kelly, T. J. and Lane, M. D. (1989) Differentiation-induced gene expression in 3T3-L1 preadipocytes: A second differentially expressed gene encoding stearoyl-CoA desaturase. J. Biol. Chem. 264, 14755-14761. [PubMed]

5. Ntambi, J. M., Buhrow, S. A., Kaestner, K. H., Sibley, E., Christy, R. J., Kelly, T. J. and Lane, M. D. (1988) Differentiation-induced gene expression in 3T3-L1 preadipocytes: Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase. J. Biol. Chem. 263, 17291-17300. [PubMed]

4. Ntambi, J. M., Ryan, K. A. and Englund, P. T. (1987) The replication origin in kinetoplast DNA minicircles from Trypanosoma equiperdum. In: Molecular Biology of Parasitic Invasion, Alan R. Liss, Inc., pp. 113-120.

3. Ntambi, J. M., Shapiro, T., Ryan, K. A. and Englund, P. T. (1986) Ribonucleotides associated with a gap in newly replicated kinetoplast DNA minicircles from Trypanosoma equiperdum. J. Biol. Chem. 261, 11890-11895. [PubMed]

2. Ntambi, J. M. and Englund, P. T. (1985) A gap at a unique location in newly replicated kinetoplast DNA minicircles from Trypanosoma equiperdum. J. Biol. Chem. 260, 5574-5579. [PubMed]

1. Ntambi, J. M., Marini, J. C., Bangs, J. D., Hajduk, S. L., Jiminez, H. E., Kitchin, P. A., Klein, V. A., Ryan, K. A. and Englund, P. T. (1984) The presence of bent helix in the fragments of kinetoplast DNA minicircles from several trypanosomatid species. Mol. Biochem. Parasitol. 12, 273-286. [PubMed]