Protein- and lipid-binding features of COQ9 and its role in coenzyme Q biosynthesis
All students who take introductory science learn about how mitochondria supply the cell with energy. What may surprise you is how little we actually know about the organelle and its many proteins. The Pagliarini Lab works to identify the function of these proteins. Danielle Lohman is finishing up her work on a protein implicated in a disease called coenzyme Q deficiency. Her investigation into this protein helped her stumble onto a basic biology problem as well. She thinks that the protein is involved in getting hydrophobic lipids — water-repelling molecules — out of the mitochondrial membrane where they would normally be embedded.
Learn more about her research at her Thesis Review at 11 a.m. on Monday, Oct. 9 in the Hector F. DeLuca Biochemical Sciences Building.