Role of UCP1 in monounsaturated fatty acid homeostasis and adipose tissue inflammation
How do different environmental and genetic factors affect how we metabolize fats? Laura Bond, a graduate student in the lab of Professor James Ntambi, has been trying to find out in her Ph.D. research. Looking at mice, she found a mutation in UCP1, a protein that is essential for generating body heat in brown fat cells. The loss of UCP1 increased synthesis of monounsaturated fatty acids in white fat cells, which has important implications in metabolic health. Her work improves our understanding of lipid metabolism and obesity.
Learn more about her results at her Thesis Review at 1 p.m. on July 19 in the Khorana Auditorium of the Hector F. DeLuca Biochemistry Laboratories.