Of mice, microbiota, and squirrels: Interactions between metabolism, the gut microbiota, and the host epigenome
In recent years, more and more scientists have started to investigate the gut microbiome, which is the collection of all the microbes in the gut. By studying mice with controlled gut microbiomes in collaboration with the Federico Rey Lab in Bacteriology, Kimberly Krautkramer of the Denu Lab has linked diet-dependent changes in microbial community composition and metabolite production to alterations in epigenetic programming throughout the body — ultimately affecting gene expression.
“It’s very satisfying to provide molecular evidence for one of many reasons why the food we eat really matters,” she says. Learn more about her work on Tuesday, March 14 at 1 p.m. in Room 3280 WID (Orchard View Room).