BIOCHEMISTRY

Sponsored Presentation and Instrument Demonstrations

Studies Of Molecular Interaction Using MicroScale Thermophoresisand Stability Characterization Using nanoDSF
 

Talk by
Wyatt Strutz, Senior Applications Specialist
NanoTemper Technologies Inc, San Francisco CA
Tuesday March 7 at 10:00 am
Khorana Auditorium, Rm 175 Biochemistry Laboratories

Demonstrations will be held in
4420 Hector F Deluca Biochemical Sciences Bldg
on March 7 & 8

For those interested in running sample during the demonstrations (either the thermophoresis instruments or the
nanoDSC), registration forms are available from bifmaster@biochem.wisc.edu

MicroScale Thermophoresis is a versatile technique for quantitative molecular interaction characterization that does not require immobilization. Its applications range from small molecule screening to macromolecular complex assemblies.

nanoDSF is a powerful method to assess conformational and colloidal stability. It is a label free technology thatuses NanoTemper’s patented capillary technology to harness intrinsic protein fluorescence for unparalleled mapping of protein unfolding and aggregation. Applications include membrane protein detergent screening, cryo-EM sample optimization and formulation stability characterization

For those interested in participating in the demonstrations, there are a limited number of spots available on both Thermophoresis instruments (one uses intrinsic protein fluorescence, the other a dye) and the nanoDSC. Registration forms with more details and to be completed by the user are available from bifmaster@biochem.wisc.edu to be returned to wyatt.strutz@nanotemper-technologies.com. Technical inquiries should also be directed to Wyatt.