BIOCHEMISTRY

Research Area: Molecular mechanism of action of the vitamin A metabolite, all-trans retinoic acid, in nervous system development; the therapeutic use of vitamin A and D analogs

Research Area: Mechanisms of enzyme and coenzyme action; stereochemistry and mechanisms of phospho- and nucleotidyl transferase action; structure and function of multienzyme complexes

Research Area: Biomolecular recognition processes; the chemistry and biology of protein-saccharide interactions

Research Area: NMR spectroscopy and its biological applications; structure function relationships in proteins; stable-isotope-assisted multinuclear magnetic resonance spectroscopy; processing and analysis of multi-dimensional NMR data; structural genomics; metabolomics

Research Area: Biochemistry of behavior in Paramecium: Role of Ca2+, cyclic nucleotides, and protein kinases

Research Area: Transcriptional mechanisms of steroid hormone action in the skeleton

Research Area: Activation of enzymic reactions by metal ions; biophysical applications of spectroscopy

Research Area: Structures and the infection cycles of viruses with small RNA genomes, including the common cold virus